M Mogensen, K Sahlin, M Fernström, D … - Diabetes, 2007 - Am Diabetes Assoc We tested the hypothesis of a lower respiratory capacity per mitochondrion in
skeletal muscle of type 2 diabetic patients compared with obese subjects. Muscle
biopsies obtained from 10 obese type 2 diabetic and 8 obese nondiabetic ... Cited by 50 - Related articles - BL Direct - All 6 versions
- ►nih.gov R Boushel, E Gnaiger, P Schjerling, M … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Insulin resistance and type 2 diabetes are associated
with mitochondrial dysfunction. The aim of the present study was to test the
hypothesis that oxidative phosphorylation and electron transport capacity ... Cited by 79 - Related articles - BL Direct - All 9 versions
- ►pubget.com [PDF] VB Schrauwen-Hinderling, ME Kooi, MKC … - Diabetologia, 2007 - Springer Page 1. ARTICLE Impaired in vivo mitochondrial function but similar
intramyocellular lipid content in patients with type 2 diabetes ... Cited by 41 - Related articles - BL Direct - All 5 versions
M Mogensen, K Sahlin, M Fernström, D … - Am Diabetes Assoc Page 1. Mitochondrial respiration is decreased in skeletal muscle of patients with
type 2 diabetes Running title: Mitochondrial dysfunction in type 2 diabetes ... Related articles
J Szendroedi, AI Schmid, M Chmelik, C Toth, … - PLoS Med, 2007 - medicine.plosjournals.org We measured G-6-P, ATP synthetic flux (ie, synthesis) and lipid contents of
skeletal muscle with 31 P/ 1 H magnetic resonance spectroscopy in ten patients
with T2DM and in two control groups: ten sex-, age-, and body mass-matched ... Cited by 40 - Related articles - Cached - All 9 versions
DE Befroy, KF Petersen, S Dufour, GF Mason … - Diabetes, 2007 - Am Diabetes Assoc Insulin resistance is the best predictor for the development of diabetes in
offspring of type 2 diabetic patients, but the mechanism responsible for it
remains unknown. Recent studies have demonstrated increased ... Cited by 68 - Related articles - BL Direct - All 6 versions
- ►physiology.org GP Holloway, A Thrush, GJF Heigenhauser, … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc A reduction in fatty acid oxidation has been associated with lipid accumulation
and insulin resistance in the skeletal muscle of obese individuals. We examined
whether this decrease in fatty acid oxidation was attributable to a ... Cited by 23 - Related articles - BL Direct - All 7 versions
C Bonnard, A Durand, S Peyrol, E Chanseaume … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Mitochondrial dysfunction in skeletal muscle has been implicated in the
development of type 2 diabetes. However, whether these changes are a cause or a
consequence of insulin resistance is not clear. We investigated the ... Cited by 51 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org FGS Toledo, EV Menshikova, VB Ritov, K … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE— Reduced mitochondrial capacity in skeletal muscle occurs in type 2
diabetic patients and in those at increased risk for this disorder, but the
extent to which mitochondrial dysfunction in type 2 diabetic patients is ... Cited by 49 - Related articles - BL Direct - All 5 versions
- ►eje.org HM De Feyter, NMA van den Broek, SFE Praet, … - European Journal of Endocrinology, 2008 - eje.org Objective: Several lines of evidence support a potential role of skeletal muscle
mitochondrial dysfunction in the pathogenesis of insulin resistance and/or type
2 diabetes. However, it remains to be established whether mitochondrial ... Cited by 10 - Related articles - BL Direct - All 5 versions
