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Scholar Results 1 - 10 of about 101 related to Fu: Evidence that Rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is a type.... (0.12 sec) 

Evidence that Rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is …

- diabetesjournals.org
M Fu, MM Sabra, C Damcott, TI Pollin, L Ma, S Ott, JC … - Diabetes, 2007 - Am Diabetes Assoc
Rho guanine nucleotide exchange factor 11 (ARHGEF11), located on chromosome 1q21, is
involved in G protein signaling and is a pathway known to play a role in both insulin secretion
and action. We genotyped 52 single nucleotide polymorphims (SNPs) in ARHGEF11 and ...
Cited by 10 - Related articles - BL Direct - All 8 versions

Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes mellitus …


L Ma, RL Hanson, LN Que, AMG Cali, M Fu, JL Mack … - Medicine, … - Am Diabetes Assoc
Received for publication 9 May 2006 and accepted in revised form 22 January 2007. ... Lijun
Ma1, Robert L. Hanson1, Lorem N. Que1, Anna MG Cali1, Mao Fu2, Janel L. Mack1, Aniello
M. Infante1, Sayuko Kobes1, Clifton Bogardus1, Alan R. Shuldiner2, and Leslie J. Baier1
Cited by 6 - Related articles - All 3 versions

[CITATION] the International Type 2 Diabetes 1q Consortium: Variation within the gene …


E Zeggini, CM Damcott, KMA HansonRL, NW Rayner, … - Diabetes, 2006
Cited by 6 - Related articles

Design and analysis of genetic association studies to finely map a locus identified …


RL Hanson, WC Knowler - Annals of Human Genetics, 2008 - interscience.wiley.com
Association studies are often used to finely map quantitative trait loci identified by linkage
analysis. Once a polymorphism associated with the trait has been identified, it may be useful
to conduct linkage analyses which adjust for this polymorphism to determine the extent to ...
Cited by 5 - Related articles - BL Direct - All 4 versions

Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on …

- diabetesjournals.org
L Ma, RL Hanson, LN Que, AMG Cali, M Fu, JL Mack, … - Diabetes, 2007 - Am Diabetes Assoc
A prior genome-wide linkage scan in Pima Indians indicated a young-onset (aged <45
years) type 2 diabetes susceptibility locus on chromosome 1q21-q23. ARHGEF11, which encodes
the Rho guanine nucleotide exchange factor 11, was analyzed as a positional candidate ...
Cited by 3 - Related articles - BL Direct - All 8 versions

[CITATION] Disturbances in glucose-tolerance, insulin-release and stress-induced …


A Pereverzev, M Mikhna, R Vajna, C Gissel, M Henry, … - Mol. Endocrinol., 2002
Cited by 10 - Related articles

Mice Lacking Cav2. 3 (α1E) Calcium Channel Exhibit Hyperglycemia


Y Matsuda, H Saegusa, S Zong, T Noda, T Tanabe - … and Biophysical Research …, 2001 - Elsevier
To investigate the functional role of Ca v 2.3 channel in glucose homeostasis, we performed
in vivo glucose tolerance and insulin tolerance tests together with stress-induced glucose release
tests using mice deficient in Ca v 2.3 channel (Ca v 2.3−/−). The Ca v 2.3−/− mice were ...
Cited by 18 - Related articles - BL Direct - All 6 versions

A functional Tyr1306Cys variant in LARG is associated with increased insulin …


P Kovacs, M Stumvoll, C Bogardus, RL Hanson, LJ … - Diabetes, 2006 - Am Diabetes Assoc
Diminished insulin sensitivity is a characteristic feature of type 2 diabetes. Inhibition of insulin
action, resulting in reduced skeletal muscle glucose uptake, is mediated in part through stimulation
of RhoA activity. One regulator of RhoA activity is leukemia-associated Rho guanine ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Genetic variants in the leukemia-associated Rho guanine nucleotide exchange …

- eje-online.org
C Holzapfel, N Klopp, H Grallert, C Huth, C Gieger, C … - European Journal of …, 2007 - EFES
Methods: Sequencing of Tyr1306Cys, which was of functional relevance in Pima Indians, in 48
randomly selected individuals and genotyping of 11 additional LARG SNPs in 1653 subjects
were performed. Four linkage disequilibrium (LD) blocks (r 2 0.8) were established and ...
Related articles - BL Direct - All 7 versions

Ric-8B Modulates the Function of Alpha Subunit of Go


SH Kim, SH Ghil - 대한의생명과학회지, 2007 - dbpia.co.kr
Heterotrimeric GTP binding proteins (G proteins) mediate signal generated by neurotransmitter
and hormones. Among all G proteins, Go is the most abundant in brain but its role in brain is
not clearly understood. To determine the function of the alpha subunit of Go (Goα), we ...
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