- ►diabetesjournals.org DJ Michael, W Xiong, X Geng, P Drain, RH … - Diabetes, 2007 - Am Diabetes Assoc In healthy individuals, plasma insulin levels oscillate in both fasting and fed
states. Numerous studies of isolated pancreata and pancreatic islets support the
hypothesis that insulin oscillations arise because the underlying rate of ... Cited by 8 - Related articles - BL Direct - All 5 versions
V Shanmuganathan, 2008 - digitallibrary.usc.edu Page 1. A NOVEL CONSTRUCT TO STUDY THE PULSATILITY OF INSULIN SECRETION IN SINGLE
CELLS, ISLETS, AND WHOLE PANCREAS by Vivekanandan Shanmuganathan ... Related articles - View as HTML - All 2 versions
J Sågetorp - uu.diva-portal.org Dissertation presented at Uppsala University to be publicly examined in B21,
BMC, Husargatan 3, Uppsala, Saturday, March 21, 2009 at 09:15 for the degree of
Doctor of Philosophy (Faculty of Medicine). The examination will be ... Related articles - View as HTML - All 2 versions
- ►nih.gov MA Ravier, T Tsuboi, GA Rutter - Methods, 2008 - Elsevier Ca 2+ ions are the most ubiquitous second messenger found in all cells, and play
a significant role in controlling regulated secretion from neurons, endocrine,
neuroendocrine and exocrine cells. Here, we describe microscopic techniques ... Related articles - All 6 versions
S Misler - Advances in Physiology Education, 2009 - Am Physiological Soc Stimulus-secretion coupling (SSC) in endocrine cells remains underappreciated as
a subject for the study/teaching of general physiology. In the present article,
we review key new electrophysiological, electrochemical, and fluorescence ... Related articles - All 2 versions
M Braun, R Ramracheya, PR Johnson, P … - Annals of the New York Academy of Sciences, 2009 - interscience.wiley.com Pancreatic β-cells secrete insulin in response to elevated blood glucose via Ca
2+ -dependent fusion of secretory granules with the plasma membrane (regulated
exocytosis). While exocytosis has been extensively investigated in rodent ... Related articles - All 4 versions
R Ivarsson, S Obermuller, GA Rutter, J … - Traffic, 2004 - interscience.wiley.com Glucose-evoked insulin secretion exhibits a biphasic time course and is
associated with accelerated intracellular granule movement. We combined live
confocal imaging of EGFP-labelled insulin granules with capacitance ... Cited by 17 - Related articles - BL Direct - All 3 versions
- ►nih.gov DJ Michael, X Geng, NX Cawley, YP Loh, CJ … - Biophysical Journal, 2004 - Elsevier We compared secretion kinetics for four different fluorescent cargo proteins,
each targeted to the lumen of insulin secretory vesicles. Upon stimulation,
individual vesicles displayed one of four distinct patterns of fluorescence ... Cited by 27 - Related articles - BL Direct - All 8 versions
S Misler, AM Silva, D Barnett, AS Dickey - Channels (Austin, Tex.), 2009 - ncbi.nlm.nih.gov In response to depolarizations that open voltage dependent Ca(2+) channels
single porcine beta-cells display heterogeneous time courses of exocytosis. Some
cells display phasic exocytosis that is triggered by individual or short ... Cited by 1 - Related articles - All 3 versions
- ►physiology.org AV Matveyenko, JD Veldhuis, PC Butler - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc It has previously been shown that insulin is secreted in discrete secretory
bursts by sampling directly from the portal vein in the dog and humans.
Deficient pulsatile insulin secretion is the basis for impaired insulin ... Cited by 1 - Related articles - All 4 versions