Z Lu, YP Jiang, XH Xu, LM Ballou, IS Cohen, RZ Lin - Diabetes, 2007 - Am Diabetes Assoc RESULTS—Diabetic mice had a cardiac contractility defect, reduced PI 3-kinase signaling in
the heart, and decreased l-type Ca 2+ current (I Ca,L ) density in myocytes compared with control
nondiabetic littermates. The lower I Ca,L density in myocytes from diabetic mice is due at ... Cited by 3 - Related articles - BL Direct - All 3 versions
I Findlay, S Suzuki, S Murakami, Y Kurachi - Progress in Biophysics and …, 2008 - Elsevier The inactivation of the L-type Ca 2+ current is composed of voltage-dependent and calcium-dependent
mechanisms. The relative contribution of these processes is still under dispute and the idea that
the voltage-dependent inactivation could be subject to further modulation by other ... Cited by 2 - Related articles - All 3 versions
YG Wang, X Ji, M Pabbidi, AM Samarel, SL … - The Journal of …, 2009 - Physiological Soc We previously reported that short-term (2 h) plating of cat atrial myocytes on the extracellular
matrix protein, laminin (LMN) decreases adenylate cyclase activity and β 1 -adrenergic receptor
(β 1 -AR) stimulation of L-type Ca 2+ current (I Ca,L ). The present study sought to ... Cited by 2 - Related articles - All 5 versions
V Yarotskyy, G Gao, BZ Peterson, KS … - The Journal of …, 2009 - Physiological Soc Timothy syndrome (TS) is a multiorgan dysfunction caused by a Gly to Arg substitution at position
406 (G406R) of the human CaV1.2 (L-type) channel. The TS phenotype includes severe arrhythmias
that are thought to be triggered by impaired open-state voltage-dependent inactivation ( ... Cited by 2 - Related articles - All 6 versions
M Yamada, K Ohta, A Niwa, N Tsujino, T Nakada, M … - Journal of Membrane …, 2008 - Springer Page 1. Contribution of L-Type Ca 2+ Channels to Early Afterdepolarizations Induced by I Kr
and I Ks Channel Suppression in Guinea Pig Ventricular Myocytes Mitsuhiko Yamada Æ Keisuke
Ohta Æ Atsunori Niwa Æ Natsuko Tsujino Æ Tsutomu Nakada Æ Masamichi Hirose ... Cited by 2 - Related articles - All 6 versions
R Treinys, J Jurevicius - Medicina (Kaunas, Lithuania), 2008 - medicina.kmu.lt Summary. This review analyzes the structure and regulation mechanisms of voltage- dependent
L-type Ca2+ channel in the heart. L-type Ca2+ channels in the heart are com- posed of four different
polypeptide subunits, and the pore-forming subunit a1 is the most important part of the ... Cited by 2 - Related articles - View as HTML - All 3 versions
- ►physiology.org X Chen, X Zhang, DM Harris, V Piacentino … - American Journal of …, 2008 - Am Physiological Soc Abnormal L-type Ca 2+ channel (LTCC, also named Cav1.2) density and regulation are important
contributors to depressed contractility in failing hearts. The LTCC agonist BAY K 8644 (BAY
K) has reduced inotropic effects on failing myocardium. We hypothesized that BAY K ... Cited by 3 - Related articles - BL Direct - All 3 versions
GA Fuller-Bicer, G Varadi, SE Koch, M … - American Journal of …, 2009 - Am Physiological Soc Cardiac L-type voltage-dependent Ca 2+ channels are heteromultimeric polypeptide complexes
of 1 -, 2 / -, and β-subunits. The 2 / -1-subunit possesses a stereoselective, high-affinity binding
site for gabapentin, widely used to treat epilepsy and postherpetic neuralgic pain as well ... Cited by 3 - Related articles - All 3 versions
- ►jbc.org J Ohrtman, B Ritter, A Polster, KG Beam, S … - Journal of Biological …, 2008 - ASBMB The proximal C terminus of the cardiac L-type calcium channel (Ca V 1.2) contains structural
elements important for the binding of calmodulin (CaM) and calcium-dependent inactivation,
and exhibits extensive sequence conservation with the corresponding region of the ... Cited by 3 - Related articles - All 9 versions
