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Scholar Results 1 - 10 of about 101 related to Obrosova: High-Fat Diet–Induced Neuropathy of Pre-Diabetes and Obesity. (0.11 sec) 

High-Fat Diet–Induced Neuropathy of Pre-Diabetes and Obesity

- shouxi.net
IG Obrosova, O Ilnytska, VV Lyzogubov, IA … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—HFD-fed mice developed obesity, increased plasma FFA and insulin
concentrations, and impaired glucose tolerance. They also had motor and sensory
nerve conduction deficits, tactile allodynia, and thermal hypoalgesia in ...
Cited by 20 - Related articles - BL Direct - All 6 versions

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin- …


VR Drel, P Pacher, I Vareniuk, I Pavlov, O … - European journal of pharmacology, 2007 - pubmedcentral.nih.gov
Whereas an important role of free radicals and oxidants in peripheral diabetic
neuropathy is well established, the contribution of nitrosative stress and, in
particular, of the highly reactive oxidant peroxynitrite, has not been ...
Cited by 13 - Related articles - All 6 versions

Poly (ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory …

- nih.gov
O Ilnytska, VV Lyzogubov, MJ Stevens, VR … - Diabetes, 2006 - Am Diabetes Assoc
Poly(ADP-ribose) polymerase (PARP) activation is emerging as a fundamental
mechanism in the pathogenesis of diabetes complications including diabetic
neuropathy. This study evaluated the role of PARP in diabetic sensory ...
Cited by 26 - Related articles - BL Direct - All 10 versions

Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice

- academia.edu [PDF] 
I Vareniuk, IA Pavlov, VR Drel, VV Lyzogubov, … - Experimental Neurology, 2007 - Elsevier
Nitrosative stress contributes to nerve conduction slowing, thermal hypoalgesia,
and impaired nitrergic innervation in animal models of Type 1 diabetes. The role
for reactive nitrogen species in Type 2 diabetes-associated neuropathy ...
Cited by 19 - Related articles - All 5 versions

The Leptin-Deficient (ob/ob) Mouse

- diabetesjournals.org
VR Drel, N Mashtalir, O Ilnytska, J Shin, F Li … - Diabetes, 2006 - Am Diabetes Assoc
Whereas functional, metabolic, neurotrophic, and morphological abnormalities of
peripheral diabetic neuropathy (PDN) have been extensively explored in
streptozotocin-induced diabetic rats and mice (models of type 1 diabetes), ...
Cited by 31 - Related articles - BL Direct - All 7 versions

Evaluation of the peroxynitrite decomposition catalyst Fe (III) tetra-mesitylporphyrin …


VR Drel, P Pacher, I Vareniuk, IA Pavlov, O … - International journal of molecular medicine, 2007 - pubmedcentral.nih.gov
Whereas the important role of free radicals in diabetes-associated complications
is well established, the contributions of the highly reactive oxidant
peroxynitrite have not been properly explored. The present study used a ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin- …

- physiology.org
IG Obrosova, VR Drel, CL Oltman, N Mashtalir … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Evidence for important roles of the highly reactive oxidant peroxynitrite in
diabetic complications is emerging. We evaluated the role of peroxynitrite in
early peripheral neuropathy and vascular dysfunction in STZ-diabetic rats. ...
Cited by 16 - Related articles - BL Direct - All 5 versions

Inducible nitric oxide synthase gene deficiency counteracts multiple manifestations of …

- pbrc.edu [PDF] 
I Vareniuk, IA Pavlov, IG Obrosova - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Evidence for the importance of peroxyni- trite, a
product of superoxide anion radical reaction with nitric oxide, in peripheral
diabetic neuropathy is emerging. The role of specific nitric oxide synthase ...
Cited by 4 - Related articles - All 5 versions

Protective effects of cyclooxygenase-2 gene inactivation against peripheral nerve …


AP Kellogg, TD Wiggin, DD Larkin, JM Hayes, … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—Under normal conditions, there were no differences in blood glucose,
peripheral nerve electrophysiology, markers of oxidative stress, inflammation,
and IENF density between COX-2 +/+ and COX-2 −/− mice. After 6 months, ...
Cited by 14 - Related articles - BL Direct - All 4 versions

Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats

- aspetjournals.org
MJ Stevens, F Li, VR Drel, OI Abatan, H Kim, … - Journal of Pharmacology and Experimental …, 2007 - ASPET
In diabetes, activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP)
is an important effector of oxidative-nitrosative injury, which contributes to
the development of experimental diabetic peripheral neuropathy (DPN). ...
Cited by 21 - Related articles - All 7 versions


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