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Scholar Results 1 - 10 of about 101 related to Russo: Evidence for a Role of Transforming Growth Factor (TGF)-β1 in the Induction of Postglomer.... (0.11 sec) 

Evidence for a Role of Transforming Growth Factor (TGF)-β1 in the Induction of …


LM Russo, E del Re, D Brown, HY Lin - Diabetes, 2007 - Am Diabetes Assoc
Transforming growth factor-β (TGF-β) has previously been implicated in the progression of diabetic
nephropathy, including the onset of fibrosis and albuminuria. Here we report for the first time
the use of a high-affinity TGF-β1 binding molecule, the soluble human TGF-β type II ...
Cited by 24 - Related articles - BL Direct - All 6 versions

[PDF] Amelioration by Soluble TGF-Type II Receptor


LM Russo, E del Re, D Brown, HY Lin - DIABETES, 2007 - Am Diabetes Assoc
Transforming growth factor- (TGF- ) has previously been implicated in the progression of diabetic
nephropathy, including the onset of fibrosis and albuminuria. Here we report for the first time
the use of a high-affinity TGF- 1 binding molecule, the soluble human TGF- type II recep- ...
Related articles

Insights into the relationship between hypertension and albuminuria

- bentham.org [PDF] 
LM Hilliard, LM Russo, WD Comper - Current Hypertension …, 2007 - ingentaconnect.com
Abstract: Albuminuria is the increased excretion of the serum protein albumin into the urine. Albuminuria
is classically seen as an important diagnostic marker of declining kidney function, however, more
recently albuminuria has also been implicated as a marker for cardiovascular and ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Renal processing of albumin in diabetes and hypertension in rats


LM Russo, TM Osicka, GC Brammar, R … - American journal of …, 2000 - content.karger.com
Background/Aims: Recent studies show that albuminuria may be the result of changes in
post-glomerular cellular uptake and processing of albumin. This study aims to determine whether
this processing is disrupted in diabetes and/or hypertension. Methods: Diabetes (d) was ...
Cited by 22 - Related articles - BL Direct - All 5 versions

The effect of ramipril on albumin excretion in diabetes and hypertension: the role of …


LM Russo, GC Brammar, G Jerums, WD … - Journal of …, 2003 - journals.lww.com
Objectives Albumin excretion is modulated post-filtration by lysosomal processing that produces
a spectrum of albumin-derived material in urine, much of which is not detected by conventional
immunoassays. This study aimed to determine the efficacy of ramipril treatment (+ RAM) ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Reversible angiotensin II-mediated albuminuria in rat kidneys is dynamically …


SP Clavant, JM Forbes, V Thallas, TM Osicka, G … - Nephron …, 2000 - content.karger.com
Angiotensin II (ANG II) is intimately involved in normal renal function, and is estimated to exist
at a normal physiological range of 6-10 nM within the renal tubules. The potential role that intrarenal
ANG II may play in renal disease was assessed by perfusing isolated rat kidneys with or ...
Cited by 17 - Related articles - BL Direct - All 5 versions

High-glucose media enhance the responsiveness of tubular cells to growth …


O Schenk, H Ling, K Sebekova, S … - Mineral and electrolyte …, 2000 - content.karger.com
Nephromegaly is a prominent feature of diabetic nephropathy and predominantly reflects increased
renal tubule mass, mostly due to hypertrophy. To elucidate pathogenetic factors involved, we
studied the effects of high glucose (HG) alone, and in combination with hormones/growth ...
Cited by 18 - Related articles - All 6 versions

Characterization of the urinary albumin degradation pathway in the isolated …


LM Hilliard, TM Osicka, SP Clavant, PJ Robinson, … - The Journal of laboratory …, 2006 - Elsevier
This study examines the existence of the urinary albumin degradation pathway and the proposed
role of receptor-mediated endocytosis in this process using the isolated perfused rat kidney
(IPK) model. Albumin-derived peptides in IPK urine are analyzed in terms of their relative ...
Cited by 17 - Related articles - All 6 versions

Loss of heparan sulfate glycosaminoglycan assembly in podocytes does not lead …


S Chen, DJ Wassenhove-McCarthy, Y Yamaguchi, LB … - Kidney International, 2008 - nature.com
Podocytes synthesize the majority of the glomerular basement membrane components with some
contribution from the glomerular capillary endothelial cells. The anionic charge of heparan sulfate
proteoglycans is conferred by covalently attached heparan sulfate glycosaminoglycans ...
Cited by 8 - Related articles - All 5 versions

No change in glomerular heparan sulfate structure in early human and …


J van den Born, B Pisa, MAH Bakker, JWAM Celie, … - Journal of Biological …, 2006 - ASBMB
Heparan sulfate (HS) proteoglycans are major anionic glycoconjugates of the glomerular basement
membrane and are thought to contribute to the permeability properties of the glomerular capillary
wall. In this study we evaluated whether the development of (micro) albuminuria in early ...
Cited by 19 - Related articles - All 6 versions


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