Y Okamoto, W Ogawa, A Nishizawa, H Inoue, … - Diabetes, 2007 - Am Diabetes Assoc Phosphoinositide-dependent kinase-1 (PDK1) is implicated in the metabolic
effects of insulin as a key mediator of phosphoinositide 3-kinase–dependent
signaling. Here we show that mice with liver-specific PDK1 deficiency ... Cited by 4 - Related articles - BL Direct - All 5 versions
JM Lucocq - Transgenic research, 2007 - Springer Abstract Genetically modified organisms pres- ent the challenge of quantifying
structures and functions in organs, tissues and cells. Morpholog- ical
investigation is greatly facilitated by taking sections in MRI, CAT ... Cited by 1 - Related articles - BL Direct - All 5 versions
[CITATION] Regulation of hepatic glucose metabolism
DK Granner, DK Scott - Joslin's Diabetes Mellitus. 14th ed. Kahn CR, Weir GC, …, 2005 Cited by 2 - Related articles
P Reddy, D Adhikari, W Zheng, S Liang, T … - Human molecular genetics, 2009 - Oxford Univ Press The molecular mechanisms that control reproductive aging and menopausal age in
females are poorly understood. Here, we provide genetic evidence that
3-phosphoinositide-dependent protein kinase-1 (PDK1) signaling in oocytes ... Cited by 3 - Related articles - All 4 versions
CM Tingen, SK Bristol-Gould, SE Kiesewetter, … - Biology of Reproduction, 2009 - Soc Study Reprod More than half of the primordial follicles that are formed by Day 6 of postnatal
life in the mouse will be eliminated from the ovary by the time of puberty.
Apoptosis, a form of programmed cell death, is one mechanism by which these ... Cited by 4 - Related articles - All 3 versions
[CITATION] Oriente, F
P Puigserver, J Rhee, J Donovan, CJ Walkey … - Kitamura, Y., Altomonte, J., Dong, H., Accili, D. et al, 2003 Cited by 3 - Related articles
- ►physiology.org F Artunc, R Rexhepaj, H Volkl, F Grahammer, … - … Journal of Physiology- Regulatory, Integrative and …, 2006 - Am Physiological Soc The phosphoinositide-dependent kinase-1 (PDK-1) activates the serum- and
glucocorticoid-inducible kinase and protein kinase B isoforms, which, in turn,
are known to stimulate the renal and intestinal Na + -dependent glucose ... Cited by 4 - Related articles - All 3 versions
A Mora, C Lipina, F Tronche, C Sutherland, … - Biochemical Journal, 2005 - pubmedcentral.nih.gov The liver plays an important role in insulin-regulated glucose homoeostasis. To
study the function of the PDK1 (3-phosphoinositide-dependent protein kinase-1)
signalling pathway in mediating insulin's actions in the liver, we employed ... Cited by 32 - Related articles - All 10 versions
J Wu, YD Tseng, CF Xu, TA Neubert, MF … - Nature Structural & Molecular Biology, 2008 - nature.com Insulin receptor substrates 1 and 2 (IRS1 and -2) are crucial adaptor proteins
in mediating the metabolic and mitogenic effects of insulin and insulin-like
growth factor 1. These proteins consist of a pleckstrin homology domain, a ... Cited by 5 - Related articles - BL Direct - All 4 versions
