- ►diabetesjournals.org K Sachidanandam, V Portik-Dobos, AK Harris, JR … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Vascular remodeling, characterized by extracellular matrix deposition and increased
media-to-lumen (M/l) ratio, contributes to the development of microvascular complications in
diabetes. Matrix metalloproteinases (MMPs) play an important role in the regulation of ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►physiology.org … , MM Elgebaly, AK Harris, JR Hutchinson, … - American Journal of …, 2008 - Am Physiological Soc Vascular dysfunction, which presents either as an increased response to vasoconstrictors or
an impaired relaxation to dilator agents, results in worsened cardiovascular outcomes in
diabetes. We have established that the mesenteric circulation in Type 2 diabetes is ... Cited by 4 - Related articles - All 3 versions
- ►physiology.org AK Harris, MM Elgebaly, W Li, K … - American Journal of …, 2008 - Am Physiological Soc Diabetes increases the risk of stroke and contributes to poor clinical outcomes in this patient
population. Myogenic tone of the cerebral vasculature, including basilar arteries, plays a key
role in controlling cerebral blood flow. Increased myogenic tone is ameliorated with ET ... Cited by 7 - Related articles - BL Direct - All 4 versions
MM Elgebaly, V Portik-Dobos, K Sachidanandam, D … - Vascular pharmacology, 2007 - Elsevier Endothelin (ET-1) is chronically elevated in diabetes. However, role of ET-1 in increased oxidative
stress in type 2 diabetes is less clear. This study tested the hypotheses that: 1) oxidative stress
markers are increased and total antioxidant capacity is decreased in diabetes, and 2) ... Cited by 6 - Related articles - All 3 versions
- ►ebmonline.org K Sachidanandam, A Harris, J Hutchinson, A Ergul - Experimental Biology and …, 2006 - SEBM Vascular dysfunction characterized by a hyperreactivity to vasoconstrictors and/or impaired vascular
relaxation contributes to increased incidence of cardiovascular disease in diabetes. Endothelin
(ET)-1, a potent vasoconstrictor, is chronically elevated in diabetes. However, the role of ... Cited by 11 - Related articles - BL Direct - All 3 versions
AK Harris, JR Hutchinson, K Sachidanandam, MH … - Diabetes, 2005 - Am Diabetes Assoc The risk of cerebrovascular disease is four- to sixfold higher in patients with diabetes. Vascular
remodeling, characterized by extracellular matrix deposition and an increased media-to-lumen
ratio, occurs in diabetes and contributes to the development of complications. However, ... Cited by 29 - Related articles - BL Direct - All 5 versions
MM Elgebaly, A Kelly, AK Harris, H Elewa, V … - Canadian Journal of …, 2008 - ingentaconnect.com Abstract: Insulin resistance involves decreased phosphorylation of insulin receptor substrate
(IRS) proteins and (or) Akt. In the vasculature, modulated Akt phosphorylation may cause impaired
vasorelaxation via decreased eNOS activation. Diet-induced insulin resistance enhances ... Cited by 5 - Related articles - All 6 versions
J Su, DI Palen, PA Lucchesi, K Matrougui - Biochemical and Biophysical …, 2006 - Elsevier The measurement of blood pressure in vivo was similar in KO and WT mice. Pressure-induced
myogenic tone, contractions to angiotensin-II and phenylephrine were similar in both
groups. The inhibition of MMP2/9 ((2R)-2-[(4-biphenylylsulfonyl) ... Cited by 5 - Related articles - All 4 versions
ET Brøndum, H Nilsson, C Aalkjær - Horm Metab Res, 2005 - thieme-connect.com Several different rat models have been developed for both type 1 and type 2 diabetes with the
aim of displaying specific traits of diabetes. For example, a review on nephropathy associated
with type 2 diabetes included 16 different rodent models [1]; new models are still being ... Cited by 15 - Related articles - All 4 versions
K Kitada, N Yui, C Matsumoto, T Mori, M Ohkita, Y … - Journal of Pharmacology …, 2009 - ASPET Page 1. JPET #157065 1 Inhibition of Endothelin ETB Receptor System Aggravates Neointimal
Hyperplasia after Balloon Injury of Rat Carotid Artery Kento Kitada, Nozomi Yui, Chika
Matsumoto, Tatsuhiko Mori, Mamoru Ohkita, and Yasuo Matsumura ... Related articles - All 2 versions
