DM Lehman, KJ Hunt, RJ Leach, J Hamlington, R Arya, … - Diabetes, 2007 - Am Diabetes Assoc TCF7L2 acts as both a repressor and transactivator of genes, as directed by the Wnt signaling
pathway. Recently, several highly correlated sequence variants located within a haplotype block
of the TCF7L2 gene were observed to associate with type 2 diabetes in three Caucasian ... Cited by 49 - Related articles - BL Direct - All 4 versions
M Horikoshi, K Hara, C Ito, R Nagai, P Froguel, T … - Diabetologia, 2007 - Springer Page 1. SHORT COMMUNICATION A genetic variation of the transcription factor 7-like
2 gene is associated with risk of type 2 diabetes in the Japanese population M. Horikoshi
& K. Hara & C. Ito & R. Nagai & P. Froguel & T. Kadowaki ... Cited by 59 - Related articles - BL Direct - All 4 versions
T Hayashi, Y Iwamoto, K Kaku, H Hirose, S Maeda - Diabetologia, 2007 - Springer Abstract Aims/hypothesis The transcription factor 7-like 2 gene (TCF7L2) has been shown to
be strongly associated with an increased risk of type 2 diabetes in white populations. To further
investigate the involvement of TCF7L2 in confer- ring susceptibility to type 2 diabetes, we ... Cited by 46 - Related articles - BL Direct - All 3 versions
- ►ccmb.res.in [PDF] GR Chandak, CS Janipalli, S Bhaskar, SR Kulkarni, P … - Diabetologia, 2007 - Springer Abstract Aims and hypothesis India has the greatest number of diabetic subjects in any one
country, but the genetic basis of type 2 diabetes mellitus in India is poorly understood. Common
non-coding variants in the transcription factor 7-like 2gene (TCF7L2) have recently been ... Cited by 85 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org LJ Scott, LL Bonnycastle, CJ Willer, AG Sprau, AU … - Diabetes, 2006 - Am Diabetes Assoc Transcription factor 7-like 2 (TCF7L2) is part of the Wnt signaling pathway. Genetic variants within
TCF7L2 on chromosome 10q were recently reported to be associated with type 2 diabetes in
Icelandic, Danish, and American (US) samples. We previously observed a modest ... Cited by 139 - Related articles - BL Direct - All 9 versions
C Marzi, C Huth, M Kolz, H Grallert, C … - … and metabolic research …, 2007 - ncbi.nlm.nih.gov Recently, significant associations between common variants of the transcription factor 7-like
2 gene ( TCF7L2) and type 2 diabetes have been reported. This study was designed to replicate
the reported associations of the two highly correlated (r (2)=0.86) TCF7L2 single ... Cited by 31 - Related articles - BL Direct - All 3 versions
- ►pubget.com [PDF] SE Humphries, D Gable, JA Cooper, H Ireland, JW … - Journal of Molecular …, 2006 - Springer Page 1. ORIGINAL ARTICLE Common variants in the TCF7L2 gene and predisposition
to type 2 diabetes in UK European Whites, Indian Asians and Afro-Caribbean men and
women Steve E. Humphries & David Gable & Jackie A. Cooper & ... Cited by 88 - Related articles - BL Direct - All 8 versions
- ►nih.gov Y Guo, D Xiong, H Shen, L Zhao, P Xiao, Y Guo, W … - British Medical …, 2006 - jmg.bmj.com Results: Single markers (12 tagging SNPs and 4 untaggable SNPs) and haplotypes (5
blocks) were tested for associations, using family-based designs. SNP4 (rs4988300) and SNP6
(rs634008) located in block 2 (intron 1) showed significant associations with obesity and ... Cited by 21 - Related articles - BL Direct - All 7 versions
- ►rug.nl [PDF] JV van Vliet-Ostaptchouk, R Shiri-Sverdlov, A … - Diabetologia, 2007 - Springer Page 1. SHORT COMMUNICATION Association of variants of transcription factor 7-like 2 (TCF7L2)
with susceptibility to type 2 diabetes in the Dutch Breda cohort JV van Vliet-Ostaptchouk & R.
Shiri-Sverdlov & A. Zhernakova & E. Strengman & TW van Haeften & ... Cited by 69 - Related articles - BL Direct - All 5 versions
S Mayans, K Lackovic, P Lindgren, K Ruikka, Å … - European Journal of …, 2007 - nature.com A recent study found association of one microsatellite and five single nucleotide polymorphisms
(SNPs) in intron 3 of the TCF7L2 gene with type 2 diabetes (T2D) in the Icelandic, Danish and
American populations. The aim of the present study was to investigate if those SNPs were ... Cited by 33 - Related articles - BL Direct - All 5 versions
