- ►diabetesjournals.org I Jarchum, JC Baker, T Yamada, T Takaki, MP … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—We found that HLA-A*0201-restricted T-cells isolated from the islets
of the transgenic mice were specific for Ins1 L3–11, Ins1 B5–14, and Ins1/2
A2–10. Insulin-reactive T-cells were present in the islets of mice as ... Cited by 10 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org P Blancou, R Mallone, E Martinuzzi, S Severe … - The Journal of Immunology, 2007 - Am Assoc Immnol Type 1 diabetes (T1D) results from the autoimmune destruction of pancreatic
cells. CD8 + T cells have recently been assigned a major role in cell injury.
Consequently, the identification of autoreactive CD8 + T cells in humans ... Cited by 10 - Related articles - All 6 versions
- ►jimmunol.org T Takaki, MP Marron, CE Mathews, ST … - The Journal of Immunology, 2006 - Am Assoc Immnol In both humans and NOD mice, particular MHC genes are primary contributors to
development of the autoreactive CD4 + and CD8 + T cell responses against
pancreatic cells that cause type 1 diabetes (T1D). Association studies have ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org E Enee, E Martinuzzi, P Blancou, JM Bach, R … - The Journal of Immunology, 2008 - Am Assoc Immnol CD8 + T cells play an important role in the initiation of insulitis and in the
destructive stage leading to insulin-dependent diabetes mellitus. A string of
recent studies has led to the identification of numerous HLA-A2-restricted ... Cited by 2 - Related articles - All 3 versions
U Fuchs, HH von Dorsche, M Ziegler, H … - Zeitschrift für mikroskopisch-anatomische Forschung, 1988 - ncbi.nlm.nih.gov 1: Z Mikrosk Anat Forsch. 1988;102(5):829-32. Anti-glucagon insulitis
and A-cell hyperplasia of pancreatic islets. Fuchs U, von ... Cited by 2 - Related articles - All 2 versions
A Gergely, L Korányl, T Halmos, M Zsombok, F … - Annales immunologiae Hungaricae, 1973 - ncbi.nlm.nih.gov 1: Ann Immunol Hung. 1973;17:231-3. Anti-glucagon antibodies in diabetes
mellitus. Gergely A, Korányl L, Halmos T, Zsombók M, Péterfy ... Cited by 3 - Related articles
- ►diabetesjournals.org R Mallone, E Martinuzzi, P Blancou, G Novelli … - Diabetes, 2007 - Am Diabetes Assoc Despite the understanding that type 1 diabetes pathogenesis is mediated by
T-cells, detection of these rare lymphocytes remains largely elusive. Suitable
T-cell assays are highly needed, since they could offer preclinical ... Cited by 31 - Related articles - BL Direct - All 6 versions
[CITATION] Molecular complementarity III. Molecular complementarity as the basis for peptide hormone …
- ►oxfordjournals.org Y Tikochinski, D Elias, C Steeg, H Marcus, M … - International immunology, 1999 - Jpn Soc Immunol T cells involved in autoimmune diseases have been characterized by the genetic
elements used to construct their autoimmune TCR. In the present study, we
sequenced the and ß chains of the TCR expressed by a CD4 + T cell clone, ... Cited by 4 - Related articles - BL Direct - All 8 versions
- ►jimmunol.org CP Wong, L Li, JA Frelinger, R Tisch - The Journal of Immunology, 2006 - Am Assoc Immnol Type 1 diabetes (T1D) 3 is an organ-specific autoimmune disease characterized by
the destruction of the insulin-producing pancreatic cells. The nonobese diabetic
(NOD) mouse spontaneously develops T cell-dependent cell destruction (1, 2, ... Cited by 18 - Related articles - BL Direct - All 4 versions