RJF Loos, PW Franks, RW Francis, I Barroso, … - Diabetes, 2007 - Am Diabetes Assoc Rapidly accumulating evidence shows that common T-cell transcription factor
(TCF)7L2 polymorphisms confer risk of type 2 diabetes through unknown
mechanisms. We examined the association between four TCF7L2 single ... Cited by 53 - Related articles - BL Direct - All 8 versions
- ►pubget.com [PDF] J Wang, J Kuusisto, M Vänttinen, T Kuulasmaa … - Diabetologia, 2007 - Springer Page 1. ARTICLE Variants of transcription factor 7-like 2 (TCF7L2) gene predict
conversion to type 2 diabetes in the Finnish Diabetes ... Cited by 51 - Related articles - BL Direct - All 4 versions
- ►nih.gov V Lyssenko, L Groop - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Genetic variants in the gene encoding for transcription factor-7–like 2
(TCF7L2) have been associated with type 2 diabetes (T2D) and impaired β cell
function, but the mechanisms have remained unknown. We therefore studied ... Cited by 136 - Related articles - BL Direct - All 13 versions
RJF Loos, PW Franks, RW Francis, I Barroso, … - Am Diabetes Assoc TCF7L2 polymorphisms modulate proinsulin levels and β-cell function in a
British Europid population ... Received for publication 12 January 2007 and
accepted in revised form 28 March 2007. ... Additional information for ... Related articles
J Munoz, KH Lok, BA Gower, JR Fernandez, … - Diabetes, 2006 - Am Diabetes Assoc Recently, the transcription factor 7-like 2 (TCF7L2) gene on chromosome 10q25.2
has been linked with type 2 diabetes among Caucasians, with disease associations
noted for single nucleotide polymorphisms (SNPs) rs12255372 and rs7903146. ... Cited by 53 - Related articles - BL Direct - All 5 versions
- ►nih.gov SA Schäfer, O Tschritter, F Machicao, C Thamer … - Diabetologia, 2007 - Springer Page 1. ARTICLE Impaired glucagon-like peptide-1-induced insulin secretion in carriers
of transcription factor 7-like 2 (TCF7L2) gene polymorphisms ... Cited by 57 - Related articles - BL Direct - All 9 versions
- ►utah.edu [PDF] JC Florez - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com Purpose of review Common variants in the gene that encodes the transcription
factor 7-like 2 (TCF7L2) have been strongly associated with type 2 diabetes.
This highly reproducible association may uncover novel mechanisms of ... Cited by 36 - Related articles - BL Direct - All 4 versions
K Kirchhoff, F Machicao, A Haupt, SA Schäfer, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Variation within six novel genetic loci has been
reported to confer risk of type 2 diabetes and may be associated with beta cell
dysfunction. We investigated whether these polymorphisms are also ... Cited by 38 - Related articles - BL Direct - All 3 versions
S Cauchi, D Meyre, H Choquet, C Dina, C Born … - Diabetes, 2006 - Am Diabetes Assoc Recently, case-control studies demonstrated that a TCF7L2 (transcription factor
7–like 2 gene) noncoding variant (rs7903146 T at-risk allele) was strongly
associated with an increased risk of type 2 diabetes. However, the ... Cited by 54 - Related articles - BL Direct - All 4 versions
R Saxena, L Gianniny, NP Burtt, V Lyssenko, … - Diabetes, 2006 - Am Diabetes Assoc Recently, common noncoding variants in the TCF7L2 gene were strongly associated
with increased risk of type 2 diabetes in samples from Iceland, Denmark, and the
US We genotyped 13 single nucleotide polymorphisms (SNPs) across TCF7L2 in ... Cited by 160 - Related articles - BL Direct - All 4 versions
