- ►diabetesjournals.org W Winckler, MN Weedon, RR Graham, SA McCarroll, S … - Diabetes, 2007 - Am Diabetes Assoc An important question in human genetics is the extent to which genes causing monogenic forms of
disease harbor common variants that may contribute to the more typical form of that disease. We
aimed to comprehensively evaluate ... Cited by 56 - Related articles - BL Direct - All 5 versions
MS Sandhu, MN Weedon, KA Fawcett, J Wasson … - Nature …, 2007 - pubmedcentral.nih.gov I. Barroso, ATH, MAP, NJW and MSS designed this study; MSS did the statistical analysis, supported
by I. Barroso, AD, SLD, KAF, HL, RJN, PDP, RS and MNWMSS wrote the manuscript with I. Barroso, SLD
and KAF; AD conducted the ... Cited by 81 - Related articles - BL Direct - All 11 versions
J Holmkvist, C Cervin, V Lyssenko, W Winckler, D … - Diabetologia, 2006 - Springer Page 1. ARTICLE Common variants in HNF-1 α and risk of type 2 diabetes J. Holmkvist & C.
Cervin & V. Lyssenko & W. Winckler & D. Anevski & C. Cilio & P. Almgren & G. Berglund &
P. Nilsson & T. Tuomi & CM Lindgren & D. Altshuler & L. Groop Received ... Cited by 27 - Related articles - BL Direct - All 4 versions
LL Bonnycastle, CJ Willer, KN Conneely, AU Jackson, … - Diabetes, 2006 - Am Diabetes Assoc Prior reports have suggested that variants in the genes for maturity-onset diabetes of the young
(MODY) may confer susceptibility to type 2 diabetes, but results have been conflicting and coverage
of the MODY genes has been ... Cited by 40 - Related articles - BL Direct - All 10 versions
J Gudmundsson, P Sulem, V Steinthorsdottir, JT … - Nature genetics, 2007 - nature.com We performed a genome-wide association scan to search for sequence variants conferring risk of
prostate cancer using 1,501 Icelandic men with prostate cancer and 11,290 controls. Follow-up
studies involving three additional ... Cited by 188 - Related articles - BL Direct - All 17 versions
- ►diabetesjournals.org W Winckler, NP Burtt, J Holmkvist, C Cervin, PIW de … - Diabetes, 2005 - Am Diabetes Assoc It is currently unclear how often genes that are mutated to cause rare, early-onset monogenic forms
of disease also harbor common variants that contribute to the more typical polygenic form of each
disease. The gene for MODY3 ... Cited by 46 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org J Holmkvist, P Almgren, V Lyssenko, CM Lindgren, KF … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—The polymorphism rs1169288 in HNF-1α strongly predicted future type 2 diabetes (hazard
ratio [HR] 1.2, P = 0.0002). Also, SNPs rs4810424 and rs3212198 in HNF-4α nominally predicted
future type 2 diabetes (HR 1.3 [95% ... Cited by 18 - Related articles - All 3 versions
- ►diabetesjournals.org [PDF] N Grarup, CS Rose, EA Andersson, G Andersen, AL … - Diabetes, 2007 - Am Diabetes Assoc Page 1. Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2 Genes With
Type 2 Diabetes and Impaired Insulin Release in 10,705 Danish Subjects Validation and
Extension of Genome-Wide Association Studies Niels Grarup, 1 Chrisian ... Cited by 60 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org L Pascoe, A Tura, SK Patel, IM Ibrahim, E Ferrannini, E … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE— Type 2 diabetes is characterized by impaired pancreatic β-cell function and decreased
insulin sensitivity. Genome-wide association studies have identified common, novel type 2 diabetes
susceptibility loci within the FTO, ... Cited by 58 - Related articles - BL Direct - All 4 versions
V Lyssenko, P Almgren, D Anevski, M Orho- … - PLoS …, 2005 - medicine.plosjournals.org By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN10 (SNP43 and
44), KCNJ11 (E23K), UCP2 (−866G>A), and IRS1 (G972R) genes were studied for their ability to
predict T2D in 2,293 individuals ... Cited by 63 - Related articles - Cached - BL Direct - All 10 versions
