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Scholar Results 1 - 10 of about 101 related to Fex: β-Cell lipases and insulin secretion. (0.12 sec) 

β-Cell lipases and insulin secretion

- diabetesjournals.org
M Fex, S Lucas, MS Winzell, B Ahrén, C Holm … - Diabetes, 2006 - Am Diabetes Assoc
Lipids have been implicated in β-cell stimulus-secretion coupling. Thus,
lipases in β-cells would be required to generate coupling factors from
intracellular lipids. Indeed, we found that glucose stimulates lipolysis in ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Function of hormone-sensitive lipase in diacylglycerol–protein kinase C pathway


H Kanehara, J Suzuki, Y Zenimaru, S … - Diabetes research and clinical practice, 2004 - Elsevier
To explore the functional effects of hormone-sensitive lipase (HSL) in
diacylglycerol (DAG) metabolism, Chinese hamster ovary cells were stably
transfected with rat HSL cDNA (wt-HSL), inactive mutant S423A-HSL cDNA ...
Cited by 7 - Related articles - All 8 versions

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit …

- endocrinology-journals.org
M Fex, N Wierup, MD Nitert, M Ristow, H … - Journal of Endocrinology, 2007 - Soc Endocrinology
Gene inactivation, using the Cre/LoxP system, is an essential technique in
tissue-specific gene targeting. The rat insulin promoter 2-Cre recombinase
(RIP2-Cre) mouse (also called RIP-Cre or B6.Cg-Tg (Ins2-cre) 25 Mgn/J, ...
Cited by 3 - Related articles - BL Direct - All 2 versions

Malin Fex, Stephanie Lucas, Maria Sörhede Winzell, 2 Bo Ahrén, 2 Cecilia Holm, and …


S Lund, K ATP-sensitive - Diabetes, 2006 - Am Diabetes Assoc
Lipids have been implicated in -cell stimulus-secretion coupling. Thus, lipases
in -cells would be required to generate coupling factors from intracellular
lipids. Indeed, we found that glucose stimulates lipolysis in rodent islets ...
Related articles - All 2 versions

您所在位置: 首页> 期刊> 过刊浏览> 内科学>《 糖尿病学杂志》> 2006 年 12 月 55 卷 12 期> …


M Fex, S Lucas, MS Winzell, B Ahren, C Holm … - journal.shouxi.net
Lipids have been implicated in -cell stimulus-secretion coupling. Thus, lipases
in -cells would be required to generate coupling factors from intracellular
lipids. Indeed, we found that glucose stimulates lipolysis in rodent islets ...
Related articles - Cached

Glucose-stimulated insulin secretion correlates with β-cell lipolysis


MS Winzell, K Ström, C Holm, B Ahrén - Nutrition, Metabolism and Cardiovascular Diseases, 2006 - Elsevier
Lipids are needed for optimal glucose-stimulated insulin secretion (GSIS), and
long-chain acyl-CoA (LC-CoA) has been suggested as one candidate molecule active
as a lipidic coupling factor. LC-CoAs may be available to the β-cell via ...
Cited by 5 - Related articles - All 5 versions

Lipases in the pancreatic beta-cell: implications for insulin secretion


M Fex, H Mulder - Biochemical Society Transactions, 2008 - biochemsoctrans.org
Lipids have been implicated in β-cell stimulus–secretion coupling. In such a
role, lipases in β-cells would be required to generate lipid coupling factors.
We have shown previously that glucose stimulates lipolysis in rodent ...
Related articles - Cached - All 3 versions

Neutral lipid storage disease: genetic disorders caused by mutations in adipose …


M Schweiger, A Lass, R Zimmermann, TO … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
Neutral lipid storage disease (NLSD) is a group of autosomal recessive disorders
characterized by the excessive accumulation of neutral lipids in multiple
tissues. Recently, two genes, adipose triglyceride lipase (ATGL/PNPLA2) and ...
Related articles - All 3 versions

A Novel Hormone-sensitive Lipase Isoform Expressed in Pancreatic{beta}-Cells


H Lindvall, P Nevsten, K Ström, R Wallenberg … - Journal of Biological Chemistry, 2004 - ASBMB
Hormone-sensitive lipase (HSL) is a key enzyme in fatty acid mobilization in
many cell types. Two isoforms of HSL are known to date, namely HSL adi (84 kDa
in rat) and HSL tes (130 kDa in rat). These are encoded by the same gene, ...
Cited by 22 - Related articles - BL Direct - All 4 versions

[PDF] Molecular Mechanisms of Glucolipotoxicity in Diabetes


M Fex, H Mulder - Biochemical Society Transactions, 2008 - biochemsoctrans.org
Abstract Lipids have been implicated in β-cell stimulus–secretion coupling.
In such a role, lipases in β-cells would be re- quired to generate lipid
coupling factors. We have shown previously that glucose stimulates ...
Related articles - View as HTML


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