- ►diabetesjournals.org RH Wallis, KS Wang, D Dabrowski, L Marandi, T Ning, … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—The biobreeding diabetes-prone (BBDP) rat spontaneously develops type 1
diabetes. Two of the genetic factors contributing to this syndrome are the major histocompatibility
complex (Iddm1) and a Gimap5 mutation (Iddm2) responsible for a T-lymphopenia. ... Cited by 2 - Related articles - BL Direct - All 7 versions
JP Mordes, L Cort, E Norowski, J Leif, JM Fuller, Å … - Mammalian Genome, 2009 - Springer Abstract Iddm14 (formerly Iddm4) is a non-MHC-linked genetic locus associated with autoimmune
diabetes. Its effects have been well-documented in BB-derived rats in which diabetes is either
induced by immunologic perturba- tion or occurs spontaneously. The role of Iddm14 in ... Cited by 4 - Related articles - All 2 versions
EP Blankenhorn, C DeScipio, L Rodemich, L … - Ann NY Acad …, 2007 - interscience.wiley.com Abstract : Iddm4 is a dominant non-major histocompatibility complex (MHC) determinant of diabetes
susceptibility in BBDR rats treated with poly I:C, plus depletion of regulatory T cells. In congenic
MHC-identical normal WF rats, Iddm4 d sensitively and specifically predicts induced ... Cited by 4 - Related articles - BL Direct - All 6 versions
M Stienekemeier, K Hofmann, R Gold, T Herrmann - Immunogenetics, 2000 - Springer Page 1. Immunogenetics (2000) 51:296–305 Q Springer-Verlag 2000 ORIGINAL
PAPER Martina Stienekemeier 7 Kathrin Hofmann Ralf Gold 7 Thomas Herrmann
A polymorphism of the rat T-cell receptor b -chain variable gene 13 ... Cited by 4 - Related articles - All 2 versions
JM Fuller, AE Kwitek, TJ Hawkins, DH Moralejo, W Lu, … - Diabetes, 2006 - Am Diabetes Assoc Failure to express the Gimap5 protein is associated with lymphopenia (lyp) and linked to spontaneous
diabetes in the diabetes-prone BioBreeding (BBDP) rat. Gimap5 is a member of seven related
genes located within 150 Kb on rat chromosome 4. Congenic DR. lyp/lyp rats, where ... Cited by 6 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org EP Blankenhorn, L Rodemich, C Martin-Fernandez, J … - Diabetes, 2005 - Am Diabetes Assoc BBDR rats develop autoimmune diabetes only after challenge with environmental
perturbants. These perturbants include polyinosinic:polycytidylic acid (poly I:C, a ligand of
toll-like receptor 3), agents that deplete regulatory T-cell (Treg) populations, and a non–β- ... Cited by 12 - Related articles - All 6 versions
I Klöting, J Van Den Brandt, P Kovacs - International journal of …, 1998 - ncbi.nlm.nih.gov Several crossing studies using diabetic BB/OK and diabetes-resistant rat strains have clearly
shown that the MHC class-II-genes of the RT1u haplotype (Iddm1) and the lymphopenia
(Iddm2) are essential but not sufficient for type 1 diabetes development. The search for ... Cited by 8 - Related articles - BL Direct - All 2 versions
DMR Rev - Diabetes Metab Res Rev, 2007 - biochemie.uni-greifswald.de Diabetes Metab Res Rev 2007; 23: 406–410. Published online 18 December 2006 in Wiley InterScience
(www.interscience.wiley.com) DOI: 10.1002/dmrr.713 ... Triplet repeat in the Repin1 3 -untranslated
region ... Department of Laboratory Animal Science, Medical Faculty, University of ... Cited by 3 - Related articles - View as HTML - BL Direct - All 4 versions
L HORNUM, D LUNDSGAARD, H … - ANNALS-NEW YORK …, 2007 - interscience.wiley.com Abstract : The Iddm4 gene controls diabetes in rats depleted of regulatory T cells (T reg ) and
immune-activated via treatment with the toll-like receptor 3 (TLR-3) ligand, polyI:C. Both
diabetes-resistant (BBDR) and diabetes-prone (BBDP) BB rats carry dominant permissive ... Cited by 3 - Related articles - BL Direct - All 4 versions
DP Gold, ST Shaikewitz, D Mueller, JR Redd, KS … - …, 1995 - informahealthcare.com Autoimmunity, 1995, Vol. 22, pp. 149-161 Reprints available directly from the publisher Photocopying
permitted by license only ... 0 1995 OPA (Overseas Publishers Association) Amsterdam BV Published
in The Netherlands by Harwood Academic Publishers GmbH Printed in Singapore Cited by 3 - Related articles - BL Direct - All 5 versions
