JE Ayala, DP Bracy, BM Julien, JN Rottman, PT Fueger … - Diabetes, 2007 - Am Diabetes Assoc Stimulation of nitric oxide–cGMP signaling results in vascular relaxation and increased muscle
glucose uptake. We show that chronically inhibiting cGMP hydrolysis with the
phosphodiesterase-5 inhibitor sildenafil improves energy balance and enhances in vivo ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►antonioaversa.net [PDF] A Aversa, R Bruzziches, C Vitale, G … - Expert Opin. Drug …, 2007 - informahealthcare.com Erectile dysfunction frequently represents a neurovascular complication of diabetes mellitus,
and it has been calculated that almost 50% of diabetic men will have erectile dysfunction within
6 years after diagnosis. Penile endothelial and smooth muscle cell dysfunction are due to ... Cited by 11 - Related articles - BL Direct - All 8 versions
- ►antonioaversa.net [PDF] A Aversa, R Bruzziches, EA Greco, M Pili, D … - Current diabetes …, 2008 - ingentaconnect.com Chair of Internal Medicine, Dept. Medical Pathophysiology, Sapienza University of Rome, Italy
Abstract: Diabetes mellitus (DM) is an established risk factor predisposing to male erectile dysfunction
(ED), and it has been calculated that more than 50% of diabetic men develop ED within ... Cited by 3 - Related articles - All 4 versions
- ►diabetesjournals.org JE Ayala, DP Bracy, OP McGuinness, DH Wasserman - Diabetes, 2006 - Am Diabetes Assoc Despite increased use of the hyperinsulinemic-euglycemic clamp to study insulin action in
mice, the effects of experimental parameters on the results obtained have not been
addressed. In our studies, we determined the influences of sampling sites, fasting ... Cited by 42 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org ED Berglund, CY Li, G Poffenberger, JE Ayala, PT … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Insulin action and hypoglycemic counter-regulatory and insulin secretory phenotypes
varied considerably in four inbred mouse strains. In vivo insulin secretion was greatest in
129X1/Sv mice, but the counter-regulatory response to hypoglycemia was blunted. FVB/N ... Cited by 9 - Related articles - All 5 versions
- ►antonioaversa.net [PDF] A Aversa, C Vitale, M Volterrani, A Fabbri, G Spera, … - Diabetic …, 2008 - pt.wkhealth.com Results: After 1 week, flow-mediated dilatation (FMD) improved significantly (> 50% compared
with baseline) in patients allocated to both sildenafil arms (62 and 64%, respectively). In patients
allocated to chronic sildenafil, a progressive increase in percentage of patients with FMD ... Cited by 21 - Related articles - BL Direct - All 7 versions
JE Ayala, DP Bracy, T Hansotia, G Flock, Y Seino, DH … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Compared with wild-type mice, chow and high fat–fed DIRKO mice exhibited decreased
fat and muscle mass associated with increased energy expenditure and ambulatory activity.
Clamp rates of glucose infusion (GIR), endogenous glucose production (endoR a ), and ... Cited by 9 - Related articles - BL Direct - All 5 versions
ED Berglund, CY Li, HA Bina, SE Lynes, MD Michael, … - Endocrinology, 2009 - Endocrine Soc Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator shown to improve glycemic
control. However, the molecular and functional mechanisms underlying FGF21-mediated improvements
in glycemic control are not completely understood. We examined FGF21 effects on insulin ... Cited by 3 - Related articles - All 3 versions
F Sommer, T Klotz, U Engelmann - 2007 - nature.com After sildenafil treatment and a subsequent non-medicated month, IIEF EF was normal in 29
of 48 (60.4%, 95% confidence interval [CI]: 45.3–74.2%) of the nightly group vs. 4 of 49
(8.2%, 95% CI: 2.3–19.6%) of the as-needed group. PSV improved by 11.2 cm/s (95% CI: ... Cited by 21 - Related articles - BL Direct - All 7 versions