- ►shouxi.net JA Vincent, S Mohr - Diabetes, 2007 - Am Diabetes Assoc The proinflammatory cytokine, interleukin (IL)-1β, is known to induce vascular
dysfunction and cell death. We investigated the role of IL-1β and caspase-1
(the enzyme that produces it) in diabetes-induced degeneration of retinal ... Cited by 19 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org TS Kern, CM Miller, Y Du, L Zheng, S Mohr, … - Diabetes, 2007 - Am Diabetes Assoc Pharmacologic treatment of diabetic retinopathy via eyedrops could have
advantages but has not been successful to date. We explored the effect of
topical Nepafenac, an anti-inflammatory drug known to reach the retina when ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►iovs.org RJ Walker, JJ Steinle - Investigative Ophthalmology & Visual Science, 2007 - ARVO RESULTS. Isoproterenol treatment significantly decreased protein levels of iNOS,
TNF- , and IL-1B, in rMC-1 cells cultured in high glucose as early as 1 hour,
compared with cells receiving no treatment. PGE2 content was also reduced ... Cited by 3 - Related articles - BL Direct - All 2 versions
- ►nih.gov - Free from Publisher RA Kowluru, S Odenbach - British Journal of Ophthalmology, 2004 - bjo.bmj.com Results: High glucose increased IL-1β expression by 60% compared with cells
incubated in 5 mM glucose (p<0.05). Incubation of cells with IL-1β increased NO
levels by about 80% and activated NF-κB by 40%. In the same cells ... Cited by 36 - Related articles - BL Direct - All 9 versions
- ►iovs.org LL Kusner, VP Sarthy, S Mohr - Investigative ophthalmology & visual science, 2004 - ARVO PURPOSE. A recent study demonstrated that retinal Müller cells undergo
hyperglycemia-induced apoptosis in vitro. Translocation of
glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from the cytosol to the ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org JV Busik, S Mohr, MB Grant - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Glucose consumption of HRECs, human retinal
pigment epithelial cells (HRPEs), and human Müller cells (HMCs) under elevated
glucose conditions was measured and compared with cytokine treatment. ... Cited by 16 - Related articles - All 5 versions
- ►iovs.org RA Kowluru, S Odenbach - Investigative ophthalmology & visual science, 2004 - ARVO RESULTS. The number of TUNEL-positive capillary cells in the retinal
microvessels obtained from normal rats that received intravitreal injection of
IL-1ß was increased by more than threefold and that of acellular ... Cited by 33 - Related articles - BL Direct - All 3 versions
TS KERN, R KOWLURU, RL ENGERMAN - Lessons from animal diabetes VI: 75th anniversary of …, 1996 - books.google.com Dog and rat models of diabetic retinopathy TIMOTHY S. KERN, RENU KOWLURU, AND
RONALD L. ENGERMAN Department of Ophthalmology and Visual Science, University of
Wisconsin-Madison, Madison, Wisconsin 53706, USA. Key words: dog, rat, ... Cited by 8 - Related articles
- ►shouxi.net JK Krady, A Basu, CM Allen, Y Xu, KF … - Diabetes, 2005 - Am Diabetes Assoc Diabetes leads to vascular leakage, glial dysfunction, and neuronal apoptosis
within the retina. The goal of the studies reported here was to determine the
role that retinal microglial cells play in diabetic retinopathy and assess ... Cited by 81 - Related articles - All 10 versions
S Mohr - eid, 2004 - informahealthcare.com Recent studies have demonstrated that diabetic retinopathy has several
characteristics of a chronic inflammatory disease, such as increased nitric
oxide production, intracellular adhesion molecule-1 upregulation, ... Cited by 20 - Related articles - All 5 versions
