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Scholar Results 1 - 10 of about 101 related to Šebeková: Renal effects of S18886 (terutroban), a TP receptor antagonist, in an experimental.... (0.11 sec) 

Renal effects of S18886 (terutroban), a TP receptor antagonist, in an experimental …


K Šebeková, T Eifert, A Klassen, A Heidland, K Amann - Diabetes, 2007 - Am Diabetes Assoc
Thromboxane A 2 (TxA 2 ) is assumed to contribute to the development of diabetes
complications, including nephropathy. We investigated whether the selective thromboxane-prostanoid
endoperoxide receptor antagonist, S18886, ameliorates renal damage in ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Functional and partial morphological regression of established renal injury in the …


B Analyses, R Histology, B Weight, K Weight, SBPR … - Am J Nephrol, 2009 - content.karger.com
Background/Aims: In experimental nephropathies, inhibitors of the renin-angiotensin-system
(RAS) halted the progression, or even induced a regression in renal injury. We studied the potential
of the angiotensin-converting enzyme (ACE) inhibitor perindopril and the angiotensin ...
Cited by 2 - Related articles - All 4 versions

The selective TP receptor antagonist, S18886 (terutroban), attenuates renal …


K Šebeková, A Ramuscak, P Boor, A Heidland, K … - Am J Nephrol, 2008 - content.karger.com
Background/Aims: Thromboxane receptors play a decisive role in the renovascular actions of
angiotensin II. We studied the efficacy of the selective thromboxane receptor antagonist,
S18886, in the retardation of renal damage in the double transgenic rats (dTGR), ...
Cited by 4 - Related articles - BL Direct - All 5 versions

The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and …


S Xu, B Jiang, KA Maitland, H Bayat, J Gu, JL Nadler, S … - Diabetes, 2006 - Am Diabetes Assoc
Arachidonic acid metabolites, some of which may activate thromboxane A 2 receptors (TPr) and
contribute to the development of diabetes complications, including nephropathy, are elevated
in diabetes. This study determined the effect of blocking TPr with S18886 or inhibiting ...
Cited by 38 - Related articles - BL Direct - All 7 versions

Role of thromboxane receptors in the dipsogenic response to central angiotensin II

- physiology.org
C Kitiyakara, WJ Welch, JG Verbalis, CS … - American Journal of …, 2002 - Am Physiological Soc
Central angiotensin II (ANG II) regulates thirst. Because thromboxane A 2 -prostaglandin H 2
(TP) receptors are expressed in the brain and mediate some of the effects of ANG II in the
vasculature, we investigated the hypothesis that TP receptors mediate the drinking ...
Cited by 7 - Related articles - BL Direct - All 3 versions

Thromboxane receptors in human kidney tissues


GP Brownab, RC Venuto - Prostaglandins, 1999 - Elsevier
Thromboxane (TX) A 2 effects in the kidneys include contraction of glomerular mesangial cells
and intrarenal vascular tissue. A kidney cDNA encoding a TX receptor expressed in rat renal
glomeruli and rat renal arterial smooth muscle cells has been reported. However, TXA 2 ...
Cited by 9 - Related articles - All 6 versions

Thromboxane blockade reduces blood pressure and progression of renal failure …


R Larivière, C Moreau, MÈ Rodrigue, M Lebel - Prostaglandins, Leukotrienes & …, 2004 - Elsevier
This study was designed to investigate the role of eicosanoids, thromboxane A 2 (TXA 2 ) and
prostacyclin (PGI 2 ) as well as their relationship with endothelin-1 (ET-1) in the pathogenesis
of renal parenchymal hypertension. Uremic rats were prepared by renal mass ablation ...
Cited by 10 - Related articles - All 9 versions

糖肾方对糖尿病肾病大鼠的保护作用


张浩军, 李平, 赵静波, 赵世萍, 罗月会, 沙洪, 郭景珍 … - 北京中医药大学学报, 2009 - cqvip.com
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Effect of pharmaceutical interventions targeting thromboxane receptors and …


KS Sakariassen, P Alberts, P Fontana, J Mann, H … - Future Cardiol., 2009 - Future Medicine
The present review focuses on the roles of thromboxane A 2 (TxA 2 ) in arterial thrombosis,
atherogenesis, vascular stent-related ischemic events and renal proteinuria. Particular emphasis
is laid on therapeutic interventions targeting the TxA 2 (TP) receptors and TxA 2 synthase ( ...
Related articles - All 4 versions

[PDF] Distinct Roles for Basal and Induced COX-2 in Podocyte Injury


H Cheng, X Fan, Y Guan, GW Moeckel, R Zent, … - Journal of the American …, 2009 - zhshen.com.cn
ABSTRACT Transgenic mice that overexpress cyclooxygenase-2 (COX-2) selectively in podocytes
are more suscep- tible to glomerular injury by adriamycin and puromycin (PAN). To investigate
the potential roles of COX-2 metabolites, we studied mice with selective deletion of ...
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