- ►shouxi.net NA Kaniuk, M Kiraly, H Bates, M Vranic, A … - Diabetes, 2007 - Am Diabetes Assoc Diabetes-induced oxidative stress can lead to protein misfolding and degradation
by the ubiquitin-proteasome system. This study examined protein ubiquitination
in pancreatic sections from Zucker diabetic fatty rats. We observed large ... Cited by 20 - Related articles - BL Direct - All 6 versions
- ►endojournals.org BJ Marsh, C Soden, C Alarcon, BL Wicksteed … - Molecular Endocrinology, 2007 - Endocrine Soc Endocrine cells are continually regulating the balance between hormone
biosynthesis, secretion, and intracellular degradation to ensure that cellular
hormone stores are maintained at optimal levels. In pancreatic ß-cells, ... Cited by 14 - Related articles - BL Direct - All 3 versions
J Szeto, NA Kaniuk, V Canadien, R Nisman, N … - Autophagy - ncbi.nlm.nih.gov Misfolded proteins can be directed into cytoplasmic aggregates such as
aggresomes and dendritic cell aggresome-like induced structures (DALIS). DALIS
were originally identified in lipopolysaccharide-stimulated dendritic cells ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►cell.com C Ebato, T Uchida, M Arakawa, M Komatsu, T … - Cell metabolism, 2008 - Elsevier Autophagy is an evolutionarily conserved machinery for bulk degradation of
cytoplasmic components. Here, we report upregulation of autophagosome formation
in pancreatic beta cells in diabetic db/db and in nondiabetic high-fat-fed ... Cited by 15 - Related articles - All 7 versions
E Shvets, Z Elazar - Autophagy, 2008 - ncbi.nlm.nih.gov LC3 is a widely used marker of autophagosomes in mammalian cells. However, in
addition to its autophagosomal localization, GFP-LC3 is often found associated
with protein aggregates that are formed in an autophagy-independent manner. ... Cited by 7 - Related articles - All 3 versions
HS Jung, KW Chung, J Won Kim, J Kim, M … - Cell metabolism, 2008 - Elsevier Autophagy is a cellular degradation-recycling system for aggregated proteins and
damaged organelles. Although dysregulated autophagy is implicated in various
diseases including neurodegeneration, its role in pancreatic β cells and ... Cited by 17 - Related articles - All 5 versions
K Fujimoto, PT Hanson, H Tran, EL Ford, Z … - Journal of Biological Chemistry, 2009 - ASBMB There are three types of cell death; apoptosis, necrosis, and autophagy. The
possibility that activation of the macroautophagy (autophagy) pathway may
increase beta cell death is addressed in this study. Increased autophagy ... Cited by 1 - Related articles - All 3 versions
EM Carneiro, MQ Latorraca, E Araujo, M Beltrá … - The Journal of Nutritional Biochemistry, 2009 - Elsevier Taurine is a conditionally essential amino acid for human that is involved in
the control of glucose homeostasis; however, the mechanisms by which the amino
acid affects blood glucose levels are unknown. Using an animal model, we ... Cited by 1 - Related articles - All 5 versions
L Sang-Hoon, L Hyun-Young, K So-Yeon, L In … - Diabetes research and clinical practice, 2004 - Elsevier Uncoupling protein 2 (UCP2) is up-regulated in pancreatic beta cells when
exposed to long-term high glucose or free fatty acids, which results in impaired
glucose-induced insulin secretion (GIIS). We have evaluated whether taurine ... Cited by 3 - Related articles - All 5 versions
AJ Meijer, P Codogno - Autophagy - ncbi.nlm.nih.gov 1: Autophagy. 2007 Sep-Oct;3(5):523-6. Epub 2007 May 18. Macroautophagy:
protector in the diabetes drama? Meijer AJ, Codogno P. ... Cited by 6 - Related articles - BL Direct - All 3 versions
