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Scholar Results 1 - 10 of about 101 related to Newsholme: Amino acid metabolism, β-cell function, and diabetes. (0.09 sec) 

Amino acid metabolism, β-cell function, and diabetes

- shouxi.net
P Newsholme, L Brennan, K Bender - Diabetes, 2006 - Am Diabetes Assoc
Specific amino acids are known to acutely and chronically regulate insulin
secretion from pancreatic β-cells in vivo and in vitro. Mitochondrial
metabolism is crucial for the coupling of amino acid and glucose ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Role of NADPH oxidase and calcium in cerulein-induced apoptosis: involvement of apoptosis …


JH Yu, KH Kim, H Kim - Annals of the New York Academy of Sciences, 2006 - ingentaconnect.com
Apoptosis linked to oxidative stress has been implicated in pancreatitis. NADPH
oxidase has been considered as a major source of reactive oxygen species (ROS)
during inflammation and apoptosis in pancreatic acinar cells. Recently we ...
Cited by 7 - Related articles - BL Direct - All 6 versions

Amino acid metabolism, insulin secretion and diabetes.


P Newsholme, K Bender, A Kiely, L Brennan - Biochemical Society Transactions, 2007 - ncbi.nlm.nih.gov
In addition to the primary stimulus of glucose, specific amino acids may acutely
and chronically regulate insulin secretion from pancreatic beta-cells in vivo
and in vitro. Mitochondrial metabolism is crucial for the coupling of ...
Cited by 13 - Related articles - BL Direct - All 3 versions

cAMP-mediated signaling normalizes glucose-stimulated insulin secretion in uncoupling …

- endocrinology-journals.org
TS McQuaid, MC Saleh, JW Joseph, A … - Journal of Endocrinology, 2006 - Soc Endocrinology
We investigated whether an increase in cAMP could normalize glucose-stimulated
insulin secretion (GSIS) in uncoupling protein-2 (UCP2) overexpressing (ucp2-OE)
ß-cells. Indices of ß-cell (ß-TC-6f7 cells and rodent islets) function ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Endogenous islet uncoupling protein-2 expression and loss of glucose homeostasis in ob/ …

- endocrinology-journals.org
MC Saleh, MB Wheeler, CB Chan - Journal of Endocrinology, 2006 - Soc Endocrinology
We hypothesized that the loss of glucose homeostasis in ob/ob mice is associated
with upregulation of islet uncoupling protein-2 (UCP2) expression, leading to
impaired glucose-stimulated insulin secretion (GSIS). Changes in glucose ...
Cited by 18 - Related articles - BL Direct - All 3 versions

α-酮戊二酸对脂多糖应激断奶仔猪生长抑制的缓解作用


刘坚, 侯永清, 丁斌鹰, 刘玉兰, 朱惠玲, 王蕾 … - 动物营养学报, 2009 - cqvip.com
试验用大肠杆菌脂多糖(LPS)多次刺激断奶仔猪建立应激模型,研究α-酮戊二酸(AKG)对
断奶仔猪的生长性能和血浆激素水平的影响,探讨AKG能否缓解仔猪应激反应。选用24头健康 ...
Related articles

L-赖氨酸对克隆的胰岛 β 细胞株 INS-1E 细胞的急性作用


刘振平, 张艳玲 - 天津医药, 2008 - cqvip.com
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Related articles - All 2 versions

Analysis of free amino acids in islets of Langerhans by high-performance liquid …


C Yang, X Jiang, L Guo, H Zhang, M Liu - Journal of High Resolution Chromatography - interscience.wiley.com
A simple high-performance liquid chromatographic method with pre-column
derivatization and fluorescence detection was developed and used for the
analysis of free amino acids in islets of Langerhans; 4-chloro-7-nitrobenzo- ...
Related articles - BL Direct - All 4 versions

[PDF] 당뇨병과 산화 스트레스: 미토콘드리아 및 NAD (P) H Oxidase 에 의한 ROS 의 생성과 역할


김상수, 손석만 - 210.101.116.17
발생에 중요한 역할을 하는 것으로 생각된다5). ROS로부터의
세포 또는 조직의 손상은 당뇨병뿐만 아니 라 염증, 노화
관련 변성, 종양의 생성 등과 관련이 있는 것 으로 ...
Related articles - View as HTML - All 4 versions

Insights into the critical role of NADPH oxidase (s) in the normal and dysregulated pancreatic …


P Newsholme, D Morgan, E Rebelato, HC … - Diabetologia - Springer
Abstract It is now widely accepted that reactive oxygen species (ROS) contribute
to cell and tissue dysfunction and damage in diabetes. The source of ROS in the
insulin secreting pancreatic beta cells has traditionally been considered ...
Related articles - All 2 versions


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