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Scholar Results 1 - 10 of about 101 related to Yermen: Pro-survival role of gelsolin in mouse β-cells. (0.12 sec) 

Pro-survival role of gelsolin in mouse β-cells

- shouxi.net
B Yermen, A Tomas, PA Halban - Diabetes, 2007 - Am Diabetes Assoc
We have previously shown that the Ca 2+ -dependent actin-severing protein
gelsolin plays an important role in regulated insulin secretion. The aim of this
study was to determine the role of gelsolin in β-cell survival as it has ...
Cited by 6 - Related articles - BL Direct - All 6 versions

Rab GTPase-Activating Protein AS160 Is a Major Downstream Effector of Protein Kinase B/Akt …


K Bouzakri, P Ribaux, A Tomas, G Parnaud, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE— Protein kinase B/Akt plays a central role in β-cells, but little
is known regarding downstream Akt substrates in these cells. Recently, Rab
GTPase-activating protein AS160, a substrate of Akt, was shown to be ...
Cited by 5 - Related articles - BL Direct - All 4 versions

Obestatin conformational features: A strategy to unveil obestatin's biological role?


M Scrima, P Campiglia, C Esposito, I Gomez- … - Biochemical and Biophysical Research …, 2007 - Elsevier
Obestatin and its derivative Ob(11–23) are recently discovered peptides
produced in the rat stomach. They have proven to be involved in the regulation
of energy balance, inhibiting feeding, causing reductions in food intake, ...
Cited by 4 - Related articles - All 3 versions

Inhibitory role of Src family tyrosine kinases on Ca2+-dependent insulin release

- physiology.org
H Cheng, SG Straub, GWG Sharp - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Both neurotransmitter release and insulin secretion occur via regulated
exocytosis and share a variety of similar regulatory mechanisms. It has been
suggested that Src family tyrosine kinases inhibit neurotransmitter release ...
Cited by 5 - Related articles - BL Direct - All 5 versions

Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta-cells from TNF-alpha …


K Bouzakri, P Ribaux, PA Halban - Journal of Biological Chemistry, 2009 - ASBMB
Obesity and type 2 diabetes present partially overlapping phenotypes with
systemic inflammation as a common feature, raising the hypothesis that elevated
cytokine levels may contribute to peripheral insulin resistance as well as ...
Related articles - All 3 versions

Silencing Mitogen-activated Protein 4 Kinase 4 (MAP4K4) Protects Beta Cells from Tumor …


K Bouzakri, P Ribaux, PA Halban - Journal of Biological Chemistry, 2009 - ASBMB
Obesity and type 2 diabetes present partially overlapping phenotypes with
systemic inflammation as a common feature, raising the hypothesis that elevated
cytokine levels may contribute to peripheral insulin resistance as well as ...
Related articles - All 2 versions

Induction of CXCL1 by Extracellular Matrix and Autocrine Enhancement by Interleukin-1 in …

- endojournals.org
P Ribaux, JA Ehses, N Lin-Marq, F … - Endocrinology, 2007 - Endocrine Soc
As we showed previously, the extracellular matrix (ECM) derived from rat bladder
carcinoma cells (804G-ECM) has positive effects on rat primary β-cell function
and survival in vitro. The aim of this study was to define β-cell genes ...
Cited by 12 - Related articles - BL Direct - All 4 versions

The role of inflammation in insulitis and β-cell loss in type 1 diabetes


DL Eizirik, ML Colli, F Ortis - Nature Reviews Endocrinology, 2009 - phx1.medscape.com
Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease with a strong
inflammatory component. The latest studies indicate that innate immunity and
inflammatory mediators have a much broader role in T1DM than initially ...
Cited by 7 - Related articles - All 8 versions

Unlike ghrelin, obestatin does not exert any relevant activity in chondrocytes


R Lago, R Gomez, C Dieguez, JJ Gomez-Reino … - British Medical Journal, 2007 - ard.bmj.com
Correspondence to: Dr ME Hettema, Division of Rheumatology and Clinical
Immunology, University Medical Center Groningen, PO Box 30001, 9700 RB
Groningen, the Netherlands; mehettema@int.umcg.nl ... REFERENCES 1 Merkel ...
Cited by 7 - Related articles - BL Direct - All 2 versions

Glucose effects on beta-cell growth and survival require activation of insulin receptors and …


A Assmann, K Ueki, JN Winnay, RN Kulkarni - Molecular and Cellular Biology, 2009 - Am Soc Microbiol
Page 1. " " 1 " " 1 " 2 " Glucose effects on beta-cell growth and survival require
activation of insulin 3 " receptors and insulin receptor substrate-2 4 " 5 " ...
Cited by 1 - Related articles - All 3 versions


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