LM Russo, E del Re, D Brown, HY Lin - Diabetes, 2007 - Am Diabetes Assoc Transforming growth factor-β (TGF-β) has previously been implicated in the progression of diabetic
nephropathy, including the onset of fibrosis and albuminuria. Here we report for the first time
the use of a high-affinity TGF-β1 binding molecule, the soluble human TGF-β type II ... Cited by 24 - Related articles - BL Direct - All 6 versions
LM Russo, E del Re, D Brown, HY Lin - DIABETES, 2007 - Am Diabetes Assoc Transforming growth factor- (TGF- ) has previously been implicated in the progression of diabetic
nephropathy, including the onset of fibrosis and albuminuria. Here we report for the first time
the use of a high-affinity TGF- 1 binding molecule, the soluble human TGF- type II recep- ... Related articles
- ►bentham.org [PDF] LM Hilliard, LM Russo, WD Comper - Current Hypertension …, 2007 - ingentaconnect.com Abstract: Albuminuria is the increased excretion of the serum protein albumin into the urine. Albuminuria
is classically seen as an important diagnostic marker of declining kidney function, however, more
recently albuminuria has also been implicated as a marker for cardiovascular and ... Cited by 4 - Related articles - BL Direct - All 4 versions
LM Russo, TM Osicka, GC Brammar, R … - American journal of …, 2000 - content.karger.com Background/Aims: Recent studies show that albuminuria may be the result of changes in
post-glomerular cellular uptake and processing of albumin. This study aims to determine whether
this processing is disrupted in diabetes and/or hypertension. Methods: Diabetes (d) was ... Cited by 22 - Related articles - BL Direct - All 5 versions
LM Russo, GC Brammar, G Jerums, WD … - Journal of …, 2003 - journals.lww.com Objectives Albumin excretion is modulated post-filtration by lysosomal processing that produces
a spectrum of albumin-derived material in urine, much of which is not detected by conventional
immunoassays. This study aimed to determine the efficacy of ramipril treatment (+ RAM) ... Cited by 15 - Related articles - BL Direct - All 3 versions
SP Clavant, JM Forbes, V Thallas, TM Osicka, G … - Nephron …, 2000 - content.karger.com Angiotensin II (ANG II) is intimately involved in normal renal function, and is estimated to exist
at a normal physiological range of 6-10 nM within the renal tubules. The potential role that intrarenal
ANG II may play in renal disease was assessed by perfusing isolated rat kidneys with or ... Cited by 17 - Related articles - BL Direct - All 5 versions
O Schenk, H Ling, K Sebekova, S … - Mineral and electrolyte …, 2000 - content.karger.com Nephromegaly is a prominent feature of diabetic nephropathy and predominantly reflects increased
renal tubule mass, mostly due to hypertrophy. To elucidate pathogenetic factors involved, we
studied the effects of high glucose (HG) alone, and in combination with hormones/growth ... Cited by 18 - Related articles - All 6 versions
LM Hilliard, TM Osicka, SP Clavant, PJ Robinson, … - The Journal of laboratory …, 2006 - Elsevier This study examines the existence of the urinary albumin degradation pathway and the proposed
role of receptor-mediated endocytosis in this process using the isolated perfused rat kidney
(IPK) model. Albumin-derived peptides in IPK urine are analyzed in terms of their relative ... Cited by 17 - Related articles - All 6 versions
S Chen, DJ Wassenhove-McCarthy, Y Yamaguchi, LB … - Kidney International, 2008 - nature.com Podocytes synthesize the majority of the glomerular basement membrane components with some
contribution from the glomerular capillary endothelial cells. The anionic charge of heparan sulfate
proteoglycans is conferred by covalently attached heparan sulfate glycosaminoglycans ... Cited by 8 - Related articles - All 5 versions
J van den Born, B Pisa, MAH Bakker, JWAM Celie, … - Journal of Biological …, 2006 - ASBMB Heparan sulfate (HS) proteoglycans are major anionic glycoconjugates of the glomerular basement
membrane and are thought to contribute to the permeability properties of the glomerular capillary
wall. In this study we evaluated whether the development of (micro) albuminuria in early ... Cited by 19 - Related articles - All 6 versions