P Pissios, U Ozcan, E Kokkotou, T Okada, CW Liew, S … - Diabetes, 2007 - Am Diabetes Assoc Melanin concentrating hormone (MCH) is a hypothalamic neuropeptide known to play a critical
role in energy balance. We have previously reported that overexpression of MCH is associated
with mild obesity. In addition, mice have substantial hyperinsulinemia and islet ... Cited by 14 - Related articles - BL Direct - All 6 versions
E Kokkotou, AC Moss, D Torres, I … - Proceedings of the …, 2008 - National Acad Sciences Melanin-concentrating hormone (MCH) is expressed primarily in the hypothalamus and has
a positive impact on feeding behavior and energy balance. Although MCH is expressed in the
gastrointestinal tract, its role in this system remains elusive. We demonstrate that, ... Cited by 9 - Related articles - All 5 versions
B Coumans, T Grisar, JL Nahon, B Lakaye - Regulatory Peptides, 2007 - Elsevier The mRNA encoding prepro-Melanin concentrating hormone (ppMCH) is mainly expressed in
the central nervous system but has also been detected at lower amount in many peripheral tissues
including spleen and thymus. At the peptide level however, several forms of the precursor ... Cited by 3 - Related articles - All 3 versions
H Sandig, J McDonald, J Gilmour, M Arno … - Proceedings of the …, 2007 - National Acad Sciences Th1 and Th2 cells represent the two main functional subsets of CD4 + T helper cell, and are defined
by their cytokine expression. Human Th1 cells express IFNγ, whilst Th2 cells express IL-4,
IL-5, and IL-13. Th1 and Th2 cells have distinct immunological functions, and can drive ... Cited by 5 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org JY Jeon, RL Bradley, EG Kokkotou, FE Marino, X Wang … - Diabetes, 2006 - Am Diabetes Assoc Ablation of the hypothalamic peptide, melanin-concentrating hormone (MCH), leads to a lean
phenotype and resistance to diet-induced obesity. Observation of MCH −/− mice at older ages
suggested that these effects persist in mice >1 year old. Leanness secondary to caloric ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►physiology.org RL Bradley, JPR Mansfield, E Maratos- … - American Journal of …, 2002 - Am Physiological Soc Energy homeostasis is regulated by peripheral signals, such as leptin, and by several orexigenic
and anorectic neuropeptides. Recently, we reported that the orexigenic neuropeptide
melanin-concentrating hormone (MCH) stimulates leptin production by rat adipocytes and ... Cited by 35 - Related articles - BL Direct - All 2 versions
- ►nursing2009.com E Kokkotou, DO Espinoza, D Torres, I … - British Medical …, 2009 - gut.bmj.com Methods: In human intestinal xenografts grown in mice, changes in the expression of MCH and
its receptors following treatment with Clostridium difficile toxin A, the causative agent of
antibiotic-associated diarrhoea in hospitalised patients, were examined. In colonocytes, ... Cited by 2 - Related articles - All 4 versions
DR Luthin - Life Sci, 2007 - 万方数据资源系统 Over the past ten years, tremendous advances in our understanding of the role of the hypothalamic
neurohormone, melanin-concentrating hormone (MCH), and its involvement in the regulation
of food intake and body weight have been achieved. The MCHR1 receptor has been ... Cited by 20 - Related articles - All 8 versions
M Verlaet, A Adamantidis, B Coumans, G Chanas, W … - FEBS letters, 2002 - Elsevier Melanin-concentrating hormone (MCH) is highly expressed in the brain and modulates feeding
behavior. It is also expressed in some peripheral tissues where its role remains unknown. We
have investigated MCH function in human and mouse immune cells. RT-PCR analysis ... Cited by 20 - Related articles - All 8 versions
MA Bednarek - Current Topics in Medicinal Chemistry, 2007 - ingentaconnect.com Abstract: The melanin-concentrating hormone receptor 1 (MCH-1R) has been recognized as
a receptor which mediates effects of the endogenous melanin-concentrating hormone
(MCH) on appetite and body weight gain in rodents. In the last several years, a number of ... Cited by 3 - Related articles - BL Direct - All 3 versions
