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Scholar Results 1 - 10 of about 101 related to Castellano: Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic.... (0.09 sec) 

Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by …


JM Castellano, VM Navarro, R Fernández- … - Diabetes, 2006 - Am Diabetes Assoc
Hypogonadotropism is a common feature of uncontrolled diabetes, for which the
ultimate mechanism remains to be elucidated. Kisspeptins, ligands of G
protein–coupled receptor 54 (GPR54) encoded by the KiSS-1 gene, have ...
Cited by 41 - Related articles - BL Direct - All 5 versions

KiSS-1 Neurones Are Direct Targets for Leptin in the ob/ob Mouse.


JT Smith, BV Acohido, DK Clifton, RA Steiner - Journal of neuroendocrinology, 2006 - ppv.ovid.com
*Department of Physiology and Biophysics, University of Washington, Seattle,
Washington, USA. ... †Department of Obstetrics and Gynecology, University of
Washington, Seattle, Washington, USA. ... Correspondence to: Professor ...
Cited by 83 - Related articles - BL Direct - All 6 versions

Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the …

- endojournals.org
JM Castellano, VM Navarro, R Fernandez- … - Endocrinology, 2005 - Endocrine Soc
Activation of the gonadotropic axis critically depends on sufficient body energy
stores, and conditions of negative energy balance result in lack of puberty
onset and reproductive failure. Recently, KiSS-1 gene-derived kisspeptin, ...
Cited by 109 - Related articles - BL Direct - All 6 versions

Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: …

- endojournals.org
RM Luque, RD Kineman, M Tena-Sempere - Endocrinology, 2007 - Endocrine Soc
It is well established that reproductive function is metabolically gated.
However, the mechanisms whereby energy stores and metabolic cues influence
fertility are yet to be completely deciphered. Recently, the hypothalamic ...
Cited by 25 - Related articles - BL Direct - All 7 versions

Effects of single or repeated intravenous administration of kisspeptin upon dynamic LH …

- endojournals.org
S Tovar, MJ Vazquez, VM Navarro, R … - Endocrinology, 2006 - Endocrine Soc
The ability of kisspeptins, ligands of the G protein-coupled receptor 54, to
potently elicit LH secretion is now undisputed. Yet, most of the pharmacological
characterization of their gonadotropin-releasing effects has been conducted ...
Cited by 25 - Related articles - BL Direct - All 4 versions

Expression of KiSS-1 in rat ovary: putative local regulator of ovulation?

- endojournals.org
JM Castellano, M Gaytan, J Roa, E Vigo, VM … - Endocrinology, 2006 - Endocrine Soc
Kisspeptins, the products of KiSS-1 gene, and their receptor, GPR54, have
recently emerged as essential gatekeepers of reproduction, mainly through
regulation of GnRH secretion at the hypothalamus. However, the profound ...
Cited by 33 - Related articles - BL Direct - All 4 versions

The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction

- washington.edu [PDF] 
SM Popa, DK Clifton, RA Steiner, 2008 - Annual Reviews
Neurons that produce gonadotropin-releasing hormone (GnRH) reside in the basal
forebrain and drive reproductive function in mammals. Understanding the
circuitry that regulates GnRH neurons is fundamental to comprehending the ...
Cited by 43 - Related articles - BL Direct - All 6 versions

Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular …

- endojournals.org
AM Rometo, SJ Krajewski, M Lou Voytko, NE … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Objectives: Our objective was to map the location of neurons expressing
kisspeptin gene (KiSS-1) transcripts in the human hypothalamus and determine
whether menopause is associated with changes in the size and gene ...
Cited by 44 - Related articles - BL Direct - All 4 versions

KiSS-1 and reproduction: focus on its role in the metabolic regulation of fertility


M Tena-Sempere - Neuroendocrinology, 2006 - content.karger.com
Unraveling of the master role of kisspeptins, the products of the KiSS-1 gene,
and their receptor, GPR54, in the control of reproduction has been a major
breakthrough in contemporary neuroendocrinology. Indeed, since the ...
Cited by 36 - Related articles - BL Direct - All 6 versions

Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene

- pnas.org
X d'Anglemont de Tassigny, LA Fagg, JPC … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
The G protein-coupled receptor GPR54 (AXOR12, OT7T175) is central to acquisition
of reproductive competency in mammals. Peptide ligands (kisspeptins) for this
receptor are encoded by the Kiss1 gene, and administration of exogenous ...
Cited by 67 - Related articles - BL Direct - All 10 versions


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