- ►diabetesjournals.org C Arden, A Trainer, N de la Iglesia, KT … - Diabetes, 2007 - Am Diabetes Assoc Mutations in the glucokinase (GK) gene cause defects in blood glucose
homeostasis. In some cases (V62M and G72R), the phenotype cannot be explained by
altered enzyme kinetics or protein instability. We used transient and ... Cited by 7 - Related articles - BL Direct - All 4 versions
C Arden, L Hampson, G Huang, J Shaw, A … - Biochem. J, 2008 - biochemj.org PFK-2/FBPase-2 (6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase) catalyses
the formation and degradation of fructose 2,6-P 2 (fructose 2,6-bisphosphate)
and is also a glucokinase-binding protein. The role of fructose 2,6-P 2 in ... Cited by 1 - Related articles - Cached - BL Direct - All 5 versions
A Gloyn, N Tribble, M Bunt, A Barrett, P … - Biochemical Society Transactions, 2008 - biochemsoctrans.org There are well-documented examples in the literature of where determining the
genetic aetiology of a disorder has provided insights into important regulatory
pathways and protein interactions, and, more recently, has led to improved ... Cited by 3 - Related articles - Cached - BL Direct - All 5 versions
L Bjorkhaug, J Molnes, O Sovik, PR Njolstad, … - Journal of biological chemistry, 2007 - ASBMB Running Title: Glucokinase activation and proteasomal degradation ... 1 Address
correspondence to: Torgeir Flatmark, Department of Biomedicine, University of
Bergen, Jonas Lies vei 91, 5009 Bergen, Norway. Tel.: +47 55586428; Fax:+ ... Cited by 8 - Related articles - All 6 versions
- ►endojournals.org S Baltrusch, S Langer, L Massa, M Tiedge, S … - Endocrinology, 2006 - Endocrine Soc The glucose sensor enzyme glucokinase plays a pivotal role in the regulation of
glucose-induced insulin secretion in pancreatic ß-cells. Activation of
glucokinase represents a promising concept for the treatment of type 2 ... Cited by 8 - Related articles - BL Direct - All 4 versions
C Arden, A Trainer, N de la Iglesia, KT … - DIABETES, 2007 - Am Diabetes Assoc Page 1. Original Article Cell Biology Assessment of Glucokinase Mutations
V62M and G72R in Pancreatic -Cells Evidence for Cellular ... Related articles
C Arden, A Trainer, N de la Iglesia, KT … - Am Diabetes Assoc Page 1. Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic
beta-cells: evidence for cellular instability of catalytic activity. ... Related articles
C Arden, A Trainer, N de la Iglesia, KT … - 糖尿病学杂志, 2007 - journal.shouxi.net 【摘要】 Mutations in the glucokinase (GK) gene cause defects in blood
glucose homeostasis. In some cases (V62M and G72R), the phenotype cannot be
explained by altered enzyme kinetics or protein instability. We used ... Related articles - Cached
J Sommercorn, T Steward, RA Freedland - Archives of biochemistry and biophysics, 1984 - ncbi.nlm.nih.gov 6-Phosphogluconate activates phosphofructokinase from liver, adipose tissue,
kidney, and skeletal muscle by decreasing the apparent S0.5 for fructose
6-phosphate without affecting the maximum velocity. The response of ... Cited by 5 - Related articles
F Watanabe, E Furuya - Biochemical and Biophysical Research …, 2001 - Elsevier Three C-terminal sequences (VSIPVV, VCKWT, and LTLLS) of rat heart-type
fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase have been reported. To
elucidate the mechanism of generating the heterogeneity of the enzyme, we ... Cited by 5 - Related articles - BL Direct - All 6 versions
