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Scholar Results 1 - 10 of about 101 related to Ayala: Chronic treatment with sildenafil improves energy balance and insulin action in high.... (0.13 sec) 

Chronic treatment with sildenafil improves energy balance and insulin action in …


JE Ayala, DP Bracy, BM Julien, JN Rottman, PT Fueger … - Diabetes, 2007 - Am Diabetes Assoc
Stimulation of nitric oxide–cGMP signaling results in vascular relaxation and increased muscle
glucose uptake. We show that chronically inhibiting cGMP hydrolysis with the
phosphodiesterase-5 inhibitor sildenafil improves energy balance and enhances in vivo ...
Cited by 23 - Related articles - BL Direct - All 5 versions

Chronic sildenafil in men with diabetes and erectile dysfunction

- antonioaversa.net [PDF] 
A Aversa, R Bruzziches, C Vitale, G … - Expert Opin. Drug …, 2007 - informahealthcare.com
Erectile dysfunction frequently represents a neurovascular complication of diabetes mellitus,
and it has been calculated that almost 50% of diabetic men will have erectile dysfunction within
6 years after diagnosis. Penile endothelial and smooth muscle cell dysfunction are due to ...
Cited by 11 - Related articles - BL Direct - All 8 versions

Redefining the role of long-acting phosphodiesterase inhibitor tadalafil in the …

- antonioaversa.net [PDF] 
A Aversa, R Bruzziches, EA Greco, M Pili, D … - Current diabetes …, 2008 - ingentaconnect.com
Chair of Internal Medicine, Dept. Medical Pathophysiology, Sapienza University of Rome, Italy
Abstract: Diabetes mellitus (DM) is an established risk factor predisposing to male erectile dysfunction
(ED), and it has been calculated that more than 50% of diabetic men develop ED within ...
Cited by 3 - Related articles - All 4 versions

Considerations in the design of hyperinsulinemic-euglycemic clamps in the …

- diabetesjournals.org
JE Ayala, DP Bracy, OP McGuinness, DH Wasserman - Diabetes, 2006 - Am Diabetes Assoc
Despite increased use of the hyperinsulinemic-euglycemic clamp to study insulin action in
mice, the effects of experimental parameters on the results obtained have not been
addressed. In our studies, we determined the influences of sampling sites, fasting ...
Cited by 42 - Related articles - BL Direct - All 7 versions

Glucose metabolism in vivo in four commonly used inbred mouse strains

- diabetesjournals.org
ED Berglund, CY Li, G Poffenberger, JE Ayala, PT … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Insulin action and hypoglycemic counter-regulatory and insulin secretory phenotypes
varied considerably in four inbred mouse strains. In vivo insulin secretion was greatest in
129X1/Sv mice, but the counter-regulatory response to hypoglycemia was blunted. FVB/N ...
Cited by 9 - Related articles - All 5 versions

Chronic administration of Sildenafil improves markers of endothelial function in …

- antonioaversa.net [PDF] 
A Aversa, C Vitale, M Volterrani, A Fabbri, G Spera, … - Diabetic …, 2008 - pt.wkhealth.com
Results: After 1 week, flow-mediated dilatation (FMD) improved significantly (> 50% compared
with baseline) in patients allocated to both sildenafil arms (62 and 64%, respectively). In patients
allocated to chronic sildenafil, a progressive increase in percentage of patients with FMD ...
Cited by 21 - Related articles - BL Direct - All 7 versions

Insulin action in the double incretin receptor knockout mouse


JE Ayala, DP Bracy, T Hansotia, G Flock, Y Seino, DH … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Compared with wild-type mice, chow and high fat–fed DIRKO mice exhibited decreased
fat and muscle mass associated with increased energy expenditure and ambulatory activity.
Clamp rates of glucose infusion (GIR), endogenous glucose production (endoR a ), and ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose …


ED Berglund, CY Li, HA Bina, SE Lynes, MD Michael, … - Endocrinology, 2009 - Endocrine Soc
Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator shown to improve glycemic
control. However, the molecular and functional mechanisms underlying FGF21-mediated improvements
in glycemic control are not completely understood. We examined FGF21 effects on insulin ...
Cited by 3 - Related articles - All 3 versions

[PDF] Testosterone: estradiol ratio changes associated with long-term tadalafil …


EA Greco, M Pili, R Bruzziches, G Corona, G … - Journal of Sexual …, 2006 - antonioaversa.net
Blackwell Publishing IncMalden, USAJSMJournal of Sexual Medicine1743-6095© 2006 International
Society for Sexual Medicine200634716722Original ArticleLong-Term Endocrine Effects of TadalafilGreco
et al. ... Testosterone:Estradiol Ratio Changes Associated with Long-Term
Cited by 14 - Related articles - View as HTML - BL Direct - All 4 versions

Improved spontaneous erectile function in men with mild-to-moderate arteriogenic …


F Sommer, T Klotz, U Engelmann - 2007 - nature.com
After sildenafil treatment and a subsequent non-medicated month, IIEF EF was normal in 29
of 48 (60.4%, 95% confidence interval [CI]: 45.3–74.2%) of the nightly group vs. 4 of 49
(8.2%, 95% CI: 2.3–19.6%) of the as-needed group. PSV improved by 11.2 cm/s (95% CI: ...
Cited by 21 - Related articles - BL Direct - All 7 versions


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