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Scholar Results 1 - 10 of about 101 related to Ku: Insulin-Expressing Colonies Developed From Murine Embryonic Stem Cell–Derived Progenitors. (0.08 sec) 

Insulin-Expressing Colonies Developed From Murine Embryonic Stem Cell– …


HT Ku, J Chai, YJ Kim, P White, S Purohit-Ghelani, KH … - Diabetes, 2007 - Am Diabetes Assoc
Previous studies describe a unique culture method for the commitment of murine embryonic
stem cells to early endocrine pancreata. In this report, early pancreatic-like β-cell progenitors
were enriched and a colony assay devised to allow these progenitors to differentiate into ...
Cited by 7 - Related articles - BL Direct - All 5 versions

不同培养时间对 NIT-1 细胞胰岛素分泌及相关基因表达的影响


李英, 杨川, 严励, 傅静奕, 王川 - 中国病理生理杂志, 2008 - cqvip.com
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登录 注册 客服中心. 维普资讯 中文期刊·专业文章. 维普专业检索. 基础医学 >> 中国病理生理杂志 >>
2008年24卷9期 >> 摘要. 不同培养时间对NIT-1细胞胰岛素分泌及相关基因表达的影响. ...
Related articles - All 7 versions

Insulin Gene Expression Is Regulated by DNA Methylation


A Kuroda, TA Rauch, I Todorov, HT Ku, IH Al-Abdullah, … - 2009 - pubmedcentral.nih.gov
Genomic DNA samples from several tissues were bisulfite-treated and sequenced which revealed
that cytosine-guanosine dinucleotide (CpG) sites in both the mouse Ins2 and human INS promoters
are uniquely demethylated in insulin-producing pancreatic beta cells. Methylation of ...
Related articles - All 5 versions

Generation of embryonic stem cells from mouse insulin I promoter-green …


WM Milewski, KA Temple, RL Wesselschmidt, M … - In Vitro Cellular & …, 2009 - Springer
Abstract Insulin-secreting pancreatic beta cells play a key role in the pathogenesis of diabetes
mellitus. Potential new treatments for this disease include cell-replacement thera- pies using
embryonic stem cells (ESCs). We have generated ESCs from a transgenic mouse model, ...
Related articles - All 2 versions

Activin A-Induced Differentiation of Embryonic Stem Cells into Endoderm and …


S Sulzbacher, IS Schroeder, TT Truong, AM … - Stem Cell Reviews and …, 2009 - Springer
Abstract The differentiation of murine and human embry- onic stem (ES) cells into pancreatic
cell types has been shown by several methods including spontaneous differen- tiation, formation
of multi-lineage progenitors, lineage selection or transgene expression. However, these ...
Related articles - All 2 versions

Both Pdx-1 and NeuroD1 genes are requisite for the maintenance of insulin gene …


K Saitoh, E Yamato, S Miyazaki, JI Miyazaki - Diabetes Research and Clinical …, 2007 - Elsevier
Embryonic stem (ES) cells can differentiate into many cell types. Recent reports have shown
that ES cells can differentiate into insulin-producing cells. We have established an ES cell line
in which exogenous Pdx-1 expression was precisely regulated by the Tet-off system ...
Cited by 2 - Related articles - All 8 versions

Pancreatic Progenitor Cells--Recent Studies

- endojournals.org
HT Ku - Endocrinology, 2008 - Endocrine Soc
Past studies of pancreatic progenitor cell biology relied mostly on histological analyses. Recent
studies, using genetic labeling and tracing of progenitors, direct single cell analyses, colony
assays, and enrichment of the minor population of progenitor cells through the use of cell ...
Cited by 1 - Related articles - All 5 versions

Copper deprivation in rats induces islet hyperplasia and hepatic metaplasia in the …


D Tosh, C Shen, M Alison, C Sarraf, J Slack - Biology of the Cell, 2007 - biolcell.org
1 Present address: Stem Cell Program, Genomics Research Centre, Academia Sinica, Taipei
115, Taiwan. ... 4 To whom correspondence should be addressed (email jmwslack@bath.ac.
uk). ... Key words: copper deprivation, hepatocyte metaplasia, hyperplasia, insulin, ...
Cited by 2 - Related articles - Cached - All 11 versions

[CITATION] Chuva de Sousa Lopes, SM, et al.(2007). Derivation of pluripotent epiblast stem …


IG Brons, LE Smithers, MW Trotter, P Rugg-Gunn, B … - Nature
Cited by 2 - Related articles

Directed Differentiation of Mouse Embryonic Stem Cells into Pancreatic-Like or …


E McKiernan, L O'Driscoll, M Kasper, N Barron, F … - Tissue …, 2007 - liebertonline.com
Pancreatic-Like or Neuronal- and Glial-Like Phenotypes ... EADAOIN M C KIERNAN, B.Sc.,
Ph.D., 1,* LORRAINE O'DRISCOLL, B.Sc., M.Sc., Ph.D., ... MICHAEL KASPER, B.Sc., Ph.D.,
2 NIALL BARRON, B.Sc., Ph.D., 1 ... FINBARR O'SULLIVAN, B.Sc., Ph.D., 1 and MARTIN ...
Cited by 4 - Related articles - BL Direct - All 3 versions


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