- ►diabetesjournals.org L Zheng, SJ Howell, DA Hatala, K Huang, TS … - Diabetes, 2007 - Am Diabetes Assoc It has been previously reported that aspirin inhibited the development of
diabetic retinopathy in diabetic animals, raising the possibility that
anti-inflammatory drugs may have beneficial effects on diabetic ... Cited by 42 - Related articles - BL Direct - All 12 versions
- ►diabetesjournals.org TS Kern, CM Miller, Y Du, L Zheng, S Mohr, … - Diabetes, 2007 - Am Diabetes Assoc Pharmacologic treatment of diabetic retinopathy via eyedrops could have
advantages but has not been successful to date. We explored the effect of
topical Nepafenac, an anti-inflammatory drug known to reach the retina when ... Cited by 35 - Related articles - BL Direct - All 4 versions
SID Rats, N Extract, EMS Assay, TF Array, T … - canadiancpd.medscape.com Nuclear proteins from retinas were isolated as described by others [34] with
some modifications. All steps were carried out on ice or at 4°C. Freshly
isolated retinas were rinsed in PBS buffer and spun at 1,500g for 5 min. ... Related articles
- ►shouxi.net W Sun, C Gerhardinger, Z Dagher, T Hoehn, … - Diabetes, 2005 - Am Diabetes Assoc The prevention of diabetic retinopathy requires drugs that leverage the benefits
of glycemic control without adding the burden of side effects. Aspirin at
dosages of 1–1.5 g/day has prevented manifestations of diabetic retinal ... Cited by 24 - Related articles - BL Direct - All 6 versions
L Zheng, Y Du, C Miller, RA Gubitosi-Klug, TS … - Diabetologia, 2007 - Springer Page 1. ARTICLE Critical role of inducible nitric oxide synthase in degeneration
of retinal capillaries in mice with streptozotocin-induced diabetes ... Cited by 29 - Related articles - BL Direct - All 7 versions
- ►physiology.org Y Du, VP Sarthy, TS Kern - … Journal of Physiology- Regulatory, Integrative and …, 2004 - Am Physiological Soc A nonselective inhibitor of cyclooxygenase (COX; high-dose aspirin) and a
relatively selective inhibitor of inducible nitric oxide synthase (iNOS;
aminoguanidine) have been found to inhibit development of diabetic ... Cited by 57 - Related articles - BL Direct - All 4 versions
- ►iovs.org L Zheng, B Gong, DA Hatala, TS Kern - Investigative ophthalmology & visual science, 2007 - ARVO METHODS. I/R injury to the retinas was induced in Lewis rats and C57BL/6J mice
by elevating intraocular pressure (IOP), and reperfusion was established
immediately afterward. Some rats were pretreated with aminoguanidine (AMG, ... Cited by 21 - Related articles - BL Direct - All 3 versions
TS Kern, RL Engerman - Diabetes, 2001 - Am Diabetes Assoc Effects of aminoguanidine and aspirin on the development of retinopathy have
been examined in 5-year studies of diabetic dogs. Either agent was administered
daily in doses of 20–25 mg · kg −1 · day −1 . Because severity of ... Cited by 164 - Related articles - BL Direct - All 5 versions
- ►shouxi.net JK Krady, A Basu, CM Allen, Y Xu, KF … - Diabetes, 2005 - Am Diabetes Assoc Diabetes leads to vascular leakage, glial dysfunction, and neuronal apoptosis
within the retina. The goal of the studies reported here was to determine the
role that retinal microglial cells play in diabetic retinopathy and assess ... Cited by 81 - Related articles - All 10 versions
L Zheng, C Szabó, TS Kern - Diabetes, 2004 - Am Diabetes Assoc The current study investigated the role of poly(ADP-ribose) polymerase (PARP) in
the development of diabetic retinopathy. Activity of PARP was increased in whole
retina and in endothelial cells and pericytes of diabetic rats. ... Cited by 98 - Related articles - BL Direct - All 5 versions
