- ►diabetesjournals.org SK Das, WS Chu, TC Hale, X Wang, RL Craig, … - Diabetes, 2006 - Am Diabetes Assoc Linkage of type 2 diabetes to chromosome 1q21-q23 is well replicated across
populations. In an initial 50-kb marker map (580 markers) across the linked
region, one of the two strongest associations observed in Utah Caucasians ... Cited by 12 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org SK Das, W Chu, Z Zhang, SJ Hasstedt, SC … - Diabetes, 2004 - Am Diabetes Assoc Genome-wide scans in multiple populations have identified chromosome 1q21-q24 as
one susceptibility region for type 2 diabetes. To map the susceptibility genes,
we first placed a dense single nucleotide polymorphism (SNP) map across the ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org WS Chu, SK Das, H Wang, JC Chan, P Deloukas … - Diabetes, 2007 - Am Diabetes Assoc Activating transcription factor 6 (ATF6) is located within the region of linkage
to type 2 diabetes on chromosome 1q21-q23 and is a key activator of the
endoplasmic reticulum stress response. We evaluated 78 single nucleotide ... Cited by 8 - Related articles - BL Direct - All 12 versions
[CITATION] Meta-analysis of 3,000 single nucleotide polymorphisms from chromosome 1q in samples from …
SC Elbein, X Wang, MA Karim, WS Chu, KD … - BMC Medical Genetics, 2006 - biomedcentral.com Betacellulin is a member of the epidermal growth factor family, expressed at the
highest levels predominantly in the pancreas and thought to be involved in islet
neogenesis and regeneration. Nonsynonymous coding variants were reported to ... Cited by 4 - Related articles - Cached - All 9 versions
[CITATION] Strong association of intragenic SNPs with type 2 diabetes in the 152 megabase region of …
M Fu, M Sabra, C Damcott, TI Pollini, S Ott, K … - American Society of Human Genetics 54th Meeting …, 2004 Cited by 3 - Related articles
- ►diabetesjournals.org M Fu, CM Damcott, M Sabra, TI Pollin, SH Ott, … - Diabetes, 2004 - Am Diabetes Assoc Calsequestrin (CASQ)1 is involved in intracellular storage and release of
calcium, a process that has been shown to mediate glucose transport in muscle.
Its gene, CASQ1, is encoded on chromosome 1q21, a region that has been ... Cited by 12 - Related articles - BL Direct - All 5 versions
H Wang, W Chu, SK Das, Z Zheng, SJ … - Molecular Genetics and Metabolism, 2003 - Elsevier The retinoid-related orphan receptor γ (RORC) is a member of the nuclear
hormone superfamily which maps to the 1q21-q23 region. Linkage of type 2
diabetes (T2DM) to this region is well replicated. Several factors argue ... Cited by 13 - Related articles - All 4 versions
SK Das, SC Elbein - Current Diabetes Reports, 2007 - Springer The unbiased approach of genome-wide linkage analysis has shown evidence for
linkage of type 2 diabetes mel- litus to the chromosome 1q21-25 region in at
least eight independent studies. More than 26 candidate genes have already ... Cited by 14 - Related articles - BL Direct - All 2 versions
SC Elbein - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com Purpose of review Populations of direct African ancestry have much greater
genetic diversity than do other populations. African– American populations
exhibit twice the prevalence of type 2 diabetes as compared with their ... Cited by 14 - Related articles - BL Direct - All 5 versions
