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Scholar Results 1 - 10 of about 101 related to Cani: Metabolic endotoxemia initiates obesity and insulin resistance. (0.11 sec) 

Metabolic endotoxemia initiates obesity and insulin resistance


PD Cani, J Amar, MA Iglesias, M Poggi, C … - Diabetes, 2007 - Am Diabetes Assoc
Diabetes and obesity are two metabolic diseases characterized by insulin
resistance and a low-grade inflammation. Seeking an inflammatory factor
causative of the onset of insulin resistance, obesity, and diabetes, we ...
Cited by 149 - Related articles - BL Direct - All 10 versions

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat …

- diabetesjournals.org
PD Cani, R Bibiloni, C Knauf, A Waget, AM … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We found that changes of gut microbiota induced by an antibiotic
treatment reduced metabolic endotoxemia and the cecal content of LPS in both
high-fat–fed and ob/ob mice. This effect was correlated with reduced ...
Cited by 60 - Related articles - All 5 versions

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice


F Bäckhed, JK Manchester, CF Semenkovich, … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
The trillions of microbes that colonize our adult intestines function
collectively as a metabolic organ that communicates with, and complements, our
own human metabolic apparatus. Given the worldwide epidemic in obesity, ...
Cited by 117 - Related articles - BL Direct - All 10 versions

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced …

- ucl.ac.be [PDF] 
PD Cani, AM Neyrinck, F Fava, C Knauf, RG … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Recent evidence suggests that a particular gut
microbial community may favour occurrence of the metabolic diseases. Recently,
we reported that high-fat (HF) feeding was associated with higher ...
Cited by 62 - Related articles - BL Direct - All 3 versions

Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in …

- fasebj.org
M Membrez, F Blancher, M Jaquet, R Bibiloni, … - The FASEB Journal, 2008 - FASEB
Recent data suggest that the gut microbiota plays a significant role in fat
accumulation. However, it is not clear whether gut microbiota is involved in the
pathophysiology of type 2 diabetes. To assess this issue, we modulated gut ...
Cited by 29 - Related articles - All 6 versions

Lipopolysaccharide activates an innate immune system response in human adipose tissue in …

- physiology.org
SJ Creely, PG McTernan, CM Kusminski… - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Type 2 diabetes (T2DM) is associated with chronic low-grade inflammation.
Adipose tissue (AT) may represent an important site of inflammation. 3T3-L1
studies have demonstrated that lipopolysaccharide (LPS) activates toll-like ...
Cited by 62 - Related articles - BL Direct - All 6 versions

Une flore intestinale saine pour un métabolisme énergétique sain


PD Cani, J Amar, R Burcelin - Obésité, 2007 - Springer
Résumé : Le développement quasi paralle`le des maladies métaboliques et du
changement des habitudes alimen- taires montre qu'en plus d'une composante
génomique propre a` chaque organisme, un événement nutritionnel doit ...
Related articles - BL Direct

Increased intestinal permeability in obese mice: new evidence in the pathogenesis of …

- physiology.org
P Brun, I Castagliuolo, VD Leo, A Buda, M … - American Journal of Physiology- Gastrointestinal and …, 2007 - Am Physiological Soc
A small percentage of pathologically obese subjects with fatty livers develop
histological signs of necroinflammation and fibrosis, suggesting a variety of
cofactors in the pathogenesis of obesity-related liver diseases including ...
Cited by 62 - Related articles - BL Direct - All 6 versions

The gut microbiota as an environmental factor that regulates fat storage

- sciencemag.org
F Bäckhed, H Ding, T Wang, LV Hooper, GY … - Proceedings of the National Academy of Sciences, 2004 - National Acad Sciences
New therapeutic targets for noncognitive reductions in energy intake,
absorption, or storage are crucial given the worldwide epidemic of obesity. The
gut microbial community (microbiota) is essential for processing dietary ...
Cited by 372 - Related articles - BL Direct - All 12 versions

Microbial ecology: human gut microbes associated with obesity


RE Ley, PJ Turnbaugh, S Klein, JI Gordon - Nature, 2006 - adsabs.harvard.edu
Cited by 335 - Related articles - BL Direct - All 7 versions


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