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Scholar Results 1 - 10 of about 101 related to Lynn: MicroRNA expression is required for pancreatic islet cell genesis in the mouse. (0.12 sec) 

MicroRNA expression is required for pancreatic islet cell genesis in the mouse

- diabetesjournals.org
FC Lynn, P Skewes-Cox, Y Kosaka, MT … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—Sequencing of small RNAs identified over 125 miRNAs, including 18
novel sequences, with distinct expression domains within the developing
pancreas. To test the developmental contribution of these miRNAs, we ...
Cited by 29 - Related articles - BL Direct - All 4 versions

Quantitative differential expression analysis reveals miR-7 as major islet microRNA

- diabetesresearch.org [PDF] 
V Bravo-Egana, S Rosero, RD Molano, A … - Biochemical and Biophysical Research …, 2008 - Elsevier
MicroRNAs (miRNAs) are non-coding gene products that regulate gene expression
through specific binding to target mRNAs. Cell-specific patterns of miRNAs are
associated with the acquisition and maintenance of a given phenotype, such ...
Cited by 11 - Related articles - All 4 versions

MicroRNA Expression is Required for Pancreatic Islet Cell Genesis in the Mouse


FCL PhD, P Skewes-Cox, YK PhD, MS … - Am Diabetes Assoc
MicroRNA Expression is Required for Pancreatic Islet Cell Genesis in the Mouse
... 1 Francis C. Lynn PhD, 1 Peter Skewes-Cox BA, 1 Yasuhiro Kosaka PhD, ...
1,2 Michael T. McManus PhD, 4 Brian D. Harfe PhD and 1,3, Michael S. German MD.
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Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in …


WP Kloosterman, AK Lagendijk, RF Ketting, … - PLoS Biol, 2007 - biology.plosjournals.org
Several vertebrate microRNAs (miRNAs) have been implicated in cellular processes
such as muscle differentiation, synapse function, and insulin secretion. In
addition, analysis of Dicer null mutants has shown that miRNAs play a role ...
Cited by 63 - Related articles - Cached - All 8 versions

Regulation of the expression of components of the exocytotic machinery of insulin-secreting …


P Lovis, S Gattesco, R Regazzi - Biological Chemistry, 2008 - reference-global.com
Fine-tuning of insulin secretion from pancreatic b-cells participates in blood
glucose homeostasis. Defects in this process can lead to chronic hyperglycemia
and dia- betes mellitus. Several proteins controlling insulin exo- cytosis ...
Cited by 13 - Related articles - BL Direct - All 3 versions

MicroRNA-124a Regulates Foxa2 Expression and Intracellular Signaling in Pancreatic {beta …

- jbc.org
N Baroukh, MA Ravier, MK Loder, EV Hill, A … - Journal of Biological Chemistry, 2007 - ASBMB
MicroRNAs (miRNAs) are short non-coding RNAs that have been implicated in
fine-tuning gene regulation, although the precise roles of many are still
unknown. Pancreatic development is characterized by the complex sequential ...
Cited by 52 - Related articles - All 7 versions

MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult …


M Correa-Medina, V Bravo-Egana, S Rosero, C … - Gene Expression Patterns, 2009 - Elsevier
MicroRNAs (miRNA) are small non-coding RNAs that inhibit gene expression through
binding to complementary messenger RNA sequences. miRNAs have been predicted to
target genes important for pancreas development, proper endocrine cell ...
Cited by 6 - Related articles - All 2 versions

MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of …

- jbc.org
V Plaisance, A Abderrahmani, V Perret- … - Journal of Biological Chemistry, 2006 - ASBMB
Insulin release from pancreatic -cells plays an essential role in blood glucose
homeostasis. Several proteins controlling insulin exocytosis have been
identified, but the factors determining the expression of the components of ...
Cited by 55 - Related articles - BL Direct - All 6 versions

New pancreas from old: microregulators of pancreas regeneration

- cell.com
MV Joglekar, VS Parekh, AA Hardikar - Trends in Endocrinology & Metabolism, 2007 - Elsevier
MicroRNAs (miRNAs) are 18–22 nucleotide RNA molecules that mediate
post-transcriptional gene silencing, primarily by binding to the 3′
untranslated region of their target mRNA. Several studies have demonstrated ...
Cited by 5 - Related articles - All 4 versions

Expression of islet-specific microRNAs during human pancreatic development


MV Joglekar, VM Joglekar, AA Hardikar - Gene Expression Patterns, 2009 - Elsevier
During pancreatic islet development, sequential changes in gene expression are
known to be necessary for efficient differentiation and function of the
endocrine pancreas. Several studies till now have demonstrated that ...
Cited by 7 - Related articles - All 2 versions


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