- ►diabetesjournals.org SJ Persaud, D Muller, VD Belin, I Kitsou-Mylona, H … - Diabetes, 2007 - Am Diabetes Assoc The roles played by arachidonic acid and its cyclooxygenase (COX)-generated and lipoxygenase
(LOX)-generated metabolites have been studied using rodent islets and insulin-secreting cell lines,
but very little is known about COX ... Cited by 12 - Related articles - BL Direct - All 5 versions
M Chen, ZD Yang, KM Smith, JD Carter, JL Nadler - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Beta cell inflammation and cytokine-induced toxicity are central to
autoimmune dia- betes development. Lipid mediators generated upon lipo- xygenase (LO) activation can
participate in inflammatory ... Cited by 15 - Related articles - All 3 versions
- ►physiology.org CS Nunemaker, M Chen, H Pei, SD … - American Journal of …, 2008 - Am Physiological Soc Inflammation is a key pathological process in the progression of atherosclerosis and type 2
diabetes. 12/15-lipoxygenase (12-LO), an enzyme involved in fatty acid metabolism, may contribute to
inflammatory damage triggered by ... Cited by 1 - Related articles - All 3 versions
SJ Persaud, D Muller, VD Belin, A … - … of Physiology and …, 2007 - informahealthcare.com Arachidonic acid (AA) is generated in pancreatic β-cells through the activation of Ca 2+ -dependent
cytosolic phospholipase A 2 (cPLA 2 ) and the consequent hydrolysis of membrane phospholipids in the
sn-2 position of the ... Cited by 1 - Related articles - BL Direct - All 4 versions
PM Jones, CJ Burns, VD Belin, HM Roderigo-Milne, SJ … - Diabetes, 2004 - Am Diabetes Assoc Cytosolic phospholipase A 2 (cPLA 2 ) comprises a widely expressed family of enzymes, some members
of which have the properties required of signal transduction elements in electrically excitable
cells. Thus, α- and β-isoforms of ... Cited by 9 - Related articles - BL Direct - All 4 versions
MH Nathan, SB Pek - Advances in prostaglandin, thromboxane, and …, 1991 - ncbi.nlm.nih.gov 1: Adv Prostaglandin Thromboxane Leukot Res. 1991;21A:17-20. 5-Lipoxygenase mRNA is expressed
in rat pancreatic islets. Nathan MH, Pek SB. University of Michigan, Ann Arbor 48109-0678.
Mesh Terms: Animals; Arachidonate 5-Lipoxygenase/biosynthesis ... Cited by 2 - Related articles - All 2 versions
[CITATION] Reduced macrophage infiltration in visceral adipose tissue of 12-lipoxygenase …
