AV Matveyenko, JD Veldhuis, PC Butler - Diabetes, 2006 - Am Diabetes Assoc Impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) often
coexist and as such represent a potent risk factor for subsequent development of
type 2 diabetes. β-Cell mass is ∼50% deficient in IFG and ∼65% ... Cited by 21 - Related articles - BL Direct - All 6 versions
JI Stagner, E Samols - Diabetes, 1991 - Am Diabetes Assoc The metabolic consequences of hemipancreatectomy in living pancreas donors were
tested in a dog model in which a 50% lobe-specific pancreatectomy was performed.
Removal of the dorsal lobe (analogous to a donor, n = 4) resulted in a ... Cited by 8 - Related articles - All 4 versions
JJ Meier, AE Butler, R Galasso, RA Rizza, PC … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Type 1 and type 2 diabetes are charac- terised by a
beta cell deficit. Islet hyperplasia has been described in patients with
Zollinger–Ellison syndrome secondary to gastrin-producing tumours ... Cited by 21 - Related articles - BL Direct - All 5 versions
RA Ritzel, AE Butler, RA Rizza, JD Veldhuis, … - Diabetes Care, 2006 - Am Diabetes Assoc In type 2 diabetes there is a progressive defect of insulin secretion that
precedes the development of hyperglycemia (1). This defect appears to be at
least in part due to a deficit in β-cell mass (2–4). Several therapeutic ... Cited by 41 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org LL Kjems, BM Kirby, EM Welsh, JD Veldhuis, M … - Diabetes, 2001 - Am Diabetes Assoc Most insulin is secreted in discrete pulses at an interval of ∼6 min.
Increased insulin secretion after meal ingestion is achieved through the
mechanism of amplification of the burst mass. Conversely, in type 2 ... Cited by 74 - Related articles - BL Direct - All 6 versions
RP Robertson, KJ Lanz, DE Sutherland, ER … - Transplantation, 2002 - ncbi.nlm.nih.gov BACKGROUND: Healthy human volunteers occasionally elect to undergo surgical
removal of the distal half of their pancreas for donation to a relative with
type 1 diabetes. This provides the unusual opportunity to study segments of ... Cited by 35 - Related articles - BL Direct - All 2 versions
AF Kumar, RWG Gruessner, ER Seaquist - Diabetes Care, 2008 - Am Diabetes Assoc OBJECTIVE—Hemipancreatectomy (HPx) for the purpose of organ donation has been
associated with a 25% risk of developing abnormal glucose tolerance or diabetes
in the year after surgery. Since 1997, the University of Minnesota has ... Cited by 10 - Related articles - All 5 versions
F Marincola, LF Cobb, A Horaguchi, M Maeda, … - American Journal of Physiology- Endocrinology And …, 1984 - Am Physiological Soc MARINCOLA, F., L. F, COBB, A. HORAGUCHI, M. MAEDA, AND R. MERRELL. Accommodation
to a reduced islet cell mass in dogs. Am. J. Physiol. 247 (Endocrinol. Metab.
10): E456- E46f, 1984.-The quantitative insulin response to glucose stim- ... Cited by 10 - Related articles - All 3 versions
CJ Goodner, DJ Koerker, DS Weigle, DK … - Diabetes, 1989 - Am Diabetes Assoc The effect of beta-cell deficiency on the spontaneous pulsatile secretory
pattern of the islets of Langerhans was studied in the baboon. Measures of
beta-cell function were correlated with the secretory pattern before and at ... Cited by 27 - Related articles - All 4 versions
