JM Castellano, VM Navarro, R Fernández- … - Diabetes, 2006 - Am Diabetes Assoc Hypogonadotropism is a common feature of uncontrolled diabetes, for which the
ultimate mechanism remains to be elucidated. Kisspeptins, ligands of G
protein–coupled receptor 54 (GPR54) encoded by the KiSS-1 gene, have ... Cited by 41 - Related articles - BL Direct - All 5 versions
JT Smith, BV Acohido, DK Clifton, RA Steiner - Journal of neuroendocrinology, 2006 - ppv.ovid.com *Department of Physiology and Biophysics, University of Washington, Seattle,
Washington, USA. ... †Department of Obstetrics and Gynecology, University of
Washington, Seattle, Washington, USA. ... Correspondence to: Professor ... Cited by 83 - Related articles - BL Direct - All 6 versions
- ►endojournals.org JM Castellano, VM Navarro, R Fernandez- … - Endocrinology, 2005 - Endocrine Soc Activation of the gonadotropic axis critically depends on sufficient body energy
stores, and conditions of negative energy balance result in lack of puberty
onset and reproductive failure. Recently, KiSS-1 gene-derived kisspeptin, ... Cited by 109 - Related articles - BL Direct - All 6 versions
- ►endojournals.org RM Luque, RD Kineman, M Tena-Sempere - Endocrinology, 2007 - Endocrine Soc It is well established that reproductive function is metabolically gated.
However, the mechanisms whereby energy stores and metabolic cues influence
fertility are yet to be completely deciphered. Recently, the hypothalamic ... Cited by 25 - Related articles - BL Direct - All 7 versions
- ►endojournals.org S Tovar, MJ Vazquez, VM Navarro, R … - Endocrinology, 2006 - Endocrine Soc The ability of kisspeptins, ligands of the G protein-coupled receptor 54, to
potently elicit LH secretion is now undisputed. Yet, most of the pharmacological
characterization of their gonadotropin-releasing effects has been conducted ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►endojournals.org JM Castellano, M Gaytan, J Roa, E Vigo, VM … - Endocrinology, 2006 - Endocrine Soc Kisspeptins, the products of KiSS-1 gene, and their receptor, GPR54, have
recently emerged as essential gatekeepers of reproduction, mainly through
regulation of GnRH secretion at the hypothalamus. However, the profound ... Cited by 33 - Related articles - BL Direct - All 4 versions
- ►washington.edu [PDF] SM Popa, DK Clifton, RA Steiner, 2008 - Annual Reviews Neurons that produce gonadotropin-releasing hormone (GnRH) reside in the basal
forebrain and drive reproductive function in mammals. Understanding the
circuitry that regulates GnRH neurons is fundamental to comprehending the ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►endojournals.org AM Rometo, SJ Krajewski, M Lou Voytko, NE … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Objectives: Our objective was to map the location of neurons expressing
kisspeptin gene (KiSS-1) transcripts in the human hypothalamus and determine
whether menopause is associated with changes in the size and gene ... Cited by 44 - Related articles - BL Direct - All 4 versions
M Tena-Sempere - Neuroendocrinology, 2006 - content.karger.com Unraveling of the master role of kisspeptins, the products of the KiSS-1 gene,
and their receptor, GPR54, in the control of reproduction has been a major
breakthrough in contemporary neuroendocrinology. Indeed, since the ... Cited by 36 - Related articles - BL Direct - All 6 versions
- ►pnas.org X d'Anglemont de Tassigny, LA Fagg, JPC … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences The G protein-coupled receptor GPR54 (AXOR12, OT7T175) is central to acquisition
of reproductive competency in mammals. Peptide ligands (kisspeptins) for this
receptor are encoded by the Kiss1 gene, and administration of exogenous ... Cited by 67 - Related articles - BL Direct - All 10 versions