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Visceral fat adipokine secretion is associated with systemic inflammation in obese humans

- diabetesjournals.org
L Fontana, JC Eagon, ME Trujillo, PE Scherer, … - Diabetes, 2007 - Am Diabetes Assoc
Although excess visceral fat is associated with noninfectious inflammation, it
is not clear whether visceral fat is simply associated with or actually causes
metabolic disease in humans. To evaluate the hypothesis that visceral fat ...
Cited by 108 - Related articles - BL Direct - All 6 versions

Increased infiltration of macrophages in omental adipose tissue is associated with marked …

- shouxi.net
R Cancello, J Tordjman, C Poitou, G Guilhem, … - Diabetes, 2006 - Am Diabetes Assoc
In human obesity, white adipose tissue (WAT) is enriched in macrophages. How
macrophage infiltration in WAT contributes to the complications of obesity is
unknown. This study tested the hypothesis that recruitment of macrophages ...
Cited by 108 - Related articles - BL Direct - All 5 versions

Remodeling phenotype of human subcutaneous adipose tissue macrophages

- ahajournals.org
V Bourlier, A Zakaroff-Girard, A Miranville, … - Circulation, 2008 - Am Heart Assoc
Methods and Results— The present study, performed on human subcutaneous AT,
showed that ATMs from lean to overweight individuals are composed of distinct
macrophage subsets based on the expression of several cell surface markers: ...
Cited by 40 - Related articles - All 6 versions

Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human …

- endojournals.org
JM Bruun, AS Lihn, SB Pedersen, B … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc
Results: mRNA levels of specific macrophage markers (CD68 and CD14) are
correlated with adiposity in sc AT and visceral AT (P < 0.05). MCP-1 production
is higher in stromal-vascular cells vs. adipocytes (P < 0.01) and ...
Cited by 118 - Related articles - All 4 versions

Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of …

- shouxi.net
KE Inouye, H Shi, JK Howard, CH Daly, GM Lord … - Diabetes, 2007 - Am Diabetes Assoc
Macrophage recruitment to adipose tissue in obesity contributes to enhanced
adipose tissue inflammatory activity and thus may underlie obesity-associated
metabolic dysfunction. Obese adipose tissue exhibits increases in CC ...
Cited by 59 - Related articles - BL Direct - All 5 versions

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

- nih.gov
SP Weisberg, D Hunter, R Huber, J Lemieux, S … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig
The CC motif chemokine receptor–2 (CCR2) regulates monocyte and macrophage
recruitment and is necessary for macrophage-dependent inflammatory responses and
the development of atherosclerosis. Although adipose tissue expression and ...
Cited by 315 - Related articles - BL Direct - All 14 versions

Relationship between adipocyte size and adipokine expression and secretion

- endojournals.org
T Skurk, C Alberti-Huber, C Herder, H Hauner - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Results: The mean adipocyte volume of the four fractions ranged from 205 ± 146
to 1.077 ± 471 pl. There were strong linear correlations for the secretion of
adipokines over time. Secretion of leptin, IL-6, IL-8, TNF- , monocyte ...
Cited by 110 - Related articles - BL Direct - All 3 versions

T-cell accumulation and regulated on activation, normal T cell expressed and secreted …

- ahajournals.org
H Wu, S Ghosh, XD Perrard, L Feng, GE … - Circulation, 2007 - Am Heart Assoc
From the Section of Atherosclerosis and Vascular Medicine (HW, SG, XDP, JLP,
CMB), the Division of Nephrology (LF, GEG), and the Division of Diabetes,
Endocrinology and Metabolism (LC), Department of Medicine; the Section of ...
Cited by 98 - Related articles - All 15 versions

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

- nih.gov
JY Kim, E van de Wall, M Laplante, A Azzara, … - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig
1 Department of Cell Biology and 2 Department of Medicine, Albert Einstein
College of Medicine, New York, New York, USA. 3 Department of Anatomy and
Physiology, Laval University Hospital Centre Research Centre, Laval ...
Cited by 120 - Related articles - BL Direct - All 10 versions

Impact of visceral adipose tissue on liver metabolism Part I: Heterogeneity of adipose tissue …


M Lafontan, J Girard - Diabetes and Metabolism, 2008 - Elsevier
Excess visceral adipose tissue is associated with anomalies of blood glucose
homoeostasis, elevation of plasma triglycerides and low high-density lipoprotein
cholesterol that contribute to the later appearance of type 2 diabetes and ...
Cited by 8 - Related articles - All 2 versions


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