K Šebeková, T Eifert, A Klassen, A Heidland, K Amann - Diabetes, 2007 - Am Diabetes Assoc Thromboxane A 2 (TxA 2 ) is assumed to contribute to the development of diabetes
complications, including nephropathy. We investigated whether the selective thromboxane-prostanoid
endoperoxide receptor antagonist, S18886, ameliorates renal damage in ... Cited by 11 - Related articles - BL Direct - All 5 versions
B Analyses, R Histology, B Weight, K Weight, SBPR … - Am J Nephrol, 2009 - content.karger.com Background/Aims: In experimental nephropathies, inhibitors of the renin-angiotensin-system
(RAS) halted the progression, or even induced a regression in renal injury. We studied the potential
of the angiotensin-converting enzyme (ACE) inhibitor perindopril and the angiotensin ... Cited by 2 - Related articles - All 4 versions
K Šebeková, A Ramuscak, P Boor, A Heidland, K … - Am J Nephrol, 2008 - content.karger.com Background/Aims: Thromboxane receptors play a decisive role in the renovascular actions of
angiotensin II. We studied the efficacy of the selective thromboxane receptor antagonist,
S18886, in the retardation of renal damage in the double transgenic rats (dTGR), ... Cited by 4 - Related articles - BL Direct - All 5 versions
S Xu, B Jiang, KA Maitland, H Bayat, J Gu, JL Nadler, S … - Diabetes, 2006 - Am Diabetes Assoc Arachidonic acid metabolites, some of which may activate thromboxane A 2 receptors (TPr) and
contribute to the development of diabetes complications, including nephropathy, are elevated
in diabetes. This study determined the effect of blocking TPr with S18886 or inhibiting ... Cited by 38 - Related articles - BL Direct - All 7 versions
- ►physiology.org C Kitiyakara, WJ Welch, JG Verbalis, CS … - American Journal of …, 2002 - Am Physiological Soc Central angiotensin II (ANG II) regulates thirst. Because thromboxane A 2 -prostaglandin H 2
(TP) receptors are expressed in the brain and mediate some of the effects of ANG II in the
vasculature, we investigated the hypothesis that TP receptors mediate the drinking ... Cited by 7 - Related articles - BL Direct - All 3 versions
GP Brownab, RC Venuto - Prostaglandins, 1999 - Elsevier Thromboxane (TX) A 2 effects in the kidneys include contraction of glomerular mesangial cells
and intrarenal vascular tissue. A kidney cDNA encoding a TX receptor expressed in rat renal
glomeruli and rat renal arterial smooth muscle cells has been reported. However, TXA 2 ... Cited by 9 - Related articles - All 6 versions
R Larivière, C Moreau, MÈ Rodrigue, M Lebel - Prostaglandins, Leukotrienes & …, 2004 - Elsevier This study was designed to investigate the role of eicosanoids, thromboxane A 2 (TXA 2 ) and
prostacyclin (PGI 2 ) as well as their relationship with endothelin-1 (ET-1) in the pathogenesis
of renal parenchymal hypertension. Uremic rats were prepared by renal mass ablation ... Cited by 10 - Related articles - All 9 versions
KS Sakariassen, P Alberts, P Fontana, J Mann, H … - Future Cardiol., 2009 - Future Medicine The present review focuses on the roles of thromboxane A 2 (TxA 2 ) in arterial thrombosis,
atherogenesis, vascular stent-related ischemic events and renal proteinuria. Particular emphasis
is laid on therapeutic interventions targeting the TxA 2 (TP) receptors and TxA 2 synthase ( ... Related articles - All 4 versions
H Cheng, X Fan, Y Guan, GW Moeckel, R Zent, … - Journal of the American …, 2009 - zhshen.com.cn ABSTRACT Transgenic mice that overexpress cyclooxygenase-2 (COX-2) selectively in podocytes
are more suscep- tible to glomerular injury by adriamycin and puromycin (PAN). To investigate
the potential roles of COX-2 metabolites, we studied mice with selective deletion of ... Related articles - View as HTML - All 4 versions