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Scholar Results 1 - 10 of about 101 related to Gao: Involvement of apolipoprotein E in excess fat accumulation and insulin resistance. (0.23 sec) 

Involvement of apolipoprotein E in excess fat accumulation and insulin resistance


J Gao, H Katagiri, Y Ishigaki, T Yamada, T Ogihara, J … - Diabetes, 2007 - Am Diabetes Assoc
Although apolipoprotein E (apoE) is well known to play a major role in lipid metabolism, its role
in glucose and energy homeostasis remains unclear. Herein, we established apoE-deficient
genetically obese Ay (apoE −/− ;Ay/+) mice. ApoE deficiency in Ay mice prevented the ...
Cited by 26 - Related articles - BL Direct - All 4 versions

Endogenous apoE expression modulates adipocyte triglyceride content and …

- diabetesjournals.org
ZH Huang, CA Reardon, T Mazzone - Diabetes, 2006 - Am Diabetes Assoc
Apolipoprotein E (apoE) is highly expressed in adipose tissue and adipocytes in which its expression
is regulated by peroxisome proliferator–activated receptor (PPAR)-γ agonists and tumor necrosis
factor–α. There is, however, no information regarding a role for endogenous apoE in ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Defective Lipid Delivery Modulates Glucose Tolerance and Metabolic Response to …

- diabetesjournals.org
SM Hofmann, D Perez-Tilve, TM Greer, BA Coburn, E … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Plasma TG clearance and lipid uptake by adipose tissue were impaired, whereas
glucose tolerance was improved in control diet–fed apoE −/− mice compared with apoE +/+ mice
after an oral lipid load. Fat mass was reduced in apoE −/− mice compared with apoE +/+ ...
Cited by 8 - Related articles - BL Direct - All 4 versions

VLDL induces adipocyte differentiation in ApoE-dependent manner

- ahajournals.org
T Chiba, T Nakazawa, K Yui, E Kaneko, K … - … , and vascular biology, 2003 - Am Heart Assoc
Methods and Results— When fed a high-fat, high-cholesterol diet, ob/ob;apoE -/- mice did not
show increased body weight or an increased amount of adipose tissue in spite of increased plasma
VLDL levels, whereas ob/ob mice showed an increased body weight and amount of ...
Cited by 34 - Related articles - BL Direct - All 7 versions

Involvement of Apolipoprotein E in Excess Fat Accumulation and Insulin …


JGH Katagiri, Y Ishigaki, T Yamada, T Ogihara, JIKUY … - 糖尿病学杂志, 2007 - journal.shouxi.net
【摘要】 Although apolipoprotein E (apoE) is well known to play a major role in lipid
metabolism, its role in glucose and energy homeostasis remains unclear. Herein, we established
apoE-deficient genetically obese Ay (apoE–/–;Ay/+) mice. ApoE deficiency in Ay mice ...
Related articles - Cached

Nutritional regulation of adipose tissue apolipoprotein E expression

- physiology.org
ZH Huang, RM Luque, RD Kineman, T … - American Journal of …, 2007 - Am Physiological Soc
Apolipoprotein E (apoE) is a multifunctional protein that is highly expressed in human and murine
adipose tissue. Endogenous adipocyte apoE expression influences adipocyte triglyceride turnover
and modulates the expression of genes involved in lipid synthesis and oxidation. We now ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Divergent Effects of Peroxisome Proliferator-activated Receptor γ Agonists and …


L Yue, N Rasouli, G Ranganathan, PA Kern, T … - Journal of Biological …, 2004 - ASBMB
ApoE is expressed in multiple mammalian cell types in which it supports cellular differentiated
function. In this report we demonstrate that apoE expression in adipocytes is regulated by factors
involved in modulating systemic insulin sensitivity. Systemic treatment with pioglitazone ...
Cited by 26 - Related articles - BL Direct - All 4 versions

Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice


I Karagiannides, R Abdou, A Tzortzopoulou, PJ … - FEBS …, 2008 - interscience.wiley.com
Obesity is a central feature of the metabolic syndrome and is associated with increased risk for
insulin resistance and type II diabetes. Here, we investigated the contribution of human apoliprotein
E3 and mouse apoliprotein E to the development of diet-induced obesity in response to ...
Cited by 2 - Related articles - All 3 versions

Differential modulation of diet-induced obesity and adipocyte functionality by …


JM Arbones-Mainar, LA Johnson, MK Altenburg, … - International Journal of …, 2008 - nature.com
After 8 weeks on a Western-type high-fat diet, male APOE4 mice displayed impaired tolerance
to glucose and fat overload compared with APOE3 mice. Subcutaneous fat tissues in APOE4
and APOE3 mice after high fat feeding were not different. In contrast, although epididymal ...
Cited by 3 - Related articles - All 3 versions

[PDF] Obesity modulates the association among APOE genotype, insulin, and glucose in …


R Elosua, S Demissie, LA Cupples, JB Meigs, … - Obesity …, 2003 - predimed.onmedic.net
Roberto Elosua,* Serkalem Demissie,† L. Adrienne Cupples,† James B. Meigs, ‡ Peter WF
Wilson,§ Ernst J. Schaefer,* Dolores Corella,* and Jose M. Ordovas* ... Abstract ELOSUA,
ROBERTO, SERKALEM DEMISSIE, L. ADRIENNE CUPPLES, JAMES B. MEIGS, PETER ...
Cited by 31 - Related articles - View as HTML - BL Direct - All 7 versions


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