M García-Fernández, P Ortega-Sáenz, A … - Diabetes, 2007 - Am Diabetes Assoc The counterregulatory response to hypoglycemia is essential for life and
particularly important for insulin-treated diabetic subjects; however, the
underlying mechanisms remain largely unknown (1–3). The existence of low ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►nih.gov SV Conde, A Obeso, C Gonzalez - The Journal of Physiology, 2007 - Physiological Soc Glucose deprivation (hypoglycaemia) is counterbalanced by a neuroendocrine
response in order to induce fast delivery of glucose to blood. Some central
neurons can sense glucose, but nevertheless the most important glucose ... Cited by 4 - Related articles - BL Direct - All 6 versions
- ►nih.gov M Zhang, J Buttigieg, CA Nurse - The Journal of Physiology, 2007 - Physiological Soc The mammalian carotid body (CB) is a polymodal chemosensor which can detect low
blood glucose (hypoglycaemia), leading to increased afferent discharge and
activation of counter-regulatory autonomic pathways. The underlying ... Cited by 15 - Related articles - BL Direct - All 8 versions
MGP Ortega-Sáenz, A Castellano, J López- … - DIABETES, 2007 - Am Diabetes Assoc T he counterregulatory response to hypoglycemia is essential for life and
particularly important for insulin-treated diabetic subjects; however, the
underlying mechanisms remain largely unknown (1–3). The existence of low ... Related articles
- ►physoc.org DS Ward, WA Voter, S Karan - The Journal of Physiology, 2007 - Physiological Soc Animal and tissue studies have indicated that the carotid bodies are sensitive
to glucose concentrations within the physiological range. This glucose
sensitivity may modulate the ventilatory response to hypoxia, with ... Cited by 4 - Related articles - BL Direct - All 8 versions
P Kumar - The Journal of Physiology, 2007 - Physiological Soc The paper by Zhang et al. (2007) in this issue of The Journal of Physiology
suggests that the mammalian carotid body may, in addition to sensing hypoxia,
function as a peripheral glucosensor. The carotid body might therefore join ... Cited by 5 - Related articles - BL Direct - All 9 versions
P Ortega-Sáenz, A Pascual, JI Piruat, J … - Respiratory physiology & neurobiology, 2007 - Elsevier We have studied carotid body (CB) glomus cell sensitivity to changes in O 2
tension in three different genetically engineered animals models using thin CB
slices and monitoring the secretory response to hypoxia by amperometry. ... Cited by 6 - Related articles - All 3 versions
- ►ersj.org.uk J Lopez-Barneo, P Ortega-Saenz, R Pardal, A … - European Respiratory Journal, 2008 - ersj.org.uk The carotid body (CB) is a neural crest-derived organ whose major function is to
sense changes in arterial oxygen tension to elicit hyperventilation in hypoxia.
The CB is composed of clusters of neuron-like glomus, or type-I, cells ... Cited by 8 - Related articles - All 6 versions
R Pardal, J López-Barneo - Nature neuroscience, 2002 - nature.com Decreased plasma glucose concentration elicits a complex neuroendocrine response
that prevents or rapidly corrects hypoglycemia as required to preserve brain
function 1, 2, 3, 4 ; however, where and how low glucose is sensed is ... Cited by 75 - Related articles - BL Direct - All 4 versions
P Ortega-Saenz, A Pascual, R Gomez-Diaz, J … - Journal of General Physiology, 2006 - jgp.rupress.org Hemeoxygenase-2 (HO-2) is an antioxidant enzyme that can modulate recombinant
maxi-K + channels and has been proposed to be the acute O 2 sensor in the
carotid body (CB). We have tested the physiological contribution of this ... Cited by 25 - Related articles - BL Direct - All 7 versions
