- ►diabetesjournals.org KKY Cheng, KSL Lam, Y Wang, Y Huang, D Carling, D … - Diabetes, 2007 - Am Diabetes Assoc Adiponectin protects the vascular system partly through stimulation of endothelial nitric oxide
(NO) production and endothelium-dependent vasodilation. The current study investigated the
role of two recently identified adiponectin receptors, AdipoR1 and -R2, and their ... Cited by 40 - Related articles - BL Direct - All 5 versions
KK Cheng, KS Lam, Y Wang, H Yu, D Carling, D Wu, C … - Diabetes, 2007 - Am Diabetes Assoc Page 1. Adiponectin-induced eNOS activation and Nitric Oxide Production are
Mediated by APPL1 in Endothelial Cells Received for publication 12 November
2006 and accepted in revised form 29 January 2007. Kenneth KY ... Cited by 7 - Related articles
- ►jbc.org B Chandrasekar, WH Boylston, K Venkatachalam, … - Journal of Biological …, 2008 - ASBMB The adipocyte-derived cytokine adiponectin is known to exert anti-inflammatory and anti-apoptotic
effects. In patients with atherosclerotic cardiovascular disease, circulating levels of adiponectin
correlate inversely with those of the proinflammatory, proapoptotic cytokine interleukin ... Cited by 8 - Related articles - All 5 versions
- ►jbc.org T Saito, CC Jones, S Huang, MP Czech, PF Pilch - Journal of Biological …, 2007 - ASBMB APPL1 (adaptor protein containing PH domain, PTB domain, and leucine zipper motif 1) is an
Akt/protein kinase B-binding protein involved in signal transduction and membrane trafficking
pathways for various receptors, including receptor tyrosine kinases. Here, we establish a ... Cited by 16 - Related articles - All 6 versions
- ►jbc.org YC Levine, GK Li, T Michel - Journal of Biological Chemistry, 2007 - ASBMB The endothelial isoform of nitric-oxide synthase (eNOS), a key determinant of vascular
homeostasis, is a calcium/calmodulin-dependent phosphoprotein regulated by diverse cell surface
receptors. Vascular endothelial growth factor (VEGF) and sphingosine 1-phosphate (S1P) ... Cited by 34 - Related articles - All 6 versions
- ►endojournals.org Y Liu, MD Michael, S Kash, WR Bensch, BP Monia, SF … - Endocrinology, 2007 - Endocrine Soc Adiponectin/adiponectin receptors (AdipoR) are involved in energy homeostasis and inflammatory
pathways. To investigate the role of AdipoR2 in metabolic control, we studied the lipid and glucose
metabolic phenotypes in AdipoR2-deficient mice. AdipoR2 deletion diminished high-fat ... Cited by 26 - Related articles - BL Direct - All 5 versions
W Xi, H Satoh, H Kase, K Suzuki, Y Hattori - Biochemical and Biophysical …, 2005 - Elsevier The present study examined potential interactions between endothelial NO synthase
(eNOS), heat shock protein (HSP)90, and Akt in vascular endothelial cells stimulated with globular
adiponectin to produce nitric oxide (NO). Globular adiponectin-induced eNOS ... Cited by 37 - Related articles - All 4 versions
- ►ahajournals.org W Sun, TS Lee, M Zhu, C Gu, Y Wang, Y Zhu, JYJ Shyy - Circulation, 2006 - Am Heart Assoc Methods and Results— Western blotting of protein extracts from human umbilical vein endothelial
cells treated with atorvastatin revealed increased phosphorylation of AMPK at Thr-172 in a
time- and dose-dependent manner. The AMPK activity, assessed by SAMS assay, was ... Cited by 44 - Related articles - All 6 versions
KSL Lam, A Xu - Current Diabetes Reports, 2005 - Springer Introduction Obesity, especially central obesity, has been shown to predict cardiovascular morbidity
and mortality in long-term epide- miologic studies [1,2]. Although this may be attributed to its
association with insulin resistance and other related cardio- vascular risk factors, such as ... Cited by 54 - Related articles - BL Direct - All 2 versions
