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Scholar Results 1 - 10 of about 101 related to JeBailey: Ceramide-and oxidant-induced insulin resistance involve loss of insulin-dependent.... (0.10 sec) 

Ceramide-and oxidant-induced insulin resistance involve loss of insulin-dependent Rac- …


L JeBailey, O Wanono, W Niu, J Roessler, A … - Diabetes, 2007 - Am Diabetes Assoc
In muscle cells, insulin elicits recruitment of the glucose transporter GLUT4 to
the plasma membrane. This process engages sequential signaling from insulin
receptor substrate (IRS)-1 to phosphatidylinositol (PI) 3-kinase and the ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Ceramide-and Oxidant-Induced Insulin Resistance Involve Loss of Insulin-Dependent Rac- …


LJBO Wanono, W Niu, J Roessler, A Rudich, A … - 糖尿病学杂志, 2007 - journal.shouxi.net
【摘要】 In muscle cells, insulin elicits recruitment of the glucose
transporter GLUT4 to the plasma membrane. This process engages sequential
signaling from insulin receptor substrate (IRS)-1 to phosphatidylinositol ...
Related articles - Cached

GLUT4 vesicle recruitment and fusion are differentially regulated by Rac, AS160, and Rab8A …


VK Randhawa, S Ishikura, I Talior-Volodarsky … - Journal of Biological Chemistry, 2008 - ASBMB
Insulin increases glucose uptake into muscle by enhancing the surface recycling
of GLUT4 transporters. In myoblasts, insulin signals bifurcate downstream of
phosphatidylinositol 3-kinase into separate Akt and Rac/actin arms. ...
Cited by 9 - Related articles - All 4 versions

Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are …


MA Sabin, CE Stewart, EC Crowne, SJ Turner, … - Journal of cellular physiology, 2007 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 15 - Related articles - BL Direct - All 5 versions

Key role for ceramides in mediating insulin resistance in human muscle cells

- shouxi.net
L Pickersgill, GJ Litherland, AS Greenberg, … - Journal of Biological Chemistry, 2007 - ASBMB
Elevated non-esterified fatty acids, triglyceride, diacylglycerol, and ceramide
have all been associated with insulin resistance in muscle. We set out to
investigate the role of intramyocellular lipid metabolites in the induction ...
Cited by 23 - Related articles - All 11 versions

Effects of pioglitazone and high-fat diet on ceramide metabolism in rat skeletal muscles


M Zendzian-Piotrowska, M Baranowski, P … - J Physiol Pharmacol, 2006 - jpp.krakow.pl
Ceramide is involved in the pathogenesis of insulin resistance in skeletal
muscles of humans and rodents. However, there are conflicting reports in the
literature on the effect of thiazolidinediones (a new class of insulin ...
Cited by 7 - Related articles - Cached - All 7 versions

Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in …


DJ Powell, S Turban, A Gray, E Hajduch, HS … - Biochemical Journal, 2004 - pubmedcentral.nih.gov
Non-esterified fatty acids (NEFAs) have been implicated in the pathogenesis of
skeletal muscle insulin resistance that may develop, in part, as a consequence
of a direct inhibitory effect on early insulin signalling events. Here we ...
Cited by 58 - Related articles - BL Direct - All 6 versions

Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes

- nih.gov
D Williams, JE Pessin - Journal of Cell Biology, 2008 - jcb.rupress.org
The functional trafficking steps used by soluble NSF attachment protein receptor
(SNARE) proteins have been difficult to establish because of substantial overlap
in subcellular localization and because in vitro SNARE-dependent binding ...
Cited by 19 - Related articles - BL Direct - All 6 versions

The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP- …

- shouxi.net
FSL Thong, PJ Bilan, A Klip - Diabetes, 2007 - Am Diabetes Assoc
Insulin-dependent phosphorylation of Akt target AS160 is required for GLUT4
translocation. Insulin and platelet-derived growth factor (PDGF) (Akt
activators) or activation of conventional/novel (c/n) protein kinase C ...
Cited by 42 - Related articles - BL Direct - All 5 versions

Clathrin-dependent and independent endocytosis of glucose transporter 4 (GLUT4) in …


CN Antonescu, M Díaz, G Femia, JV Planas, A … - Traffic, 2008 - interscience.wiley.com
In myocytes and adipocytes, insulin increases glucose transporter 4 (GLUT4)
exocytosis by promoting GLUT4 vesicle docking/fusion with the membrane. Less is
known about the mechanism and regulation of GLUT4 endocytosis, particularly ...
Cited by 9 - Related articles - All 3 versions


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