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Scholar Results 1 - 10 of about 101 related to Reimann: Signaling mechanisms underlying the release of glucagon-like peptide 1. (0.14 sec) 

Signaling mechanisms underlying the release of glucagon-like peptide 1


F Reimann, PS Ward, FM Gribble - Diabetes, 2006 - Am Diabetes Assoc
Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response
to a range of nutrients, hormones, and neurotransmitters. Its potency as an
insulin secretagogue has led to pharmaceutical interest in developing ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Characterization and functional role of voltage gated cation conductances in the glucagon- …


F Reimann, M Maziarz, G Flock, AM Habib, DJ … - The Journal of Physiology, 2005 - Physiological Soc
Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response
to nutrient ingestion. It is currently under therapeutic evaluation because it
enhances insulin secretion in type 2 diabetes. Previous studies using the ...
Cited by 9 - Related articles - BL Direct - All 11 versions

Possible role of PEPT1 in gastrointestinal hormone secretion


K Matsumura, T Miki, T Jhomori, T Gonoi, S … - Biochemical and Biophysical Research …, 2005 - Elsevier
Oligopeptides originating from ingested meal stimulate the secretion of various
gastrointestinal hormones, but the mechanism is unknown. In this study, we show
that transfection of oligopeptide transporter 1 (PEPT1) in STC-1 cells, a ...
Cited by 5 - Related articles - All 4 versions

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells


F Reimann, L Williams, G da Silva Xavier, GA … - Diabetologia, 2004 - Springer
Aims/hypothesis. Glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are
secreted from enteroendocrine L cells in response to nutrient ingestion. As
glutamine is an important metabolic fuel for the gut, the aim of this study ...
Cited by 23 - Related articles - BL Direct - All 6 versions

Insulin-secreting L-cells for the treatment of insulin-dependent diabetes

- nih.gov
H Bara, A Sambanis - Biochemical and biophysical research communications, 2008 - Elsevier
Cell-based treatments for insulin-dependent diabetes (IDD) may provide more
physiologic regulation of blood glucose levels than daily insulin injections,
thereby reducing the occurrence of secondary complications associated with ...
Cited by 3 - Related articles - All 3 versions

Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell


GE Lim, GJ Huang, N Flora, D LeRoith, CJ … - Endocrinology, 2009 - Endocrine Soc
Insulin resistance and type 2 diabetes mellitus are associated with impaired
postprandial secretion of glucagon-like peptide-1 (GLP-1), a potent
insulinotropic hormone. The direct effects of insulin and insulin ...
Cited by 4 - Related articles - All 3 versions

Cyclic AMP triggers glucagon-like peptide-1 secretion from the GLUTag enteroendocrine cell …


AK Simpson, PS Ward, KY Wong, GJ Collord, … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis To investigate the pathways by which cyclic AMP (cAMP)
stimulates glucagon-like peptide-1 (GLP-1) secretion, using the GLUTag
enteroendocrine cell line. Materials and methods GLP-1 release from GLUTag ...
Cited by 10 - Related articles - BL Direct - All 3 versions

Glucose sensing in L cells: a primary cell study

- nih.gov
F Reimann, AM Habib, G Tolhurst, HE Parker, … - Cell Metabolism, 2008 - Elsevier
Glucagon-like peptide-1 (GLP-1) is an enteric hormone that stimulates insulin
secretion and improves glycaemia in type 2 diabetes. Although GLP-1-based
treatments are clinically available, alternative strategies to increase ...
Cited by 10 - Related articles - All 11 versions

Protein hydrolysates stimulate proglucagon gene transcription in intestinal endocrine cells …


JC Gevrey, M Malapel, J Philippe, G Mithieux, … - Diabetologia, 2004 - Springer
Aims/hypothesis. Protein hydrolysates (peptones) in- crease not only
glucagon-like peptide-1 (GLP-1) se- cretion but also transcription of the
proglucagon (PG) gene in the intestine. The critical physiological roles of ...
Cited by 19 - Related articles - BL Direct - All 4 versions

Glucose-stimulated insulin secretion is not obligatorily linked to an increase in O2 …

- physiology.org
KK Papas, MAC Jarema - American Journal of Physiology- Endocrinology And …, 1998 - Am Physiological Soc
We investigated the effects of glucose on the rates of oxygen consumption (OCR)
and insulin secretion (ISR) by HC9 cells derived from mouse pancreatic islets
with -cell hyperplasia. Our results demonstrate that the OCR by HC9 cells ...
Cited by 12 - Related articles - BL Direct - All 5 versions


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