- ►shouxi.net P Newsholme, L Brennan, K Bender - Diabetes, 2006 - Am Diabetes Assoc Specific amino acids are known to acutely and chronically regulate insulin
secretion from pancreatic β-cells in vivo and in vitro. Mitochondrial
metabolism is crucial for the coupling of amino acid and glucose ... Cited by 9 - Related articles - BL Direct - All 4 versions
JH Yu, KH Kim, H Kim - Annals of the New York Academy of Sciences, 2006 - ingentaconnect.com Apoptosis linked to oxidative stress has been implicated in pancreatitis. NADPH
oxidase has been considered as a major source of reactive oxygen species (ROS)
during inflammation and apoptosis in pancreatic acinar cells. Recently we ... Cited by 7 - Related articles - BL Direct - All 6 versions
P Newsholme, K Bender, A Kiely, L Brennan - Biochemical Society Transactions, 2007 - ncbi.nlm.nih.gov In addition to the primary stimulus of glucose, specific amino acids may acutely
and chronically regulate insulin secretion from pancreatic beta-cells in vivo
and in vitro. Mitochondrial metabolism is crucial for the coupling of ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►endocrinology-journals.org TS McQuaid, MC Saleh, JW Joseph, A … - Journal of Endocrinology, 2006 - Soc Endocrinology We investigated whether an increase in cAMP could normalize glucose-stimulated
insulin secretion (GSIS) in uncoupling protein-2 (UCP2) overexpressing (ucp2-OE)
ß-cells. Indices of ß-cell (ß-TC-6f7 cells and rodent islets) function ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org MC Saleh, MB Wheeler, CB Chan - Journal of Endocrinology, 2006 - Soc Endocrinology We hypothesized that the loss of glucose homeostasis in ob/ob mice is associated
with upregulation of islet uncoupling protein-2 (UCP2) expression, leading to
impaired glucose-stimulated insulin secretion (GSIS). Changes in glucose ... Cited by 18 - Related articles - BL Direct - All 3 versions
C Yang, X Jiang, L Guo, H Zhang, M Liu - Journal of High Resolution Chromatography - interscience.wiley.com A simple high-performance liquid chromatographic method with pre-column
derivatization and fluorescence detection was developed and used for the
analysis of free amino acids in islets of Langerhans; 4-chloro-7-nitrobenzo- ... Related articles - BL Direct - All 4 versions
김상수, 손석만 - 210.101.116.17 발생에 중요한 역할을 하는 것으로 생각된다5). ROS로부터의
세포 또는 조직의 손상은 당뇨병뿐만 아니 라 염증, 노화
관련 변성, 종양의 생성 등과 관련이 있는 것 으로 ... Related articles - View as HTML - All 4 versions
P Newsholme, D Morgan, E Rebelato, HC … - Diabetologia - Springer Abstract It is now widely accepted that reactive oxygen species (ROS) contribute
to cell and tissue dysfunction and damage in diabetes. The source of ROS in the
insulin secreting pancreatic beta cells has traditionally been considered ... Related articles - All 2 versions