- ►diabetesjournals.org SJ Kim, DG Jeong, SK Jeong, TS Yoon, SE … - Diabetes, 2007 - Am Diabetes Assoc Insulinoma-associated protein-2 (IA-2) is a major autoantigen in type 1 diabetes
that occurs through autoimmune-mediated β-cell destruction. We present here the
crystal structure of the protein tyrosine phosphatase (PTP)-like domain of ... Cited by 7 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org G Fenalti, CS Hampe, Y Arafat, RHP Law, JP … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—The COOH-terminal region on GAD65 was the major autoantigenic site.
B-cell epitopes were distributed within two separate clusters around different
faces of the COOH-terminal domain. Inclusion of epitope sites in the ... Cited by 8 - Related articles - BL Direct - All 3 versions
T Shibasaki, S Seino - Methods in enzymology, 2005 - ncbi.nlm.nih.gov Rab, monomeric small Ras-like GTPase, regulates intracellular membrane
trafficking in eukaryotic cells. Rab3 is involved in the exocytotic process in a
variety of secretory cells including neuronal, neuroendocrine, endocrine, ... Cited by 3 - Related articles - BL Direct - All 2 versions
R Ananieva-Jordanova, M Evans, T Nakamatsu, … - Journal of Autoimmunity, 2005 - Elsevier A hybridoma secreting a human monoclonal autoantibody to the islet cell
autoantigen IA-2 was prepared from peripheral lymphocytes of a patient with type
1 diabetes and Graves' disease using EBV infection followed by fusion with ... Cited by 4 - Related articles - All 3 versions
- ►nih.gov [PDF] PG Drake, GH Peters, HS Andersen, W … - Biochemical Journal, 2003 - pubmedcentral.nih.gov Islet-cell antigen 512 (IA-2) and phogrin (IA-2β) are atypical members of the
receptor protein tyrosine phosphatase (PTP) family that are characterized by a
lack of activity against conven- tional PTP substrates. The physiological ... Cited by 11 - Related articles - BL Direct - All 9 versions
G Fenalti, CS Hampe, KO'Connor, JP Banga, … - Molecular Immunology, 2007 - Elsevier Autoantibodies to the 65 kDa isoform of glutamate decarboxylase (GAD65) are
associated with type I diabetes and recognise highly conformational epitope(s)
that remain to be defined. The human recombinant Fab from mAb b96.11 ... Cited by 5 - Related articles - All 2 versions
- ►endojournals.org CS Hampe, R Nalini, MR Maldonado, TR Hall, … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Context: We previously characterized patients presenting with diabetic
ketoacidosis prospectively into four subgroups of ketosis-prone diabetes
mellitus (KPDM), based on the presence or absence of ß-cell autoimmunity ... Cited by 6 - Related articles - BL Direct - All 4 versions
ME Primo, EA Anton, AL Villanueva, E … - Clinical Immunology, 2003 - Elsevier Of the two homologous forms of glutamic acid decarboxylase, GAD65 and GAD67,
only GAD65 is a common target of autoimmunity. Epitope profiles of
autoantibodies to GAD65 (GADA) in 140 type 1 diabetes, adult-onset diabetes ... Cited by 7 - Related articles - All 4 versions
JCW PhD, AMB PhD, MJR PhD - Am Diabetes Assoc Gustavo Fenalti (BSc (Pharm)1, Christiane S. Hampe (PhD)2, Yasir Arafat (BSc
(Eng)1, Ruby HP Law (PhD)1, J. Paul Banga (PhD)3, Ian R. Mackay (MD)1, James C.
Whisstock (PhD)1 ,, Ashley M. Buckle (PhD)1, Merrill J. Rowley (PhD)1 Related articles
O Raha, S Chowdhury, S Dasgupta, P … - International Journal of Diabetes in Developing …, 2009 - ijddc.com Type 1 diabetes is a multifactorial disease with an early age of onset, in which
the insulin producing β cell of the pancreas are destroyed because of
autoimmunity. It is the second most common chronic disease in children and ... Related articles - Cached - All 2 versions
