- ►diabetesjournals.org [PDF] N Grarup, CS Rose, EA Andersson, G Andersen, AL … - Diabetes, 2007 - Am Diabetes Assoc Page 1. Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2
Genes With Type 2 Diabetes and Impaired Insulin Release in 10,705 Danish Subjects
Validation and Extension of Genome-Wide Association Studies ... Cited by 60 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org L Pascoe, A Tura, SK Patel, IM Ibrahim, E Ferrannini, E … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE— Type 2 diabetes is characterized by impaired pancreatic β-cell function and decreased
insulin sensitivity. Genome-wide association studies have identified common, novel type 2 diabetes
susceptibility loci within the FTO, CDKAL1, CDKN2A/CDKN2B, IGF2BP2, HHEX/IDE, and ... Cited by 58 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org H Staiger, A Stančáková, J Zilinskaite, M Vänttinen, T … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—SNPs rs1111875 and rs7923837 were not associated with anthropometric data
(age, weight, height, BMI, body fat, and waist and hip circumference). After adjustment for
center, family relationship, sex, age, and BMI, both SNPs were also not associated with ... Cited by 17 - Related articles - BL Direct - All 4 versions
H Staiger, F Machicao, N Stefan, O Tschritter, C … - PLoS One, 2007 - pubmedcentral.nih.gov Background. Type 2 diabetes arises when insulin resistance-induced compensatory insulin secretion
exhausts. Insulin resistance and/or b-cell dysfunction result from the interaction of environmental
factors (high-caloric diet and reduced physical activity) with a predisposing polygenic ... Cited by 47 - Related articles - All 5 versions
N Grarup, CS Rose, EA Andersson, G Andersen, AL … - DIABETES, 2007 - Am Diabetes Assoc Page 1. Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2
Genes With Type 2 Diabetes and Impaired Insulin Release in 10,705 Danish Subjects
Validation and Extension of Genome-Wide Association Studies ... Related articles
- ►diabetesjournals.org [PDF] ND Palmer, MO Goodarzi, CD Langefeld, J Ziegler, JM … - Diabetes, 2008 - Am Diabetes Assoc Nicholette D. Palmer, 1,2 Mark O. Goodarzi, 3 Carl D. Langefeld, 4 Julie Ziegler, 4 Jill M.
Norris, 5 ... Steven M. Haffner, 6 Michael Bryer-Ash, 7,8 Richard N. Bergman, 9 Lynne E.
Wagenknecht, 4 ... Kent D. Taylor, 3 Jerome I. Rotter, 3 and Donald W. Bowden 1,2,10 Cited by 26 - Related articles - BL Direct - All 4 versions
N Grarup, G Andersen, NT Krarup, A Albrechtsen, O … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Homozygous carriers of the minor diabetes risk G-allele of the CDC123/CAMK1D
rs12779790 showed an 18% decrease in insulinogenic index (95% CI 10–27%; P = 4 × 10
−5 ), an 18% decrease in corrected insulin response (CIR) (8.1–29%; P = 4 × 10 −4 ), and ... Cited by 16 - Related articles - All 6 versions
- ►diabetesjournals.org [PDF] S Omori, Y Tanaka, A Takahashi, H Hirose, A … - Diabetes, 2007 - Am Diabetes Assoc Page 1. Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX , SLC30A8 and KCNJ11
with susceptibility to type 2 diabetes in a Japanese population Shintaro Omori MD 1,2 ,
Yasushi Tanaka MD, Ph.D. 2 , Atsushi Takahashi Ph.D. 3 , Hiroshi ... Cited by 53 - Related articles - BL Direct - All 4 versions
H Lango, CNA Palmer, AD Morris, E Zeggini, AT … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVES—Genome-wide association studies have dramatically increased the number of
common genetic variants that are robustly associated with type 2 diabetes. A possible clinical
use of this information is to identify individuals at high risk of developing the disease, so ... Cited by 28 - Related articles - All 5 versions
M Horikoshi, K Hara, C Ito, N Shojima, R Nagai, K Ueki, … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Recently, several groups have carried out whole-genome association
studies in European and European- origin populations and found novel type 2 diabetes- susceptibility
genes, fat mass and obesity associated (FTO), solute carrier family 30 (zinc transporter), ... Cited by 50 - Related articles - BL Direct - All 2 versions
