- ►diabetesjournals.org MM Mariappan, D Feliers, S Mummidi, GG Choudhury, … - Diabetes, 2007 - Am Diabetes Assoc Laminin is a glycoprotein that contributes to renal extracellular matrix expansion in diabetes.
We investigated regulation of laminin-β1 synthesis in murine renal proximal tubular epithelial
cells by 30 mmol/l glucose (high glucose), 1 nmol/l insulin (high insulin), and their ... Cited by 14 - Related articles - BL Direct - All 6 versions
- ►amjpathol.org K Sataranatarajan, MM Mariappan, MJ Lee, D Feliers … - American Journal of …, 2007 - ASIP High glucose and high insulin, pathogenic factors in type 2 diabetes, induce rapid synthesis
of the matrix protein laminin-β1 in renal proximal tubular epithelial cells by stimulation of initiation
phase of mRNA translation. We investigated if elongation phase of translation also ... Cited by 7 - Related articles - BL Direct - All 7 versions
- ►asnjournals.org … , MM Mariappan, K Sataranatarajan, MJ Lee, … - Journal of the American …, 2006 - Am Soc Nephrol Ambient protein levels are under coordinated control of transcription, mRNA translation, and
degradation. Whereas transcription and degradation mechanisms have been studied in depth
in renal science, the role of mRNA translation, the process by which peptide synthesis ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►physiology.org [PDF] MJ Lee, D Feliers, MM Mariappan, K … - American Journal of …, 2007 - Am Physiological Soc 63 articles, 36 of which you can access free at: This article cites http://ajprenal.physiology.org
/cgi/content/full/292/2/F617#BIBL ... 4 other HighWire hosted articles: This article has been cited
by ... [PDF] [Full Text] [Abstract] , April 1, 2008; 294 (4): F881-F889. Am J Physiol Renal ... Cited by 25 - Related articles - BL Direct - All 10 versions
D Wu, F Peng, B Zhang, AJ Ingram, B Gao, JC … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Glomerular matrix accumulation is a hall- mark of diabetic
nephropathy. Recent data have linked the serine/threonine kinase protein kinase B (Akt) to matrix
modulation. Here, we studied its role in high glucose- induced collagen elaboration by ... Cited by 9 - Related articles - BL Direct - All 4 versions
M Sakaguchi, M Isono, K Isshiki, T Sugimoto, D … - … and biophysical research …, 2006 - Elsevier Early diabetic nephropathy is characterized by renal hypertrophy that is mainly due to proximal
tubular hypertrophy. Mammalian target of rapamycin (mTOR) is a serine/threonine protein
kinase, and its signaling has been reported to regulate protein synthesis and cellular ... Cited by 18 - Related articles - All 6 versions
- ►physiology.org [PDF] SL Habib, DJ Riley, L Mahimainathan, B … - American Journal of …, 2007 - Am Physiological Soc Page 1. Tuberin Regulates the DNA Repair Enzyme OGG1 Samy L. Habib 1 , Daniel J. Riley
1 , Lenin Mahimainathan, Basant Bhandari, Goutam Ghosh Choudhury 1 and Hanna E. Abboud
1 George O'Brien Kidney Research Center, Department of Medicine, University of Texas ... Cited by 4 - Related articles - BL Direct - All 3 versions
- ►physiology.org [PDF] T Samikkannu, JJ Thomas, GJ Bhat, V … - American Journal of …, 2006 - Am Physiological Soc Page 1. Acute Effect of High Glucose on Long-term Cell growth: A Role for Transient Glucose
Increase in Proximal Tubule Cell Injury By Thangavel Samikkannu, Justin J. Thomas, G.
Jayarama Bhat, Vaughan Wittman and Thomas J. Thekkumkara*. ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org N Lloberas, JM Cruzado, M Franquesa, I … - Journal of the American …, 2006 - Am Soc Nephrol Recent data suggest that the phosphatidylinositol 3-kinase (PI3-K)/Akt/mammalian target of rapamycin
(mTOR) pathway is important in diabetic nephropathy. The effect of mTOR blockade by sirolimus
(SRL) in diabetic kidney disease in rats was investigated. Diabetes was induced by ... Cited by 42 - Related articles - BL Direct - All 5 versions
BS Kasinath, MJ Lee, D Feliers, N Sonenberg - Contemporary Diabetes: The … - Springer With the decoding of the human genome, there is an urgent need for greater under- standing
of how proteins are synthesized and how they function. This notion is predicated on the importance
of proteins as ultimate arbiters of cell function. Studies restricted to investigation of ... Cited by 4 - Related articles
