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Scholar Results 1 - 10 of about 101 related to Lehman: P2 Promoter variants of the hepatocyte nuclear factor 4α gene are associated with.... (0.08 sec) 

P2 Promoter variants of the hepatocyte nuclear factor 4α gene are associated with type 2 …

- shouxi.net
DM Lehman, DK Richardson, CP Jenkinson, KJ … - Diabetes, 2007 - Am Diabetes Assoc
Common and rare variants of the hepatocyte nuclear factor 4α (HNF4A) gene have
been associated with type 2 diabetes and related traits in several populations
suggesting the involvement of this transcription factor in diabetes ...
Cited by 12 - Related articles - BL Direct - All 5 versions

Hepatocyte nuclear factor-4α P2 promoter haplotypes are associated with type 2 diabetes …

- diabetesjournals.org
K Hara, M Horikoshi, H Kitazato, C Ito, M … - Diabetes, 2006 - Am Diabetes Assoc
Hepatocyte nuclear factor (HNF)-4α is a transcription factor known as a key
molecule in the development and functions of the β-cells. In a previously
performed genome-wide scan of Japanese type 2 diabetic sibpairs, we ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Polymorphisms in the gene encoding hepatocyte nuclear factor-4&dgr; and susceptibility to …


K Wanic, MT Malecki, PP Wolkow, T Klupa, J … - Diabetes and Metabolism, 2006 - Elsevier
Recently, several association studies of type 2 diabetes mellitus (T2DM) and the
hepatocyte nuclear factor (HNF)-4α gene were reported with conflicting results.
Our aim was to search for association between two polymorphisms of HNF-4α ...
Cited by 11 - Related articles - All 3 versions

Association study on chromosome 20q11. 21-13.13 locus and its contribution to type 2 …

- tokushima-u.ac.jp [PDF] 
T Tanahashi, D Osabe, K Nomura, S Shinohara, … - Human genetics, 2006 - Springer
Abstract Several linkage studies have predicted that human chromosome 20q is
closely related to type 2 diabetes, but there is no clear evidence that certain
variant(s) or gene(s) have strong effects on the disease within this ...
Cited by 15 - Related articles - BL Direct - All 5 versions

Effect of common polymorphisms in the HNF4α promoter on susceptibility to type 2 diabetes …


M Vaxillaire, C Dina, S Lobbens, A Dechaume … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 440–444 DOI 10.1007/s00125-004-1665-3 SHORT
COMMUNICATION M. Vaxillaire . C. Dina . S. Lobbens . A. Dechaume . ...
Cited by 27 - Related articles - All 3 versions

Highly discrepant proportions of female and male Scandinavian and British Isles ancestry …


TD Als, TH Jorgensen, AD Børglum, PA … - European Journal of Human Genetics, 2006 - nature.com
The Faroe Islands in the North Atlantic Ocean are inhabited by a small
population, whose origin is thought to date back to the Viking Age. Historical,
archaeological and linguistic evidence indicates that the present ...
Cited by 5 - Related articles - BL Direct - All 5 versions

Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes

- shouxi.net
AM Bagwell, JL Bento, JC Mychaleckyj, BI … - Diabetes, 2005 - Am Diabetes Assoc
Hepatocyte nuclear factor 4α (HNF4A), the gene for the maturity-onset diabetes
of the young type 1 monogenic form of type 2 diabetes, is within the type 2
diabetes–linked region on chromosome 20q12-q13.1 and, consequently, is a ...
Cited by 32 - Related articles - All 5 versions

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson …

- diabetesjournals.org
I Barroso, J Luan, E Wheeler, P Whittaker, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Single nucleotide polymorphisms (SNPs) in the P2 promoter region of
HNF4A were originally shown to be associated with predisposition for type 2
diabetes in Finnish, Ashkenazi, and, more recently, Scandinavian ...
Cited by 7 - Related articles - All 8 versions

Variants in hepatocyte nuclear factor 4α are modestly associated with type 2 diabetes in …

- diabetesjournals.org
YL Muller, AM Infante, RL Hanson, L Love- … - Diabetes, 2005 - Am Diabetes Assoc
Single nucleotide polymorphisms (SNPs) within the hepatocyte nuclear factor 4α
(HNF4α) gene are associated with type 2 diabetes in Finns and Ashkenazi Jews.
Previous studies in both populations have reported linkage to type 2 ...
Cited by 37 - Related articles - BL Direct - All 6 versions

A Hepatocyte Nuclear Factor-4α Gene (HNF4A) P2 Promoter Haplotype Linked With Late- …


H Ræder, L Bjørkhaug, S Johansson, K … - Diabetes, 2006 - Am Diabetes Assoc
Variants in hepatocyte nuclear factor (HNF)-4α cause maturity-onset diabetes of
the young, type 1 (MODY1) and may also be risk factors for type 2 diabetes. We
sequenced the HNF4A gene of 95 MODY3-negative probands from the Norwegian ...
Cited by 19 - Related articles - BL Direct - All 4 versions


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