- ►diabetesjournals.org M Krebs, B Brunmair, A Brehm, M Artwohl, J … - Diabetes, 2007 - Am Diabetes Assoc Type 2 diabetes is closely linked to obesity and insulin resistance (1–3). In addition to polygenic
predisposition, environmental factors including quality and quantity of food supply, dietary
behavior, and physical activity are of major importance for the development of type 2 ... Cited by 26 - Related articles - BL Direct - All 5 versions
M Krebs, B Brunmair, A Brehm, M Artwohl, J … - Am Diabetes Assoc The mTOR-pathway regulates nutrient sensitive glucose uptake in man ... Received for publication
21 July 2006 and accepted in revised form 20 February 2007. ... Michael Krebs1, Barbara
Brunmair1, Attila Brehm1, Michaela Artwohl1, Julia Szendroedi1, Peter Nowotny1, Erich ... Related articles
JE Kim, J Chen - Diabetes, 2004 - Am Diabetes Assoc Adipocyte differentiation is a developmental process that is critical for metabolic homeostasis
and nutrient signaling. The mammalian target of rapamycin (mTOR) mediates nutrient signaling
to regulate cell growth, proliferation, and diverse cellular differentiation. It has been ... Cited by 42 - Related articles - BL Direct - All 4 versions
F Tremblay, M Krebs, L Dombrowski, A Brehm, E … - Diabetes, 2005 - Am Diabetes Assoc To examine the molecular mechanisms by which plasma amino acid elevation impairs insulin
action, we studied seven healthy men twice in random order during infusion of an amino acid
mixture or saline (total plasma amino acid ∼6 vs. ∼2 mmol/l). ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org Z Szocs, B Brunmair, K Stadlbauer, P Nowotny, L … - Journal of Pharmacology …, 2008 - ASPET Zucker diabetic fatty (ZDF) rats are a standard animal model for the study of type 2 diabetes and
for pharmacological characterization of insulin-sensitizing drugs. To analyze the age-dependent
development of their metabolic derangements and the associated changes in their ... Cited by 3 - Related articles - All 3 versions
[CITATION] Posttransplantation Diabetes Mellitus in kidney transplant recipients receiving …
- ►cell.com SH Um, D D'Alessio, G Thomas - Cell metabolism, 2006 - Elsevier Nutrient overload leads to obesity, insulin resistance, and often type 2 diabetes. Whereas increased
fat intake is commonly cited as the major factor in diet-induced dysmetabolic states, increased
protein consumption also contributes, through elevated circulating amino acids. Recent ... Cited by 89 - Related articles - All 9 versions
G Leibowitz, E Cerasi, M Ketzinel- … - Diabetes, Obesity and …, 2008 - interscience.wiley.com Mammalian target of rapamycin (mTOR) is an important nutrient sensor that plays a critical role
in cellular metabolism, growth, proliferation and apoptosis and in the cellular response to oxidative
stress. In addition, mTOR–raptor complex, also called mammalian target of rapamycin ... Cited by 4 - Related articles - All 3 versions
- ►physiology.org AM Miller, JR Brestoff, CB Phelps, EZ Berk … - American Journal of …, 2008 - Am Physiological Soc Studies of cultured cells have indicated that the mammalian target of rapamycin complex 1
(mTORC1) mediates the development of insulin resistance. Because a role for mTORC1 in the
development of skeletal muscle insulin resistance has not been established, we studied ... Cited by 4 - Related articles - All 3 versions
