PD Cani, J Amar, MA Iglesias, M Poggi, C … - Diabetes, 2007 - Am Diabetes Assoc Diabetes and obesity are two metabolic diseases characterized by insulin
resistance and a low-grade inflammation. Seeking an inflammatory factor
causative of the onset of insulin resistance, obesity, and diabetes, we ... Cited by 149 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org PD Cani, R Bibiloni, C Knauf, A Waget, AM … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—We found that changes of gut microbiota induced by an antibiotic
treatment reduced metabolic endotoxemia and the cecal content of LPS in both
high-fat–fed and ob/ob mice. This effect was correlated with reduced ... Cited by 60 - Related articles - All 5 versions
F Bäckhed, JK Manchester, CF Semenkovich, … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences The trillions of microbes that colonize our adult intestines function
collectively as a metabolic organ that communicates with, and complements, our
own human metabolic apparatus. Given the worldwide epidemic in obesity, ... Cited by 117 - Related articles - BL Direct - All 10 versions
- ►ucl.ac.be [PDF] PD Cani, AM Neyrinck, F Fava, C Knauf, RG … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Recent evidence suggests that a particular gut
microbial community may favour occurrence of the metabolic diseases. Recently,
we reported that high-fat (HF) feeding was associated with higher ... Cited by 62 - Related articles - BL Direct - All 3 versions
- ►fasebj.org M Membrez, F Blancher, M Jaquet, R Bibiloni, … - The FASEB Journal, 2008 - FASEB Recent data suggest that the gut microbiota plays a significant role in fat
accumulation. However, it is not clear whether gut microbiota is involved in the
pathophysiology of type 2 diabetes. To assess this issue, we modulated gut ... Cited by 29 - Related articles - All 6 versions
- ►physiology.org SJ Creely, PG McTernan, CM Kusminski… - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Type 2 diabetes (T2DM) is associated with chronic low-grade inflammation.
Adipose tissue (AT) may represent an important site of inflammation. 3T3-L1
studies have demonstrated that lipopolysaccharide (LPS) activates toll-like ... Cited by 62 - Related articles - BL Direct - All 6 versions
PD Cani, J Amar, R Burcelin - Obésité, 2007 - Springer Résumé : Le développement quasi paralle`le des maladies métaboliques et du
changement des habitudes alimen- taires montre qu'en plus d'une composante
génomique propre a` chaque organisme, un événement nutritionnel doit ... Related articles - BL Direct
- ►physiology.org P Brun, I Castagliuolo, VD Leo, A Buda, M … - American Journal of Physiology- Gastrointestinal and …, 2007 - Am Physiological Soc A small percentage of pathologically obese subjects with fatty livers develop
histological signs of necroinflammation and fibrosis, suggesting a variety of
cofactors in the pathogenesis of obesity-related liver diseases including ... Cited by 62 - Related articles - BL Direct - All 6 versions
- ►sciencemag.org F Bäckhed, H Ding, T Wang, LV Hooper, GY … - Proceedings of the National Academy of Sciences, 2004 - National Acad Sciences New therapeutic targets for noncognitive reductions in energy intake,
absorption, or storage are crucial given the worldwide epidemic of obesity. The
gut microbial community (microbiota) is essential for processing dietary ... Cited by 372 - Related articles - BL Direct - All 12 versions