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Scholar Results 1 - 10 of about 101 related to Sarkar: Induction of Indoleamine 2, 3-Dioxygenase by Interferon-γ in Human Islets. (0.09 sec) 

Induction of Indoleamine 2, 3-Dioxygenase by Interferon-γ in Human Islets

- shouxi.net
SA Sarkar, R Wong, SI Hackl, O Moua, RG … - Diabetes, 2007 - Am Diabetes Assoc
Indoleamine 2,3-dioxygenase (IDO) catalyzes the initial, rate-limiting step of
tryptophan (Trp) catabolism along the kynurenine (KYN) pathway, and its
induction in cells of the immune system in response to cytokines has been ...
Cited by 6 - Related articles - BL Direct - All 5 versions

SOCS3 drives proteasomal degradation of indoleamine 2, 3-dioxygenase (IDO) and …

- pnas.org
C Orabona, MT Pallotta, C Volpi, F Fallarino, … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences
Despite their common ability to activate intracellular signaling through
CD80/CD86 molecules, cytotoxic T lymphocyte antigen 4 (CTLA-4)-Ig and CD28-Ig
bias the downstream response in opposite directions, the latter promoting ...
Cited by 4 - Related articles - All 7 versions

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone


F Fallarino, G Luca, M Calvitti, F Mancuso, C … - Journal of Experimental Medicine, 2009 - jem.rupress.org
Type I diabetes mellitus is caused by autoimmune destruction of pancreatic β
cells, and effective treatment of the disease might require rescuing β cell
function in a context of reinstalled immune tolerance. Sertoli cells (SCs) ...
Related articles - All 3 versions

IDO Mediates TLR9-Driven Protection from Experimental Autoimmune Diabetes


F Fallarino, C Volpi, T Zelante, C Vacca, M … - The Journal of Immunology, 2009 - Am Assoc Immnol
Originally predicated on the recognition of an increasing prevalence of allergy,
the hygiene hypothesis was later found to accom- modate the contrasting
epidemiologic trends in developed countries for infectious vs autoimmune ...
Related articles - All 3 versions

MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in …

- nih.gov
TK Berthoud, SJ Dunachie, S Todryk, AVS Hill … - Journal of Immunological Methods, 2009 - Elsevier
For many years the IFN-γ ex vivo ELISPOT has been a major assay for assessing
human T-cell responses generated by malaria vaccines. The ELISPOT assay is a
sensitive assay, but an imperfect correlate of protection against malaria. ...
Related articles - All 4 versions

Cutting Edge: Autocrine TGF-{beta} Sustains Default Tolerogenesis by IDO-Competent …

- jimmunol.org
ML Belladonna, C Volpi, R Bianchi, C Vacca, C … - The Journal of Immunology, 2008 - Am Assoc Immnol
CD8 – and CD8 + dendritic cells (DCs) are distinct subsets of mouse splenic
accessory cells with opposite but flexible programs of Ag presentation, leading
to immunogenic and tolerogenic responses, respectively. In this study, we ...
Cited by 7 - Related articles - All 3 versions

Mouse pancreatic islets are resistant to indoleamine 2, 3 dioxygenase-induced general …

- amjpathol.org
… F Forouzandeh, A Moeenrezakhanlou, GR Rayat … - American Journal of Pathology, 2009 - ASIP
Islet transplantation is a promising treatment for diabetes. However, it faces
several challenges including requirement of systemic immunosuppression.
Indoleamine 2,3-dioxygenase (IDO), a tryptophan degrading enzyme, is a ...
Cited by 1 - Related articles - All 7 versions

Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B …


SA Sarkar, B Kutlu, K Velmurugan, S Kizaka- … - Diabetologia, 2009 - Springer
Page 1. ARTICLE Cytokine-mediated induction of anti-apoptotic genes that
are linked to nuclear factor kappa-B (NF-κB) signalling ...
Cited by 2 - Related articles - All 2 versions

Sertoli cell line lacks the immunoprotective properties associated with primary Sertoli cells


JM Dufour, B Dass, KR Halley, GS Korbutt, DE … - Cell Transplantation, 2008 - ingentaconnect.com
Sertoli cells are important for maintenance of the immune privileged environment
of the testis and prolong survival of cotransplanted cells. The objective of the
current study was to examine the immunoprotective properties of a mouse ...
Cited by 1 - Related articles - All 2 versions

Persistence of Residual Beta Cells and Islet Autoimmunity during Increasing Duration of …


S Reddy, CCH Cheung, RCC Chai, JA … - System, 1927 - interscience.wiley.com
The precise fate of beta cells and the presence of islet infiltrates after onset
of type 1 diabetes have not yet been fully characterized. Recently we showed
that in newly diabetic NOD mice an appreciable number of beta cells remain. ...
Cited by 1 - Related articles - All 4 versions


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