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Scholar Results 1 - 10 of about 101 related to Serino: Mice Heterozygous for Tumor Necrosis Factor-α Converting Enzyme Are Protected From.... (0.10 sec) 

Mice Heterozygous for Tumor Necrosis Factor-α Converting Enzyme Are Protected …


M Serino, R Menghini, L Fiorentino, R Amoruso, A … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—Tumor necrosis factor (TNF)-α is known to affect insulin sensitivity, glucose, and
lipid metabolism through alternative and redundant mechanisms at both translational and
post-translational levels. TNF-α exerts its paracrine effects once the membrane-anchored ...
Cited by 19 - Related articles - BL Direct - All 4 versions

TNF-α converting enzyme heterozygous mice are protected from obesity-induced …


M Serino, R Menghini, L Fiorentino, R Amoruso, A … - Diabetes, 2007 - Am Diabetes Assoc
1Laboratory of Molecular Medicine, Department of Internal Medicine, 2Department of
Biopathology, University of Rome “Tor Vergata”, Rome, Italy; ... *Address correspondence
to: Massimo Federici, MD Department of Internal Medicine University of Rome-“Tor ...
Cited by 1 - Related articles

Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and …


R Menghini, S Menini, R Amoruso, L Fiorentino, V … - Gastroenterology, 2009 - Elsevier
Obesity-driven, low-grade inflammation affects systemic metabolic function and can lead to insulin
resistance, hepatic steatosis, and atherosclerosis. Decreased expression of tissue inhibitor of
metalloproteinase 3 (Timp3) is a catalyst for insulin resistance and inflammation. Timp3 is ...
Cited by 4 - Related articles - All 3 versions

Deficiency of TNF {alpha} Converting Enzyme (TACE/ADAM17) Causes a Lean, …


RW Gelling, W Yan, S Al-Noori, A Pardini, GJ Morton, K … - Endocrinology, 2008 - Endocrine Soc
Energy homeostasis involves central nervous system integration of afferent inputs that coordinately
regulate food intake and energy expenditure. Here, we report that adult homozygous TNF converting
enzyme (TACE)-deficient mice exhibit one of the most dramatic examples of ...
Cited by 2 - Related articles - All 4 versions

Timp3 deficiency in insulin receptor–haploinsufficient mice promotes diabetes and …

- nih.gov
M Federici, ML Hribal, R Menghini, H … - Journal of Clinical …, 2005 - Am Soc Clin Investig
1 Center for Atherosclerosis, “Policlinico Tor Vergata” University Hospital, Rome, Italy. 2 Department
of Internal Medicine, University of Rome “Tor Vergata,” Rome, Italy. 3 Department of
Medicine, College of Physicians and Surgeons of Columbia University, New York, New ...
Cited by 38 - Related articles - BL Direct - All 9 versions

Genetic polymorphisms of tumor necrosis factor-{alpha} modify the association …

- ajcn.org
B Fontaine-Bisson, T Wolever, JL Chiasson, R … - American Journal of …, 2007 - Am Soc Nutrition
2 Supported by a grant from the Canada Institutes of Health Research (CIHR- MCT-44205) and
the Advanced Foods and Materials Network. BF-B is a recipient of a Natural Sciences and Engineering
Research Council of Canada Postgraduate Scholarship. AE-S holds a Canada Research ...
Cited by 3 - Related articles - BL Direct - All 7 versions

Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine …


Y Wu, JP Ouyang, K Wu, SS Wang, CY … - British journal of …, 2005 - pubmedcentral.nih.gov
Protein tyrosine phosphatase 1B (PTP1B) acts as a physiological negative regulator of insulin
signaling by dephosphorylating the activated insulin receptor (IR). Here we examine the role
of PTP1B in the insulin-sensitizing action of rosiglitazone (RSG) in skeletal muscle and liver.
Cited by 13 - Related articles - BL Direct - All 4 versions

Improved glucose homeostasis in mice with muscle-specific deletion of protein- …

- nih.gov
M Delibegovic, KK Bence, N Mody, EG Hong, … - Molecular and cellular …, 2007 - Am Soc Microbiol
Obesity and type 2 diabetes are characterized by insulin resistance. Mice lacking the
protein-tyrosine phosphatase PTP1B in all tissues are hypersensitive to insulin but also have
diminished fat stores. Because adiposity affects insulin sensitivity, the extent to which ...
Cited by 15 - Related articles - BL Direct - All 11 versions

Roles of plasma interleukin-6 and tumor necrosis factor-α and FFA and TG in the …


K Jiao, H Liu, J Chen, D Tian, J Hou, AD Kaye - Cytokine, 2008 - Elsevier
The role of adipokines in development of insulin resistance still remains controversial. The purpose
of the present study was to examine the dynamic changes of fasting plasma levels of
interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), free fatty acids (FFA) and insulin in a ...
Cited by 5 - Related articles - All 3 versions

Ceramide mediates TNF-α-induced insulin resistance on GLUT4 gene expression …


S Fernández-Veledo, R Hernandez, T … - … of physiology and …, 2006 - informahealthcare.com
Tumour necrosis factor (TNF)-α impaired insulin induction on GLUT4 mRNA in foetal brown
adipocytes, as demonstrated by quantitative RT-PCR and Northern blot. We have explored the
hypothesis that some effects of TNF-α could be mediated by the generation of ceramide, ...
Cited by 16 - Related articles - BL Direct - All 7 versions


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