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CD40–CD40 ligand interaction activates proinflammatory pathways in pancreatic islets

- diabetesresearch.org [PDF] 
FM Barbé-Tuana, D Klein, H Ichii, DM Berman, … - Diabetes, 2006 - Am Diabetes Assoc
Pancreatic islet transplantation is becoming an alternative to insulin therapy
in patients suffering from brittle type 1 diabetes. A major obstacle to the
procedure is the early graft loss caused by nonspecific inflammation at the ...
Cited by 20 - Related articles - BL Direct - All 7 versions

您所在位置: 首页> 期刊> 过刊浏览> 内科学>《 糖尿病学杂志》> 2006 年 9 月 55 卷 9 期> 文章 …


FM Barbe-Tuana, D Klein, H Ichii, DM Berman, … - journal.shouxi.net
Pancreatic islet transplantation is becoming an alternative to insulin therapy
in patients suffering from brittle type 1 diabetes. A major obstacle to the
procedure is the early graft loss caused by nonspecific inflammation at the ...
Related articles - Cached

Identification of three novel peptides that inhibit CD40–CD154 interaction


M Kitagawa, D Goto, M Mamura, I Matsumoto, … - Modern Rheumatology, 2005 - Springer
Abstract The CD40–CD154 interaction is an attractive tar- get for therapeutic
intervention in various autoimmune disorders, including rheumatoid arthritis,
systemic lupus erythematosus (SLE), multiple sclerosis, and myasthenia ...
Cited by 8 - Related articles - BL Direct - All 3 versions

A functional CD40 receptor is expressed in pancreatic beta cells


D Klein, F Barbe-Tuana, A Pugliese, H Ichii, … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 268–276 DOI 10.1007/s00125-004-1645-7 ARTICLE D.
Klein . F. Barbé-Tuana . A. Pugliese . H. Ichii . D. Garza . M. Gonzalez . ...
Cited by 18 - Related articles - All 3 versions

Inhibition of CD40–CD154 costimulatory pathway by a cyclic peptide targeting CD154


I Deambrosis, S Lamorte, F Giaretta, L Tei, L … - Journal of Molecular Medicine, 2009 - Springer
Abstract Disruption of the CD40–CD154 interaction was found to be effective in
the prevention and treatment of several immune-mediated diseases. The
antibody-based strategy of inhibition was in humans limited by platelet ...
Cited by 3 - Related articles - All 3 versions

Suramin inhibits the CD40–CD154 costimulatory interaction: a possible mechanism for …


E Margolles-Clark, MC Jacques-Silva, L … - Biochemical Pharmacology, 2009 - Elsevier
Suramin is a symmetric polysulfonated naphthylamine–benzamide urea derivative
approved for the treatment of trypanosomiasis and onchocerciasis and a known P2
(ATP/UTP purine receptor) antagonist. Here, we report its ability to ...
Cited by 4 - Related articles - All 2 versions

Shipment of Human Islets for Transplantation.


H Ichii, Y Sakuma, A Pileggi, C Fraker, A … - American Journal of Transplantation, 2007 - ccmjournal.org
The use of regional human islet cell processing centers (ICPC) supporting
distant clinical islet transplantation programs (CITP) has proven successful in
recent clinical trials. Standardization of islet shipping protocols is ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Therapeutic peptidomimetic strategies for autoimmune diseases: costimulation blockade


SD Allen, SV Rawale, CC Whitacre, PT … - J Pept Res, 2005 - interscience.wiley.com
Abstract: Cognate interactions between immune effector cells and
antigen-presenting cells (APCs) govern immune responses. Specific signals occur
between the T-cell receptor peptide and APCs and nonspecific signals ...
Cited by 24 - Related articles - All 3 versions

CD40-ligand-dependent induction of COX-2 gene expression in endothelial cells by activated …


BA Mosheimer, NC Kaneider, C Feistritzer, A … - Blood Coagulation & Fibrinolysis, 2005 - journals.lww.com
Increasing evidence shows the importance of platelet– endothelial cell
interactions in the progression of atherosclerosis. Platelets contribute to
coronary events both as major components of thrombi and as a triggering ...
Cited by 13 - Related articles - All 5 versions

Novel CD40: CD154 binding interruptor compounds and use thereof to treat immunological …


Z Zheng, MB Carter, YS Liao, L Sun, L … - US Patent App. 11/701,983, 2007 - Google Patents
US 2007/0249682 Al Oct. 25, 2007 SUMMARY OF THE INVENTION [0009] The present
invention provides novel compounds, other than anti-CD154 antibodies and soluble
CD40 or CD40 fusion proteins, that specifically bind GDI54 and interrupt ...
Cited by 2 - Related articles - All 4 versions


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