MM Martinic, AE Juedes, D Bresson, D Homann, K … - Diabetes, 2007 - Am Diabetes Assoc During an autoimmune process, the autoaggressive response spreads from the initiating autoantigen
to other antigens expressed in the target organ. Based on evidence from experimental models
for multiple sclerosis, such “antigenic spreading” can play an important role in the ... Cited by 3 - Related articles - BL Direct - All 7 versions
- ►adisonline.com [PDF] M von Herrath, D Rottembourg, D Bresson - BioDrugs, 2006 - ingentaconnect.com Page 1. Biodrugs 2006; 20 (6): 341-350 N OVEL T HERAPEUTIC S TRATEGIES
1173-8804/06/0006-0341/$39.95/0 2006 Adis Data Information BV. All rights reserved. Progress
in the Development of Immune-Based Therapies for Type 1 Diabetes Mellitus ... Cited by 2 - Related articles - BL Direct - All 4 versions
D Bresson, M von Herrath - Drug Discovery Today: Disease Mechanisms, 2004 - Elsevier Type 1 diabetes (T1D) is considered to be an autoimmune disease, where auto-aggressive T
cells infiltrate the islets of Langerhans in the pancreas and play an important role by specifically
destroying the insulin-producing beta-cell population. To date numerous lines of ... Cited by 2 - Related articles
B Denes, V Krausova, N Fodor, T Timiryasova … - Journal of …, 2005 - journals.lww.com Oral administration of autoantigens and allergens can delay or suppress clinical disease in experimental
autoimmune and allergic disorders. However, repeated feeding of large amounts of the tolerogens
is required over long periods and is only partially effective in animals systemically ... Cited by 3 - Related articles - BL Direct - All 5 versions
CM Filippi, EA Estes, JE Oldham, MG … - The Journal of Clinical …, 2009 - pubmedcentral.nih.gov Type 1 diabetes (T1D) is an autoimmune disease that is caused by the destruction of
insulin-producing β cells. Viral infections induce immune responses that can damage β cells
and promote T1D or on the other hand prevent the development of the disease. However, ... Cited by 1 - Related articles - All 7 versions
CM Filippi, MG von Herrath - Diabetes, 2008 - Am Diabetes Assoc The most popular hypothesis circulating within and beyond the scientific community is that viral
infections enhance or elicit autoimmune disorders such as type 1 diabetes. Indeed, viruses can
injure β-cells and have been isolated in pancreatic tissues from diabetic patients. ... Cited by 8 - Related articles - All 8 versions
LM Bekris, RA Jensen, E Lagerquist, TR Hall, … - Diabetic …, 2007 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 3 - Related articles - BL Direct - All 5 versions
D Li, S Wen Zhu, D Juan Liu, G Liang Liu - 世界胃肠病学杂志: 英文版, 2005 - wjg.wjgnet.com Methods: Non-obese diabetic (NOD) mice were used as experiment group and BALB/c mice
as non-diabetic prone model. Immunohistochemistry method was used to evaluate the expression
of IP-10 in the pancreas of NOD mice and BALB/c mice. Immunoelectron microscope was ... Cited by 3 - Related articles - Cached - BL Direct - All 8 versions
- ►nih.gov KS Goudy, B Wang, R Tisch - Clinical Immunology, 2008 - Elsevier Type 1 diabetes (T1D) is characterized by the T cell mediated destruction of the insulin-producing
β cells. Antigen-specific immunotherapies are used to selectively tolerize β cell-specific pathogenic
T cells either directly, or indirectly through the induction of immunoregulatory T cells. A ... Cited by 3 - Related articles - All 4 versions
- ►diabetesjournals.org V Butty, C Campbell, D Mathis, C Benoist - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The unfolding of type 1 diabetes involves a number of steps: defective immunological
tolerance, priming of anti-islet autoimmunity, and destruction of insulin-producing β-cells. A number
of genetic loci contribute to susceptibility to type 1 diabetes, but it is unclear which stages ... Cited by 4 - Related articles - All 5 versions
