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FGFR3 is a negative regulator of the expansion of pancreatic epithelial cells


S Arnaud-Dabernat, M Kritzik, AG Kayali, YQ … - Diabetes, 2007 - Am Diabetes Assoc
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are key signaling
molecules for pancreas development. Although FGFR3 is a crucial developmental
gene, acting as a negative regulator of bone formation, its participation ...
Cited by 9 - Related articles - BL Direct - All 4 versions

FGFR3 Is a Negative Regulator of the Expansion of Pancreatic Epithelial Cells


SADM Kritzik, AG Kayali, YQ Zhang, G Liu, C … - 糖尿病学杂志, 2007 - journal.shouxi.net
【摘要】 Fibroblast growth factors (FGFs) and their receptors (FGFRs) are
key signaling molecules for pancreas development. Although FGFR3 is a crucial
developmental gene, acting as a negative regulator of bone formation, its ...
Related articles - Cached

FGFR1-IIIb is a putative marker of pancreatic progenitor cells


C Cras-Méneur, R Scharfmann - Mechanisms of development, 2002 - Elsevier
The pancreas develops from buds that derive from the endodermal epithelium of
the digestive tract. The progenitor cells that will give rise to the mature
pancreatic cells reside within this epithelium. However, their exact ...
Cited by 8 - Related articles - All 3 versions

Tyrosine kinase receptors are crucial for normal-cell development and function


S Arnaud-Dabernat, N Sarvetnick - Expert Review of Endocrinology and Metabolism, 2007 - ingentaconnect.com
Signaling pathways play critical roles in most physiological and pathological
processes and convert an extracellular stimulus into a change of function in the
recipient cell. Intracellular messages originate from the activation of ...
Related articles - All 3 versions

Acanthosis Nigricans and Insulin Sensitivity in patients with Achondroplasia and …


KS Alatzoglou, PC Hindmarsh, C Brain, J … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
Methods and Results: We compared the results of a 1.75 g/kg oral glucose
tolerance test performed in patients with ACH/HCH and AN with age-, sex-, and
puberty-matched short children. Three of the patients were treated with ...
Related articles - All 3 versions

β-Cell Replication by Loosening the Brakes of Glucagon-Like Peptide-1 Receptor Signaling


FC Schuit, DJ Drucker - Diabetes, 2008 - Am Diabetes Assoc
A decrease in β-cell mass is a well-known key pathogenic event in diabetes, not
only in human subjects with type 1 patients, where β-cells are destroyed by the
immune system, but also in type 2 diabetes where reduced β-cell function ...
Related articles - BL Direct - All 4 versions

Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with …


WM Abdel-Rahman, J Kalinina, S Shoman, S … - Human Mutation - interscience.wiley.com
We previously described striking molecular features including high frequency of
membranous -catenin in subsets of familial colon cancers with as yet unknown
predisposition. We hypothesized that such tumors might carry mutations in ...
Related articles

Expression of Id1 in adult, regenerating and developing pancreas


H Hua, N Sarvetnick - Endocrine, 2007 - Springer
Abstract Several key transcription factors are necessary for alpha cell
development in the pancreas. In this study, we describe the expression of
Inhibition of DNA-binding protein 1 (Id1) in the developing as well as the ...
Related articles - BL Direct - All 3 versions

FGFR3 contributes to intestinal crypt cell growth arrest


S Arnaud-Dabernat, D Yadav, N Sarvetnick - Journal of Cellular Physiology, 2008 - interscience.wiley.com
Fibroblast growth factors (FGFs) are important regulators of the dynamic
development and turnover of tissues. Among FGF receptors, FGFR3 expression is
confined in the intestinal crypts. We examined FGFR3-deficient mice and saw ...
Cited by 1 - Related articles - BL Direct - All 3 versions

COUP-TFI Coordinates Cortical Patterning, Neurogenesis, and Laminar Fate and …

- oxfordjournals.org
A Faedo, GS Tomassy, Y Ruan, H Teichmann, S … - Cerebral Cortex, 2008 - Oxford Univ Press
A major unsolved question in cortical development is how proliferation,
neurogenesis, regional growth, regional identity, and laminar fate specification
are coordinated. Here we provide evidence, using loss-of-function and ...
Cited by 13 - Related articles - All 4 versions


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