DE Befroy, KF Petersen, S Dufour, GF Mason … - Diabetes, 2007 - Am Diabetes Assoc Insulin resistance is the best predictor for the development of diabetes in
offspring of type 2 diabetic patients, but the mechanism responsible for it
remains unknown. Recent studies have demonstrated increased ... Cited by 68 - Related articles - BL Direct - All 6 versions
M Mogensen, K Sahlin, M Fernström, D … - Diabetes, 2007 - Am Diabetes Assoc We tested the hypothesis of a lower respiratory capacity per mitochondrion in
skeletal muscle of type 2 diabetic patients compared with obese subjects. Muscle
biopsies obtained from 10 obese type 2 diabetic and 8 obese nondiabetic ... Cited by 50 - Related articles - BL Direct - All 6 versions
- ►pubget.com [PDF] VB Schrauwen-Hinderling, ME Kooi, MKC … - Diabetologia, 2007 - Springer Page 1. ARTICLE Impaired in vivo mitochondrial function but similar
intramyocellular lipid content in patients with type 2 diabetes ... Cited by 41 - Related articles - BL Direct - All 5 versions
J Szendroedi, AI Schmid, M Chmelik, C Toth, … - PLoS Med, 2007 - medicine.plosjournals.org We measured G-6-P, ATP synthetic flux (ie, synthesis) and lipid contents of
skeletal muscle with 31 P/ 1 H magnetic resonance spectroscopy in ten patients
with T2DM and in two control groups: ten sex-, age-, and body mass-matched ... Cited by 40 - Related articles - Cached - All 9 versions
KF Petersen, S Dufour, GI Shulman - PLoS Medicine, 2005 - medicine.plosjournals.org Rates of insulin-stimulated muscle mitochondrial ATP synthase flux and
insulin-stimulated increases in concentrations of intramyocellular inorganic
phosphate (P i ) were assessed by 31 P magnetic resonance spectroscopy ... Cited by 101 - Related articles - Cached - BL Direct - All 12 versions
- ►nih.gov K Morino, KF Petersen, S Dufour, D Befroy, J … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig To further explore the nature of the mitochondrial dysfunction and insulin
resistance that occur in the muscle of young, lean, normoglycemic,
insulin-resistant offspring of parents with type 2 diabetes (IR offspring), ... Cited by 165 - Related articles - BL Direct - All 10 versions
- ►nih.gov R Boushel, E Gnaiger, P Schjerling, M … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Insulin resistance and type 2 diabetes are associated
with mitochondrial dysfunction. The aim of the present study was to test the
hypothesis that oxidative phosphorylation and electron transport capacity ... Cited by 79 - Related articles - BL Direct - All 9 versions
- ►nrc-cnrc.gc.ca [PDF] R Rabøl, R Boushel, F Dela - Applied Physiology, Nutrition, and Metabolism, 2006 - article.pubs.nrc-cnrc.gc.ca Abstract: The cause of insulin resistance and type 2 diabetes is unknown. The
major part of insulin-mediated glucose dis- posal takes place in the skeletal
muscle, and increased amounts of intramyocellular lipid has been associated ... Cited by 23 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org FGS Toledo, EV Menshikova, VB Ritov, K … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE— Reduced mitochondrial capacity in skeletal muscle occurs in type 2
diabetic patients and in those at increased risk for this disorder, but the
extent to which mitochondrial dysfunction in type 2 diabetic patients is ... Cited by 49 - Related articles - BL Direct - All 5 versions
- ►shouxi.net KF Petersen, S Dufour, D Befroy, R Garcia, … - The New England journal of medicine, 2004 - nejm.highwire.org Methods We performed hyperinsulinemic–euglycemic clamp studies in combination
with infusions of [6,6- 2 H 2 ]glucose in healthy, young, lean,
insulin-resistant offspring of patients with type 2 diabetes and insulin- ... Cited by 780 - Related articles - BL Direct - All 14 versions
