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Scholar Results 1 - 10 of about 101 related to Hajri: CD36-facilitated fatty acid uptake inhibits leptin production and signaling in adipose tissue. (0.12 sec) 

CD36-facilitated fatty acid uptake inhibits leptin production and signaling in …


T Hajri, AM Hall, DR Jensen, TA Pietka, VA Drover, H … - Diabetes, 2007 - Am Diabetes Assoc
Leptin plays an important role in regulating energy expenditure in response to food intake, but
nutrient regulation of leptin is incompletely understood. In this study using in vivo and in vitro
approaches, we examined the role of fatty acid uptake in modulating leptin expression ...
Cited by 16 - Related articles - BL Direct - All 5 versions

Opposite regulation of CD36 ubiquitination by fatty acids and insulin: effects on …

- jbc.org
J Smith, X Su, R El-Maghrabi, PD Stahl, NA … - Journal of Biological …, 2008 - ASBMB
FAT/CD36 is a membrane scavenger receptor that facilitates long chain fatty acid uptake by
muscle. Acute increases in membrane CD36 and fatty acid uptake have been reported in response
to insulin and contraction. In this study we have explored protein ubiquitination as one ...
Cited by 3 - Related articles - All 5 versions

CD36 mediates both cellular uptake of very long chain fatty acids and their …


VA Drover, DV Nguyen, CC Bastie, YF Darlington, … - Journal of Biological …, 2008 - ASBMB
The intestine has an extraordinary capacity for fatty acid (FA) absorption. Numerous candidates
for a protein-mediated mechanism of dietary FA absorption have been proposed, but firm evidence
for this process has remained elusive. Here we show that the scavenger receptor CD36 is ...
Cited by 11 - Related articles - All 7 versions

Fatty acid transport protein 4 is dispensable for intestinal lipid absorption in mice


J Shim, CL Moulson, EP Newberry, MH Lin, Y Xie, … - The Journal of Lipid …, 2009 - ASBMB
FA transport protein 4 (FATP4), one member of a multigene family of FA transporters, was proposed
as a major FA transporter in intestinal lipid absorption. Due to the fact that Fatp4 –/– mice die
because of a perinatal skin defect, we rescued the skin phenotype using an FATP4 ...
Cited by 9 - Related articles - All 6 versions

Physiological and pathological roles of a multi-ligand receptor CD36 in …


S Yamashita, KI Hirano, T Kuwasako, M Janabi, Y … - Molecular and cellular …, 2007 - Springer
Oxidized low density lipoprotein (LDL) (Ox-LDL) plays an important role in the pathogenesis
of atherosclerosis. Oxidized LDL is taken up by macrophages via scavenger receptors. CD36
is an 88 kDa glycoprotein expressed on platelets, monocyte- macrophages, ...
Cited by 31 - Related articles - BL Direct - All 5 versions

CD36 is important for chylomicron formation and secretion and may mediate …

- nih.gov
AM Nauli, F Nassir, S Zheng, Q Yang, CM Lo, SB … - Gastroenterology, 2006 - Elsevier
The transmembrane protein CD36 is expressed in many cell types, including platelets, 1
monocytes, 2 capillary endothelial cells, 3 erythroblasts, 4 adipocytes, 5 and intestinal, 6 , 7 and
8 mammary, and retinal epithelial cells. 9 In rat intestinal epithelial cells, CD36 is ...
Cited by 25 - Related articles - All 19 versions

Regulation of fatty acid uptake into tissues: lipoprotein lipase-and CD36-mediated …

- bdwm.net [PDF] 
IJ Goldberg, RH Eckel, NA Abumrad - The Journal of Lipid Research, 2009 - ASBMB
Cells obtain FAs either from LPL-catalyzed hydrolysis of lipoprotein triglyceride or from unesterified
FFAs associated with albumin. LPL also influences uptake of esterified lipids such as cholesteryl
and retinyl esters that are not hydrolyzed in the plasma. This process might not involve ...
Cited by 6 - Related articles - All 5 versions

Regulation of receptors and transporters by ubiquitination: new insights into …

- aspetjournals.org
M Miranda, A Sorkin - Molecular Interventions, 2007 - ASPET
The function of many receptors and transport proteins that reside at the surface of the cell is regulated
by endocytosis and postendocytic trafficking. Modification of receptors and transporters by ubiquitin
conjugation has recently emerged as the major regulatory mechanism of internalization ...
Cited by 26 - Related articles - All 2 versions

CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons …

- nih.gov
VA Drover, M Ajmal, F Nassir, NO … - Journal of Clinical …, 2005 - Am Soc Clin Investig
CD36 mediates the transfer of fatty acids (FAs) across the plasma membranes of muscle and
adipose cells, thus playing an important role in regulating peripheral FA metabolism in vivo. In
the proximal intestine, CD36 is localized in abundant quantities on the apical surface of ...
Cited by 45 - Related articles - All 10 versions

CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPARδ/β-mediated …


Z Nahlé, M Hsieh, T Pietka, CT Coburn, PA … - Journal of Biological …, 2008 - ASBMB
The transcription factor FoxO1 contributes to the metabolic adaptation to fasting by suppressing
muscle oxidation of glucose, sparing it for glucose-dependent tissues. Previously, we reported
that FoxO1 activation in C 2 C 12 muscle cells recruits the fatty acid translocase CD36 to ...
Cited by 7 - Related articles - All 9 versions


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