RJM Coward, GI Welsh, A Koziell, S Hussain, R … - Diabetes, 2007 - Am Diabetes Assoc The leading causes of albuminuria and end-stage renal failure are secondary to abnormalities
in the production or cellular action of insulin, including diabetes and hyperinsulinemic metabolic
syndrome. The human glomerular podocyte is a critical cell for maintaining the filtration ... Cited by 20 - Related articles - BL Direct - All 5 versions
RJM Coward, GI Welsh, J Yang, C Tasman, R Lennon, … - Diabetes, 2005 - Am Diabetes Assoc Microalbuminuria is significant both as the earliest stage of diabetic nephropathy and as an independent
cardiovascular risk factor in nondiabetic subjects, in whom it is associated with insulin
resistance. The link between disorders of cellular insulin metabolism and albuminuria has ... Cited by 36 - Related articles - BL Direct - All 11 versions
T Tejada, P Catanuto, A Ijaz, JV Santos, X Xia, P … - Kidney International, 2008 - nature.com Loss of podocytes by apoptosis characterizes the early stages of diabetic nephropathy. To examine
its mechanism we studied glomeruli and podocytes isolated from db/db mice with early diabetic
nephropathy and albuminuria. Phosphorylation of AKT (protein kinase B, a key survival ... Cited by 7 - Related articles - BL Direct - All 4 versions
R Lennon, D Pons, MA Sabin, C Wei, JP Shield, … - Nephrology Dialysis …, 2009 - ERA-EDTA Background. Cellular insulin resistance is the hallmark of type 2 diabetes and predominantly
affects adipose and muscle cells. The saturated free fatty acid palmitate is elevated in
insulin-resistant states and may directly contribute to cellular insulin resistance. A ... Cited by 2 - Related articles - All 3 versions
A Ijaz, T Tejada, P Catanuto, X Xia, SJ Elliot, O Lenz, A … - Kidney International, 2008 - nature.com C-jun N-terminal kinase (JNK) regulates both the development of insulin resistance and
inflammation. Podocytes of the widely used db/db mouse model of diabetic nephropathy lose
their ability to respond to insulin as albuminuria develops, in comparison to control db/+ ... Cited by 3 - Related articles - All 4 versions
JJ Li, SJ Kwak, DS Jung, JJ Kim, TH Yoo, DR Ryu, SH … - Kidney International, 2007 - nature.com Glomerular visceral epithelial cells, namely podocytes, are highly specialized cells and give
rise to primary processes, secondary processes, and finally foot processes. The foot processes
of neighboring podocytes interdigitate, leaving between them filtration slits. These are ... Cited by 16 - Related articles - BL Direct - All 3 versions
A Pätäri-Sampo, P Ihalmo, H Holthöfer - Annals of medicine, 2006 - informahealthcare.com For more than three decades, the molecular composition of the interpodocyte slit diaphragm
of the glomerular filtration barrier has remained elusive. The first electron microscopic studies
described the slit diaphragm as a porous, 'zipper‐like' structure, but it was not until 1998 ... Cited by 31 - Related articles - BL Direct - All 6 versions
H Laakkonen, T Lönnqvist, J Uusimaa, E Qvist, L … - Pediatric Nephrology, 2006 - Springer Abstract Congenital nephrotic syndrome of the Finnish type (NPHS1, CNF) is an autosomal recessively
inherited disease occurring due to mutations in the nephrin gene (NPHS1). Two main Finnish
mutations exist: Fin-major and minor, which both cause a lack of nephrin and ab- sence of ... Cited by 10 - Related articles - BL Direct - All 4 versions
TS Ha - Nephrology, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 10 - Related articles - BL Direct - All 3 versions
Y Morikawa, T Komori, T Hisaoka, H Ueno, T Kitamura, … - Neuroscience, 2007 - Elsevier In mammalians, the transduction of external stimuli from environments, such as odor, light, and
sound, first takes place in the specific sensory organs: these senses are initiated by specialized
primary sensory cells of the sensory organs. The primary sensory cells activated by ... Cited by 4 - Related articles - All 3 versions
