C Zhang, L Qi, DJ Hunter, JB Meigs, JAE Manson, RM … - Diabetes, 2006 - Am Diabetes Assoc Emerging evidence indicates that variation in the transcription factor 7-like 2 (TCF7L2) gene
may play a role in the pathogenesis of type 2 diabetes. In a prospective, nested, case-control
study (n = 3,520) within the Nurses' Health Study (687 type 2 diabetic case and 1,051 ... Cited by 115 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org LJ Scott, LL Bonnycastle, CJ Willer, AG Sprau, AU … - Diabetes, 2006 - Am Diabetes Assoc Transcription factor 7-like 2 (TCF7L2) is part of the Wnt signaling pathway. Genetic variants within
TCF7L2 on chromosome 10q were recently reported to be associated with type 2 diabetes in
Icelandic, Danish, and American (US) samples. We previously observed a modest ... Cited by 139 - Related articles - BL Direct - All 9 versions
CJ Groves, E Zeggini, J Minton, TM Frayling, MN … - Diabetes, 2006 - Am Diabetes Assoc Recent data suggest that common variation in the transcription factor 7-like 2 (TCF7L2) gene
is associated with type 2 diabetes. Evaluation of such associations in independent samples provides
necessary replication and a robust assessment of effect size. Using four TCF7L2 single ... Cited by 134 - Related articles - BL Direct - All 5 versions
S Cauchi, D Meyre, C Dina, H Choquet, C Samson, S … - Diabetes, 2006 - Am Diabetes Assoc Recently, the transcription factor 7-like 2 (TCF7L2) gene has been associated with type 2 diabetes
in subjects of European origin in the DeCode study. We genotyped the two most associated variants
(rs7903146 and rs12255372) in 2,367 French type 2 diabetic subjects and in 2,499 ... Cited by 150 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org CM Damcott, TI Pollin, LJ Reinhart, SH Ott, H Shen, KD … - Diabetes, 2006 - Am Diabetes Assoc Transcription factor 7-like 2 (TCF7L2) regulates genes involved in cell proliferation and
differentiation. The TCF7L2 gene is located on chromosome 10q25 in a region of replicated linkage
to type 2 diabetes. Recently, a microsatellite marker in intron 3 (DG10S478) and five ... Cited by 151 - Related articles - BL Direct - All 4 versions
- ►rug.nl [PDF] JV van Vliet-Ostaptchouk, R Shiri-Sverdlov, A … - Diabetologia, 2007 - Springer Page 1. SHORT COMMUNICATION Association of variants of transcription factor 7-like 2 (TCF7L2)
with susceptibility to type 2 diabetes in the Dutch Breda cohort JV van Vliet-Ostaptchouk & R.
Shiri-Sverdlov & A. Zhernakova & E. Strengman & TW van Haeften & ... Cited by 69 - Related articles - BL Direct - All 5 versions
R Saxena, L Gianniny, NP Burtt, V Lyssenko, C … - Diabetes, 2006 - Am Diabetes Assoc Recently, common noncoding variants in the TCF7L2 gene were strongly associated with increased
risk of type 2 diabetes in samples from Iceland, Denmark, and the US We genotyped 13 single
nucleotide polymorphisms (SNPs) across TCF7L2 in 8,310 individuals in family-based ... Cited by 160 - Related articles - BL Direct - All 4 versions
- ►pubget.com [PDF] SE Humphries, D Gable, JA Cooper, H Ireland, JW … - Journal of Molecular …, 2006 - Springer Page 1. ORIGINAL ARTICLE Common variants in the TCF7L2 gene and predisposition
to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and
women Steve E. Humphries & David Gable & Jackie A. Cooper & ... Cited by 88 - Related articles - BL Direct - All 8 versions
- ►ccmb.res.in [PDF] GR Chandak, CS Janipalli, S Bhaskar, SR Kulkarni, P … - Diabetologia, 2007 - Springer Abstract Aims and hypothesis India has the greatest number of diabetic subjects in any one
country, but the genetic basis of type 2 diabetes mellitus in India is poorly understood. Common
non-coding variants in the transcription factor 7-like 2gene (TCF7L2) have recently been ... Cited by 85 - Related articles - BL Direct - All 5 versions
- ►nih.gov JC Florez, KA Jablonski, N Bayley, TI Pollin, … - The New England …, 2006 - nejm.highwire.org Results Over an average period of three years, participants with the risk-conferring TT genotype
at rs7903146 were more likely to have progression from impaired glucose tolerance to diabetes
than were CC homozygotes (hazard ratio, 1.55; 95 percent confidence interval, 1.20 to ... Cited by 257 - Related articles - BL Direct - All 8 versions
